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Evaluation of new tumors in the setting of stage I/IIA mycosis fungoides.
Clin Lymphoma Myeloma. 2007 Jul; 7(7):480-5.CL

Abstract

Although mycosis fungoides is usually a slowly progressive indolent lymphoma, new cutaneous tumors might signal an aggressive phase of the disease. In order to provide appropriate therapeutic management when such tumors arise, it is important to make a correct diagnosis, which requires a bridge between clinical and histopathologic evaluations of the tumors. In this article, we describe 4 patients with preexisting diagnoses of mycosis fungoides, each of whom developed a distinct, new skin tumor. These tumors represented the following: mycosis fungoides without transformation, large-cell transformation of mycosis fungoides, lymphomatoid papulosis-associated CD30(+) lymphoproliferative disorder arising in a patient with mycosis fungoides, and a primary cutaneous CD30(+) lymphoproliferative disorder arising in a patient with mycosis fungoides. Each new and histologically distinct tumor was identified and treated according to a diagnosis concluded by careful clinicopathologic correlation, allowing for the selection of appropriate treatment in each case.

Authors+Show Affiliations

Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9190, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

17875239

Citation

Harrington, Cynthia R., et al. "Evaluation of New Tumors in the Setting of Stage I/IIA Mycosis Fungoides." Clinical Lymphoma & Myeloma, vol. 7, no. 7, 2007, pp. 480-5.
Harrington CR, Guillén DR, Pandya AG. Evaluation of new tumors in the setting of stage I/IIA mycosis fungoides. Clin Lymphoma Myeloma. 2007;7(7):480-5.
Harrington, C. R., Guillén, D. R., & Pandya, A. G. (2007). Evaluation of new tumors in the setting of stage I/IIA mycosis fungoides. Clinical Lymphoma & Myeloma, 7(7), 480-5.
Harrington CR, Guillén DR, Pandya AG. Evaluation of New Tumors in the Setting of Stage I/IIA Mycosis Fungoides. Clin Lymphoma Myeloma. 2007;7(7):480-5. PubMed PMID: 17875239.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of new tumors in the setting of stage I/IIA mycosis fungoides. AU - Harrington,Cynthia R, AU - Guillén,David R, AU - Pandya,Amit G, PY - 2007/9/19/pubmed PY - 2007/11/10/medline PY - 2007/9/19/entrez SP - 480 EP - 5 JF - Clinical lymphoma & myeloma JO - Clin Lymphoma Myeloma VL - 7 IS - 7 N2 - Although mycosis fungoides is usually a slowly progressive indolent lymphoma, new cutaneous tumors might signal an aggressive phase of the disease. In order to provide appropriate therapeutic management when such tumors arise, it is important to make a correct diagnosis, which requires a bridge between clinical and histopathologic evaluations of the tumors. In this article, we describe 4 patients with preexisting diagnoses of mycosis fungoides, each of whom developed a distinct, new skin tumor. These tumors represented the following: mycosis fungoides without transformation, large-cell transformation of mycosis fungoides, lymphomatoid papulosis-associated CD30(+) lymphoproliferative disorder arising in a patient with mycosis fungoides, and a primary cutaneous CD30(+) lymphoproliferative disorder arising in a patient with mycosis fungoides. Each new and histologically distinct tumor was identified and treated according to a diagnosis concluded by careful clinicopathologic correlation, allowing for the selection of appropriate treatment in each case. SN - 1557-9190 UR - https://www.unboundmedicine.com/medline/citation/17875239/Evaluation_of_new_tumors_in_the_setting_of_stage_I/IIA_mycosis_fungoides_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1557-9190(11)70095-6 DB - PRIME DP - Unbound Medicine ER -