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Outcome of elderly patients undergoing primary percutaneous coronary intervention for acute ST-elevation myocardial infarction.
Catheter Cardiovasc Interv. 2007 Oct 01; 70(4):485-90.CC

Abstract

AIM

To investigate the outcome of primary percutaneous coronary interventions (PCI) in elderly patients (>/=>/=75 years) with ST-elevation myocardial infarction (STEMI).

METHODS AND RESULTS

Between 1995 and 2003, a total of 319 consecutive patients with acute ST-elevation myocardial infarction presenting within 6-12 hr after onset of symptoms were prospectively enrolled in a registry. Of 296 patients undergoing primary PCI, 40 patients were >/=>/=75 years old (group A) and 256 patients younger than 75 years (group B). Elderly patients presented with a lower ejection fraction (49 +/- 14% vs. 53 +/- 13%, P = 0.046) and a higher number of cardiovascular risk factors. PCI success was achieved in 80% (group A) and 91% (group B, P = 0.031), respectively with comparable door-to-balloon times (87 +/- 49 and 95 +/- 79 min, P = ns). Periprocedural complications in both groups were low and major adverse cardiac events (death, myocardial infarction, target vessel revascularization and cardiac rehospitalization) after 6 months amounted to 23% (group A) and 20% (group B, P = ns), respectively.

CONCLUSIONS

Clinical outcome of elderly patients (>/=>/=75 years) with acute STEMI is favorable and comparable with the middle-aged population. However, procedural success was significantly lower in elderly (80%) compared to younger patients (90%). Acute percutaneous coronary intervention appears to be safe and not associated with higher periprocedural complications, in elderly patients.

Authors+Show Affiliations

Department of Cardiology, University Hospital Bern, Bern, Switzerland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

17894363

Citation

Wenaweser, Peter, et al. "Outcome of Elderly Patients Undergoing Primary Percutaneous Coronary Intervention for Acute ST-elevation Myocardial Infarction." Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions, vol. 70, no. 4, 2007, pp. 485-90.
Wenaweser P, Ramser M, Windecker S, et al. Outcome of elderly patients undergoing primary percutaneous coronary intervention for acute ST-elevation myocardial infarction. Catheter Cardiovasc Interv. 2007;70(4):485-90.
Wenaweser, P., Ramser, M., Windecker, S., Lütolf, I., Meier, B., Seiler, C., Eberli, F. R., & Hess, O. M. (2007). Outcome of elderly patients undergoing primary percutaneous coronary intervention for acute ST-elevation myocardial infarction. Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions, 70(4), 485-90.
Wenaweser P, et al. Outcome of Elderly Patients Undergoing Primary Percutaneous Coronary Intervention for Acute ST-elevation Myocardial Infarction. Catheter Cardiovasc Interv. 2007 Oct 1;70(4):485-90. PubMed PMID: 17894363.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outcome of elderly patients undergoing primary percutaneous coronary intervention for acute ST-elevation myocardial infarction. AU - Wenaweser,Peter, AU - Ramser,Marianne, AU - Windecker,Stephan, AU - Lütolf,Indira, AU - Meier,Bernhard, AU - Seiler,Christian, AU - Eberli,Franz R, AU - Hess,Otto M, PY - 2007/9/27/pubmed PY - 2008/1/11/medline PY - 2007/9/27/entrez SP - 485 EP - 90 JF - Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions JO - Catheter Cardiovasc Interv VL - 70 IS - 4 N2 - AIM: To investigate the outcome of primary percutaneous coronary interventions (PCI) in elderly patients (>/=>/=75 years) with ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS: Between 1995 and 2003, a total of 319 consecutive patients with acute ST-elevation myocardial infarction presenting within 6-12 hr after onset of symptoms were prospectively enrolled in a registry. Of 296 patients undergoing primary PCI, 40 patients were >/=>/=75 years old (group A) and 256 patients younger than 75 years (group B). Elderly patients presented with a lower ejection fraction (49 +/- 14% vs. 53 +/- 13%, P = 0.046) and a higher number of cardiovascular risk factors. PCI success was achieved in 80% (group A) and 91% (group B, P = 0.031), respectively with comparable door-to-balloon times (87 +/- 49 and 95 +/- 79 min, P = ns). Periprocedural complications in both groups were low and major adverse cardiac events (death, myocardial infarction, target vessel revascularization and cardiac rehospitalization) after 6 months amounted to 23% (group A) and 20% (group B, P = ns), respectively. CONCLUSIONS: Clinical outcome of elderly patients (>/=>/=75 years) with acute STEMI is favorable and comparable with the middle-aged population. However, procedural success was significantly lower in elderly (80%) compared to younger patients (90%). Acute percutaneous coronary intervention appears to be safe and not associated with higher periprocedural complications, in elderly patients. SN - 1522-1946 UR - https://www.unboundmedicine.com/medline/citation/17894363/Outcome_of_elderly_patients_undergoing_primary_percutaneous_coronary_intervention_for_acute_ST_elevation_myocardial_infarction_ L2 - https://doi.org/10.1002/ccd.21128 DB - PRIME DP - Unbound Medicine ER -