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Global standardization of glycated hemoglobin measurement: the position of the IFCC Working Group.
Clin Chem Lab Med. 2007; 45(8):1077-80.CC

Abstract

The measurement of glycated hemoglobin is central in the monitoring of glycemic control in patients with diabetes. There are at least 30 different laboratory assays commercially available to measure the proportion of HbA1c in blood. In 1995 the IFCC established a Working Group (IFCC WG-HbA1c) to achieve international standardization of HbA1c measurement. The main achievements can be summarized as follows: a) a reference measurement procedure has been established with purified primary calibrators; b) a network of reference laboratories has been developed worldwide; and c) work has begun on implementation of traceability to the IFCC reference system. The IFCC WG-HbA1c recognizes the recommendation of the IFCC-IUPAC Committee on Nomenclature, Properties and Units that the analyte measured by the IFCC reference measurement procedure has been defined as betaN1-deoxyfructosyl-hemoglobin and that the recommended measurement units are mmol/mol. The IFCC WG-HbA1c recommends maintaining the use of the name HbA1c in clinical practice.

Authors+Show Affiliations

Centre for Metrological Traceability in Laboratory Medicine (CIRME), Dept. Science and Biomedical Technology, University of Milano, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17867998

Citation

International Federation of Clinical Chemistry and Laboratory Medicine, IFCC Scientific Division, et al. "Global Standardization of Glycated Hemoglobin Measurement: the Position of the IFCC Working Group." Clinical Chemistry and Laboratory Medicine, vol. 45, no. 8, 2007, pp. 1077-80.
International Federation of Clinical Chemistry and Laboratory Medicine, IFCC Scientific Division, Mosca A, Goodall I, et al. Global standardization of glycated hemoglobin measurement: the position of the IFCC Working Group. Clin Chem Lab Med. 2007;45(8):1077-80.
Mosca, A., Goodall, I., Hoshino, T., Jeppsson, J. O., John, W. G., Little, R. R., Miedema, K., Myers, G. L., Reinauer, H., Sacks, D. B., & Weykamp, C. W. (2007). Global standardization of glycated hemoglobin measurement: the position of the IFCC Working Group. Clinical Chemistry and Laboratory Medicine, 45(8), 1077-80.
International Federation of Clinical Chemistry and Laboratory Medicine, IFCC Scientific Division, et al. Global Standardization of Glycated Hemoglobin Measurement: the Position of the IFCC Working Group. Clin Chem Lab Med. 2007;45(8):1077-80. PubMed PMID: 17867998.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Global standardization of glycated hemoglobin measurement: the position of the IFCC Working Group. AU - ,, AU - Mosca,Andrea, AU - Goodall,Ian, AU - Hoshino,Tadao, AU - Jeppsson,Jan O, AU - John,W Garry, AU - Little,Randie R, AU - Miedema,Kor, AU - Myers,Gary L, AU - Reinauer,Hans, AU - Sacks,David B, AU - Weykamp,Cas W, PY - 2007/9/18/pubmed PY - 2008/1/3/medline PY - 2007/9/18/entrez SP - 1077 EP - 80 JF - Clinical chemistry and laboratory medicine JO - Clin Chem Lab Med VL - 45 IS - 8 N2 - The measurement of glycated hemoglobin is central in the monitoring of glycemic control in patients with diabetes. There are at least 30 different laboratory assays commercially available to measure the proportion of HbA1c in blood. In 1995 the IFCC established a Working Group (IFCC WG-HbA1c) to achieve international standardization of HbA1c measurement. The main achievements can be summarized as follows: a) a reference measurement procedure has been established with purified primary calibrators; b) a network of reference laboratories has been developed worldwide; and c) work has begun on implementation of traceability to the IFCC reference system. The IFCC WG-HbA1c recognizes the recommendation of the IFCC-IUPAC Committee on Nomenclature, Properties and Units that the analyte measured by the IFCC reference measurement procedure has been defined as betaN1-deoxyfructosyl-hemoglobin and that the recommended measurement units are mmol/mol. The IFCC WG-HbA1c recommends maintaining the use of the name HbA1c in clinical practice. SN - 1434-6621 UR - https://www.unboundmedicine.com/medline/citation/17867998/Global_standardization_of_glycated_hemoglobin_measurement:_the_position_of_the_IFCC_Working_Group_ L2 - https://www.degruyter.com/document/doi/10.1515/CCLM.2007.246 DB - PRIME DP - Unbound Medicine ER -