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Biotransformation of adrenosterone by filamentous fungus, Cunninghamella elegans.
Steroids. 2007 Dec; 72(14):923-9.S

Abstract

Microbial transformation of adrenosterone (1) by suspended-cell cultures of the filamentous fungus Cunninghamella elegans resulted in the production of five metabolites 2-6, which were identified as 9alpha-hydroxyadrenosterone (2), 11-ketotestosterone (3), 6beta-hydroxyadrenosterone (4), 9alpha-hydroxy-11-ketotestosterone (5), and 6beta-hydroxy-11-ketotestosterone (6). Structures of new metabolites 2, 5, and 6 were established by single-crystal X-ray diffraction analysis.

Authors+Show Affiliations

HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan. hej@cyber.net.pkNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17889091

Citation

Choudhary, Muhammad Iqbal, et al. "Biotransformation of Adrenosterone By Filamentous Fungus, Cunninghamella Elegans." Steroids, vol. 72, no. 14, 2007, pp. 923-9.
Choudhary MI, Khan NT, Musharraf SG, et al. Biotransformation of adrenosterone by filamentous fungus, Cunninghamella elegans. Steroids. 2007;72(14):923-9.
Choudhary, M. I., Khan, N. T., Musharraf, S. G., Anjum, S., & Atta-Ur-Rahman, . (2007). Biotransformation of adrenosterone by filamentous fungus, Cunninghamella elegans. Steroids, 72(14), 923-9.
Choudhary MI, et al. Biotransformation of Adrenosterone By Filamentous Fungus, Cunninghamella Elegans. Steroids. 2007;72(14):923-9. PubMed PMID: 17889091.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Biotransformation of adrenosterone by filamentous fungus, Cunninghamella elegans. AU - Choudhary,Muhammad Iqbal, AU - Khan,Naik T, AU - Musharraf,Syed G, AU - Anjum,Shazia, AU - Atta-Ur-Rahman,, Y1 - 2007/08/14/ PY - 2007/05/10/received PY - 2007/08/05/revised PY - 2007/08/08/accepted PY - 2007/9/25/pubmed PY - 2008/1/24/medline PY - 2007/9/25/entrez SP - 923 EP - 9 JF - Steroids JO - Steroids VL - 72 IS - 14 N2 - Microbial transformation of adrenosterone (1) by suspended-cell cultures of the filamentous fungus Cunninghamella elegans resulted in the production of five metabolites 2-6, which were identified as 9alpha-hydroxyadrenosterone (2), 11-ketotestosterone (3), 6beta-hydroxyadrenosterone (4), 9alpha-hydroxy-11-ketotestosterone (5), and 6beta-hydroxy-11-ketotestosterone (6). Structures of new metabolites 2, 5, and 6 were established by single-crystal X-ray diffraction analysis. SN - 0039-128X UR - https://www.unboundmedicine.com/medline/citation/17889091/Biotransformation_of_adrenosterone_by_filamentous_fungus_Cunninghamella_elegans_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0039-128X(07)00137-7 DB - PRIME DP - Unbound Medicine ER -