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Eating disorders in adolescence: what is the role of hormone replacement therapy?
Curr Opin Obstet Gynecol 2007; 19(5):434-9CO

Abstract

PURPOSE OF REVIEW

To review the diagnostic criteria and clinical presentation of eating disorders in adolescence, to outline an approach to treatment, and examine evidence for prescribing hormone replacement therapy to increase bone mineral density in anorexia nervosa.

RECENT FINDINGS

Eating disorders are prevalent in adolescents and can present with amenorrhea and menstrual disturbances. Reduced bone mineral density leading to osteoporosis and increased fracture risk is a frequent, severe, and potentially irreversible complication of anorexia nervosa. The degree of bone mineral density reduction depends on the duration of amenorrhea and degree of malnutrition. Limited evidence supports the use of hormone replacement therapy to increase bone mineral density in adolescents with anorexia nervosa.

SUMMARY

In adolescents with amenorrhea or menstrual disturbances, the gynecologist should consider the possibility of an eating disorder. The diagnosis can be made on history and physical examination. If an eating disorder is suspected, the patient should be referred for evaluation and treatment. Support for the use of hormone replacement therapy to increase bone mineral density in adolescents with anorexia nervosa is limited, and its routine use should be discouraged. Weight restoration, calcium and vitamin D supplementation and the resumption of spontaneous menses is the mainstay of treatment.

Authors+Show Affiliations

Division of Adolescent Medicine, Lucile Packard Children's Hospital at Stanford, Mountain View, California 94040, USA. ngolden@stanford.edu

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

17885458

Citation

Golden, Neville H.. "Eating Disorders in Adolescence: what Is the Role of Hormone Replacement Therapy?" Current Opinion in Obstetrics & Gynecology, vol. 19, no. 5, 2007, pp. 434-9.
Golden NH. Eating disorders in adolescence: what is the role of hormone replacement therapy? Curr Opin Obstet Gynecol. 2007;19(5):434-9.
Golden, N. H. (2007). Eating disorders in adolescence: what is the role of hormone replacement therapy? Current Opinion in Obstetrics & Gynecology, 19(5), pp. 434-9.
Golden NH. Eating Disorders in Adolescence: what Is the Role of Hormone Replacement Therapy. Curr Opin Obstet Gynecol. 2007;19(5):434-9. PubMed PMID: 17885458.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Eating disorders in adolescence: what is the role of hormone replacement therapy? A1 - Golden,Neville H, PY - 2007/9/22/pubmed PY - 2008/1/11/medline PY - 2007/9/22/entrez SP - 434 EP - 9 JF - Current opinion in obstetrics & gynecology JO - Curr. Opin. Obstet. Gynecol. VL - 19 IS - 5 N2 - PURPOSE OF REVIEW: To review the diagnostic criteria and clinical presentation of eating disorders in adolescence, to outline an approach to treatment, and examine evidence for prescribing hormone replacement therapy to increase bone mineral density in anorexia nervosa. RECENT FINDINGS: Eating disorders are prevalent in adolescents and can present with amenorrhea and menstrual disturbances. Reduced bone mineral density leading to osteoporosis and increased fracture risk is a frequent, severe, and potentially irreversible complication of anorexia nervosa. The degree of bone mineral density reduction depends on the duration of amenorrhea and degree of malnutrition. Limited evidence supports the use of hormone replacement therapy to increase bone mineral density in adolescents with anorexia nervosa. SUMMARY: In adolescents with amenorrhea or menstrual disturbances, the gynecologist should consider the possibility of an eating disorder. The diagnosis can be made on history and physical examination. If an eating disorder is suspected, the patient should be referred for evaluation and treatment. Support for the use of hormone replacement therapy to increase bone mineral density in adolescents with anorexia nervosa is limited, and its routine use should be discouraged. Weight restoration, calcium and vitamin D supplementation and the resumption of spontaneous menses is the mainstay of treatment. SN - 1040-872X UR - https://www.unboundmedicine.com/medline/citation/17885458/Eating_disorders_in_adolescence:_what_is_the_role_of_hormone_replacement_therapy L2 - http://dx.doi.org/10.1097/GCO.0b013e3282eee384 DB - PRIME DP - Unbound Medicine ER -