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MMN or no MMN: no magnitude of deviance effect on the MMN amplitude.
Psychophysiology. 2008 Jan; 45(1):60-9.P

Abstract

Based on results showing that the "deviant-minus-standard" estimate of the mismatch negativity (MMN) amplitude increases with increasing amounts of deviance, it has been suggested that the MMN amplitude reflects the amount of difference between the neural representations of the standard and the deviant sound. However, the deviant-minus-standard waveform also includes an N1 difference. We tested the effects of the magnitude of deviance on MMN while minimizing this N1 confound. We found no significant magnitude of deviance effect on the genuine MMN amplitude. Thus we suggest that the average MMN amplitude does not reflect the difference between neural stimulus representations; rather it may index the percentage of detected deviants, each of which elicits an MMN response of uniform amplitude. These results are compatible with an explanation suggesting that MMN is involved in maintaining a neural representation of the auditory environment.

Authors+Show Affiliations

Institute of Psychology I, University of Leipzig, Leipzig, Germany. horvath@cogpsyphy.huNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17868262

Citation

Horváth, János, et al. "MMN or No MMN: No Magnitude of Deviance Effect On the MMN Amplitude." Psychophysiology, vol. 45, no. 1, 2008, pp. 60-9.
Horváth J, Czigler I, Jacobsen T, et al. MMN or no MMN: no magnitude of deviance effect on the MMN amplitude. Psychophysiology. 2008;45(1):60-9.
Horváth, J., Czigler, I., Jacobsen, T., Maess, B., Schröger, E., & Winkler, I. (2008). MMN or no MMN: no magnitude of deviance effect on the MMN amplitude. Psychophysiology, 45(1), 60-9.
Horváth J, et al. MMN or No MMN: No Magnitude of Deviance Effect On the MMN Amplitude. Psychophysiology. 2008;45(1):60-9. PubMed PMID: 17868262.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - MMN or no MMN: no magnitude of deviance effect on the MMN amplitude. AU - Horváth,János, AU - Czigler,István, AU - Jacobsen,Thomas, AU - Maess,Burkhard, AU - Schröger,Erich, AU - Winkler,István, Y1 - 2007/09/14/ PY - 2007/9/18/pubmed PY - 2008/4/10/medline PY - 2007/9/18/entrez SP - 60 EP - 9 JF - Psychophysiology JO - Psychophysiology VL - 45 IS - 1 N2 - Based on results showing that the "deviant-minus-standard" estimate of the mismatch negativity (MMN) amplitude increases with increasing amounts of deviance, it has been suggested that the MMN amplitude reflects the amount of difference between the neural representations of the standard and the deviant sound. However, the deviant-minus-standard waveform also includes an N1 difference. We tested the effects of the magnitude of deviance on MMN while minimizing this N1 confound. We found no significant magnitude of deviance effect on the genuine MMN amplitude. Thus we suggest that the average MMN amplitude does not reflect the difference between neural stimulus representations; rather it may index the percentage of detected deviants, each of which elicits an MMN response of uniform amplitude. These results are compatible with an explanation suggesting that MMN is involved in maintaining a neural representation of the auditory environment. SN - 0048-5772 UR - https://www.unboundmedicine.com/medline/citation/17868262/MMN_or_no_MMN:_no_magnitude_of_deviance_effect_on_the_MMN_amplitude_ L2 - https://doi.org/10.1111/j.1469-8986.2007.00599.x DB - PRIME DP - Unbound Medicine ER -