Tags

Type your tag names separated by a space and hit enter

The prevalence and risk factors of reflux esophagitis among adult Chinese population in Taiwan.
J Clin Gastroenterol. 2007 Oct; 41(9):819-22.JC

Abstract

BACKGROUND

Risk factors of reflux esophagitis among Chinese in Taiwan are at present not clear and the role of Helicobacter pylori infection in the development of reflux esophagitis is still controversial.

GOALS

The aim of this study was to examine the prevalence of reflux esophagitis, and to identify risk factors associated with reflux esophagitis in a multivariate context and to evaluate if H. pylori is a predictive factor for reflux esophagitis.

STUDY

A total of 482 physical check-up subjects who underwent upper gastrointestinal endoscopy were investigated. The severity of esophagitis was evaluated by Los Angeles classification. H. pylori status was assessed by serology.

RESULTS

Twelve percent (58/482) demonstrated reflux esophagitis with 87% of grade A or B. Of those with reflux esophagitis, 48.3% had reflux symptoms whereas 17.4% of those with reflux symptoms had reflux esophagitis. Univariate analysis identified hiatal hernia, male sex, smoking, alcohol drinking, and overweight as risk factors associated with reflux esophagitis. Multivariable logistic regression showed that hiatal hernia [odds ratio (OR)=12.2, 95% confidence interval (CI)=5.0-29.9, P<0.0001], male sex (OR=4.2, 95% CI=1.9-9.0, P<0.001), and chronic obstructive pulmonary disease sufferers (OR=3.4, 95% CI=1.1-10.9, P<0.05) were 3 independent risk factors for development of reflux esophagitis.

CONCLUSIONS

The prevalence of reflux esophagitis in Taiwanese is 12% and most are mild grade and free from reflux symptoms. Hiatus hernia, male sex, and chronic obstructive pulmonary disease are 3 independent risk factors for development of reflux esophagitis. H. pylori infection did not protect subjects from reflux esophagitis.

Authors+Show Affiliations

Department of Medicine, Division of Gastroenterology, Taipei Veterans General Hospital, and National Yang-Ming University, Taipei, Taiwan, Republic of China.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17881927

Citation

Chen, Tseng-Shing, and Full-Young Chang. "The Prevalence and Risk Factors of Reflux Esophagitis Among Adult Chinese Population in Taiwan." Journal of Clinical Gastroenterology, vol. 41, no. 9, 2007, pp. 819-22.
Chen TS, Chang FY. The prevalence and risk factors of reflux esophagitis among adult Chinese population in Taiwan. J Clin Gastroenterol. 2007;41(9):819-22.
Chen, T. S., & Chang, F. Y. (2007). The prevalence and risk factors of reflux esophagitis among adult Chinese population in Taiwan. Journal of Clinical Gastroenterology, 41(9), 819-22.
Chen TS, Chang FY. The Prevalence and Risk Factors of Reflux Esophagitis Among Adult Chinese Population in Taiwan. J Clin Gastroenterol. 2007;41(9):819-22. PubMed PMID: 17881927.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The prevalence and risk factors of reflux esophagitis among adult Chinese population in Taiwan. AU - Chen,Tseng-Shing, AU - Chang,Full-Young, PY - 2007/9/21/pubmed PY - 2008/1/4/medline PY - 2007/9/21/entrez SP - 819 EP - 22 JF - Journal of clinical gastroenterology JO - J. Clin. Gastroenterol. VL - 41 IS - 9 N2 - BACKGROUND: Risk factors of reflux esophagitis among Chinese in Taiwan are at present not clear and the role of Helicobacter pylori infection in the development of reflux esophagitis is still controversial. GOALS: The aim of this study was to examine the prevalence of reflux esophagitis, and to identify risk factors associated with reflux esophagitis in a multivariate context and to evaluate if H. pylori is a predictive factor for reflux esophagitis. STUDY: A total of 482 physical check-up subjects who underwent upper gastrointestinal endoscopy were investigated. The severity of esophagitis was evaluated by Los Angeles classification. H. pylori status was assessed by serology. RESULTS: Twelve percent (58/482) demonstrated reflux esophagitis with 87% of grade A or B. Of those with reflux esophagitis, 48.3% had reflux symptoms whereas 17.4% of those with reflux symptoms had reflux esophagitis. Univariate analysis identified hiatal hernia, male sex, smoking, alcohol drinking, and overweight as risk factors associated with reflux esophagitis. Multivariable logistic regression showed that hiatal hernia [odds ratio (OR)=12.2, 95% confidence interval (CI)=5.0-29.9, P<0.0001], male sex (OR=4.2, 95% CI=1.9-9.0, P<0.001), and chronic obstructive pulmonary disease sufferers (OR=3.4, 95% CI=1.1-10.9, P<0.05) were 3 independent risk factors for development of reflux esophagitis. CONCLUSIONS: The prevalence of reflux esophagitis in Taiwanese is 12% and most are mild grade and free from reflux symptoms. Hiatus hernia, male sex, and chronic obstructive pulmonary disease are 3 independent risk factors for development of reflux esophagitis. H. pylori infection did not protect subjects from reflux esophagitis. SN - 0192-0790 UR - https://www.unboundmedicine.com/medline/citation/17881927/The_prevalence_and_risk_factors_of_reflux_esophagitis_among_adult_Chinese_population_in_Taiwan_ L2 - http://dx.doi.org/10.1097/01.mcg.0000225658.30803.79 DB - PRIME DP - Unbound Medicine ER -