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Efficacy of n-3 polyunsaturated fatty acids according to clinical characteristics of patients with recent myocardial infarction: insights from the GISSI-Prevenzione trial.
J Cardiovasc Med (Hagerstown). 2007 Sep; 8 Suppl 1:S34-7.JC

Abstract

The GISSI-Prevenzione trial established the efficacy of n-3 polyunsaturated fatty acids (PUFAs) for reducing mortality in patients after recent myocardial infarction. The generalisability of such results to clinical practice could vary according to other individual patient characteristics. We analysed the GISSI-Prevenzione database to assess whether other major risk factors, comorbidities, dietary habits, or medications could interact with the efficacy of n-3 PUFA treatment to reduce total mortality. We found no evidence that concomitant disease states, habits, or interventions altered the therapeutic benefit of n-3 PUFA consumption in survivors of recent myocardial infarction.

Authors+Show Affiliations

Consorzio Mario Negri Sud, Santa Maria Imbaro (CH), Italy. marchioli@negrisud.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17876196

Citation

Marchioli, Roberto, et al. "Efficacy of N-3 Polyunsaturated Fatty Acids According to Clinical Characteristics of Patients With Recent Myocardial Infarction: Insights From the GISSI-Prevenzione Trial." Journal of Cardiovascular Medicine (Hagerstown, Md.), vol. 8 Suppl 1, 2007, pp. S34-7.
Marchioli R, Marfisi RM, Borrelli G, et al. Efficacy of n-3 polyunsaturated fatty acids according to clinical characteristics of patients with recent myocardial infarction: insights from the GISSI-Prevenzione trial. J Cardiovasc Med (Hagerstown). 2007;8 Suppl 1:S34-7.
Marchioli, R., Marfisi, R. M., Borrelli, G., Chieffo, C., Franzosi, M. G., Levantesi, G., Maggioni, A. P., Nicolosi, G. L., Scarano, M., Silletta, M. G., Schweiger, C., Tavazzi, L., & Tognoni, G. (2007). Efficacy of n-3 polyunsaturated fatty acids according to clinical characteristics of patients with recent myocardial infarction: insights from the GISSI-Prevenzione trial. Journal of Cardiovascular Medicine (Hagerstown, Md.), 8 Suppl 1, S34-7.
Marchioli R, et al. Efficacy of N-3 Polyunsaturated Fatty Acids According to Clinical Characteristics of Patients With Recent Myocardial Infarction: Insights From the GISSI-Prevenzione Trial. J Cardiovasc Med (Hagerstown). 2007;8 Suppl 1:S34-7. PubMed PMID: 17876196.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of n-3 polyunsaturated fatty acids according to clinical characteristics of patients with recent myocardial infarction: insights from the GISSI-Prevenzione trial. AU - Marchioli,Roberto, AU - Marfisi,Rosa Maria, AU - Borrelli,Giovanna, AU - Chieffo,Carmelo, AU - Franzosi,Maria Grazia, AU - Levantesi,Giacomo, AU - Maggioni,Aldo Pietro, AU - Nicolosi,Gian Luigi, AU - Scarano,Marco, AU - Silletta,Maria Giuseppina, AU - Schweiger,Carlo, AU - Tavazzi,Luigi, AU - Tognoni,Gianni, PY - 2007/10/19/pubmed PY - 2008/1/25/medline PY - 2007/10/19/entrez SP - S34 EP - 7 JF - Journal of cardiovascular medicine (Hagerstown, Md.) JO - J Cardiovasc Med (Hagerstown) VL - 8 Suppl 1 N2 - The GISSI-Prevenzione trial established the efficacy of n-3 polyunsaturated fatty acids (PUFAs) for reducing mortality in patients after recent myocardial infarction. The generalisability of such results to clinical practice could vary according to other individual patient characteristics. We analysed the GISSI-Prevenzione database to assess whether other major risk factors, comorbidities, dietary habits, or medications could interact with the efficacy of n-3 PUFA treatment to reduce total mortality. We found no evidence that concomitant disease states, habits, or interventions altered the therapeutic benefit of n-3 PUFA consumption in survivors of recent myocardial infarction. SN - 1558-2027 UR - https://www.unboundmedicine.com/medline/citation/17876196/Efficacy_of_n_3_polyunsaturated_fatty_acids_according_to_clinical_characteristics_of_patients_with_recent_myocardial_infarction:_insights_from_the_GISSI_Prevenzione_trial_ L2 - http://dx.doi.org/10.2459/01.JCM.0000289271.80180.b6 DB - PRIME DP - Unbound Medicine ER -