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Major depression in individuals with chronic medical disorders: prevalence, correlates and association with health resource utilization, lost productivity and functional disability.
Gen Hosp Psychiatry. 2007 Sep-Oct; 29(5):409-16.GH

Abstract

OBJECTIVE

The objective of this study was to determine the prevalence and odds of major depression and the incremental effect of major depression on utilization, lost productivity and functional disability in individuals with common chronic medical disorders.

METHOD

Data on 30,801 adults from the 1999 National Health Interview Survey were analyzed. The 12-month prevalence and age/sex-adjusted odds of major depression were calculated for adults with hypertension (HTN), diabetes mellitus (DM), coronary artery disease (CAD), congestive heart failure (CHF), stroke or cerebrovascular accident (CVA), chronic obstructive pulmonary disease (COPD) and end-stage renal disease (ESRD). The association between chronic condition status (with and without major depression) and utilization, lost productivity and functional disability was determined by controlling for covariates.

RESULTS

The 12-month prevalence and age/sex-adjusted odds of major depression by chronic conditions were as follows: CHF, 7.9% [odds ratio (OR)=1.96]; HTN, 8.0% (OR=2.00); DM, 9.3% (OR=1.96); CAD, 9.3% (OR=2.30); CVA, 11.4% (OR=3.15); COPD, 15.4% (OR=3.21); ESRD, 17.0% (OR=3.56); any chronic condition, 8.8% (OR=2.61). Compared to adults without chronic conditions, those with chronic conditions plus major depression had greater odds of > or = 1 ambulatory visit [OR=1.50; 95% confidence interval (95% CI)=1.28, 1.77]; > or = 1 emergency room visit (OR=1.94; 95% CI=1.55, 2.45); and > or = 1 day in bed due to illness (OR=1.60; 95% CI=1.28, 2.00); and functional disability (OR=2.48; 95% CI=1.96, 3.15).

CONCLUSION

The 12-month prevalence and odds of major depression are high in individuals with chronic medical conditions, and major depression is associated with significant increases in utilization, lost productivity and functional disability.

Authors+Show Affiliations

Charleston VA TREP, Ralph H. Johnson VA Medical Center, Charleston, SC 29403, USA. egedel@musc.edu

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17888807

Citation

Egede, Leonard E.. "Major Depression in Individuals With Chronic Medical Disorders: Prevalence, Correlates and Association With Health Resource Utilization, Lost Productivity and Functional Disability." General Hospital Psychiatry, vol. 29, no. 5, 2007, pp. 409-16.
Egede LE. Major depression in individuals with chronic medical disorders: prevalence, correlates and association with health resource utilization, lost productivity and functional disability. Gen Hosp Psychiatry. 2007;29(5):409-16.
Egede, L. E. (2007). Major depression in individuals with chronic medical disorders: prevalence, correlates and association with health resource utilization, lost productivity and functional disability. General Hospital Psychiatry, 29(5), 409-16.
Egede LE. Major Depression in Individuals With Chronic Medical Disorders: Prevalence, Correlates and Association With Health Resource Utilization, Lost Productivity and Functional Disability. Gen Hosp Psychiatry. 2007;29(5):409-16. PubMed PMID: 17888807.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Major depression in individuals with chronic medical disorders: prevalence, correlates and association with health resource utilization, lost productivity and functional disability. A1 - Egede,Leonard E, PY - 2007/02/15/received PY - 2007/06/08/revised PY - 2007/06/08/accepted PY - 2007/9/25/pubmed PY - 2008/1/3/medline PY - 2007/9/25/entrez SP - 409 EP - 16 JF - General hospital psychiatry JO - Gen Hosp Psychiatry VL - 29 IS - 5 N2 - OBJECTIVE: The objective of this study was to determine the prevalence and odds of major depression and the incremental effect of major depression on utilization, lost productivity and functional disability in individuals with common chronic medical disorders. METHOD: Data on 30,801 adults from the 1999 National Health Interview Survey were analyzed. The 12-month prevalence and age/sex-adjusted odds of major depression were calculated for adults with hypertension (HTN), diabetes mellitus (DM), coronary artery disease (CAD), congestive heart failure (CHF), stroke or cerebrovascular accident (CVA), chronic obstructive pulmonary disease (COPD) and end-stage renal disease (ESRD). The association between chronic condition status (with and without major depression) and utilization, lost productivity and functional disability was determined by controlling for covariates. RESULTS: The 12-month prevalence and age/sex-adjusted odds of major depression by chronic conditions were as follows: CHF, 7.9% [odds ratio (OR)=1.96]; HTN, 8.0% (OR=2.00); DM, 9.3% (OR=1.96); CAD, 9.3% (OR=2.30); CVA, 11.4% (OR=3.15); COPD, 15.4% (OR=3.21); ESRD, 17.0% (OR=3.56); any chronic condition, 8.8% (OR=2.61). Compared to adults without chronic conditions, those with chronic conditions plus major depression had greater odds of > or = 1 ambulatory visit [OR=1.50; 95% confidence interval (95% CI)=1.28, 1.77]; > or = 1 emergency room visit (OR=1.94; 95% CI=1.55, 2.45); and > or = 1 day in bed due to illness (OR=1.60; 95% CI=1.28, 2.00); and functional disability (OR=2.48; 95% CI=1.96, 3.15). CONCLUSION: The 12-month prevalence and odds of major depression are high in individuals with chronic medical conditions, and major depression is associated with significant increases in utilization, lost productivity and functional disability. SN - 0163-8343 UR - https://www.unboundmedicine.com/medline/citation/17888807/Major_depression_in_individuals_with_chronic_medical_disorders:_prevalence_correlates_and_association_with_health_resource_utilization_lost_productivity_and_functional_disability_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0163-8343(07)00126-0 DB - PRIME DP - Unbound Medicine ER -