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Gastrograffin use in distal intestinal obstruction syndrome of cystic fibrosis.
J Ayub Med Coll Abbottabad 2007 Jan-Mar; 19(1):58-60JA

Abstract

BACKGROUND

Meconium ileus equivalent or the Distal Intestinal Obstruction Syndrome (DIOS) is an entity that is frequently seen in patients with cystic fibrosis (CF). In the gastrointestinal tract cystic fibrosis may produces symptoms of malabsorption and constipation. The latter may be associated with complications such as impaction and intestinal perforation. Meconium ileus and DIOS are an emergency and requires to be treated aggressively to ensure that consequences such as perforation do not occur.

METHOD

Traditional modes of management of DIOS have included the use of laxatives, Acetylcysteine and Gastrograffin enemas. We are describing the use of oral gastrograffin in our patient seen at the Aga Khan University Hospital where small bowel obstruction was refractory to treatment. Oral gastrograffin was used once diluted in 4 times the volume of water or fruit juice with half doses given on day 2 and 3.

RESULTS

Oral gastrograffin use was followed by relief of obstruction in this patient.

CONCLUSION

Gastrograffin use orally or rectally may be helpful in the treatment of refractions distal intestinal obstruction syndrome in cystic fibrosis.

Authors+Show Affiliations

Department of Pediatrics, The Aga Khan University Hospital, Karachi, Pakistan. uzma.shah@aku.eduNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

17867484

Citation

Shah, Uzma, et al. "Gastrograffin Use in Distal Intestinal Obstruction Syndrome of Cystic Fibrosis." Journal of Ayub Medical College, Abbottabad : JAMC, vol. 19, no. 1, 2007, pp. 58-60.
Shah U, Shafiq Y, Khan MA. Gastrograffin use in distal intestinal obstruction syndrome of cystic fibrosis. J Ayub Med Coll Abbottabad. 2007;19(1):58-60.
Shah, U., Shafiq, Y., & Khan, M. A. (2007). Gastrograffin use in distal intestinal obstruction syndrome of cystic fibrosis. Journal of Ayub Medical College, Abbottabad : JAMC, 19(1), pp. 58-60.
Shah U, Shafiq Y, Khan MA. Gastrograffin Use in Distal Intestinal Obstruction Syndrome of Cystic Fibrosis. J Ayub Med Coll Abbottabad. 2007;19(1):58-60. PubMed PMID: 17867484.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gastrograffin use in distal intestinal obstruction syndrome of cystic fibrosis. AU - Shah,Uzma, AU - Shafiq,Yasir, AU - Khan,Muhammad Arif Mateen, PY - 2007/9/18/pubmed PY - 2007/11/14/medline PY - 2007/9/18/entrez SP - 58 EP - 60 JF - Journal of Ayub Medical College, Abbottabad : JAMC JO - J Ayub Med Coll Abbottabad VL - 19 IS - 1 N2 - BACKGROUND: Meconium ileus equivalent or the Distal Intestinal Obstruction Syndrome (DIOS) is an entity that is frequently seen in patients with cystic fibrosis (CF). In the gastrointestinal tract cystic fibrosis may produces symptoms of malabsorption and constipation. The latter may be associated with complications such as impaction and intestinal perforation. Meconium ileus and DIOS are an emergency and requires to be treated aggressively to ensure that consequences such as perforation do not occur. METHOD: Traditional modes of management of DIOS have included the use of laxatives, Acetylcysteine and Gastrograffin enemas. We are describing the use of oral gastrograffin in our patient seen at the Aga Khan University Hospital where small bowel obstruction was refractory to treatment. Oral gastrograffin was used once diluted in 4 times the volume of water or fruit juice with half doses given on day 2 and 3. RESULTS: Oral gastrograffin use was followed by relief of obstruction in this patient. CONCLUSION: Gastrograffin use orally or rectally may be helpful in the treatment of refractions distal intestinal obstruction syndrome in cystic fibrosis. SN - 1025-9589 UR - https://www.unboundmedicine.com/medline/citation/17867484/Gastrograffin_use_in_distal_intestinal_obstruction_syndrome_of_cystic_fibrosis_ L2 - http://babysfirsttest.org/newborn-screening/conditions/cystic-fibrosis-cf DB - PRIME DP - Unbound Medicine ER -