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Range of ventricular dimensions and function by steady-state free precession cine MRI in repaired tetralogy of Fallot: right ventricular outflow tract patch vs. conduit repair.
J Magn Reson Imaging. 2007 Oct; 26(4):934-40.JM

Abstract

PURPOSE

To characterize the range of biventricular size and function evaluated by steady-state free precession (SSFP) cine magnetic resonance (MR) in a large cohort of patients with repaired tetralogy of Fallot (TOF), and to compare these measurements in those with a right ventricular outflow tract (RVOT) patch vs. a right ventricle-to-pulmonary artery (RV-PA) conduit.

MATERIALS AND METHODS

Analysis of ventricular size and function in 300 consecutive examinations in patients with repaired TOF evaluated by SSFP cine MR.

RESULTS

Of the 300 examinations performed in 256 patients, 69% had undergone repair with a RVOT patch and 31% with a RV-PA conduit. Compared to patients with RV-PA conduit, those with a RVOT patch had significantly more pulmonary regurgitation (PR) (38 +/- 17 vs. 23 +/- 16%, P < 0.0001), larger indexed RV end-diastolic volume (154 +/- 53 vs. 133 +/- 51 mL/m(2), P = 0.002), similar indexed end-systolic volume (80 +/- 39 vs. 74 +/- 46 mL/m(2), P = 0.31), higher ejection fraction (EF) (50 +/- 9 vs. 47 +/- 12%, P = 0.037), and lower mass-to-volume ratio (0.29 +/- 0.08 vs. 0.36 +/- 0.13, P < 0.0001). Pulmonary regurgitation fraction correlated positively with RV end-diastolic volume index in the RVOT patch group (r = 0.51, P < 0.0001) but not in the RV-PA conduit.

CONCLUSION

This study provides the range and distribution of biventricular size and function, and PR measured by MRI in a large contemporary cohort of patients with repaired TOF, and demonstrates important variations in RV mechanics between patients repaired with a RVOT patch and those with an RV-PA conduit.

Authors+Show Affiliations

Department of Cardiology, Children's Hospital Boston and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17896382

Citation

Samyn, Margaret M., et al. "Range of Ventricular Dimensions and Function By Steady-state Free Precession Cine MRI in Repaired Tetralogy of Fallot: Right Ventricular Outflow Tract Patch Vs. Conduit Repair." Journal of Magnetic Resonance Imaging : JMRI, vol. 26, no. 4, 2007, pp. 934-40.
Samyn MM, Powell AJ, Garg R, et al. Range of ventricular dimensions and function by steady-state free precession cine MRI in repaired tetralogy of Fallot: right ventricular outflow tract patch vs. conduit repair. J Magn Reson Imaging. 2007;26(4):934-40.
Samyn, M. M., Powell, A. J., Garg, R., Sena, L., & Geva, T. (2007). Range of ventricular dimensions and function by steady-state free precession cine MRI in repaired tetralogy of Fallot: right ventricular outflow tract patch vs. conduit repair. Journal of Magnetic Resonance Imaging : JMRI, 26(4), 934-40.
Samyn MM, et al. Range of Ventricular Dimensions and Function By Steady-state Free Precession Cine MRI in Repaired Tetralogy of Fallot: Right Ventricular Outflow Tract Patch Vs. Conduit Repair. J Magn Reson Imaging. 2007;26(4):934-40. PubMed PMID: 17896382.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Range of ventricular dimensions and function by steady-state free precession cine MRI in repaired tetralogy of Fallot: right ventricular outflow tract patch vs. conduit repair. AU - Samyn,Margaret M, AU - Powell,Andrew J, AU - Garg,Ruchira, AU - Sena,Laureen, AU - Geva,Tal, PY - 2007/9/27/pubmed PY - 2008/1/4/medline PY - 2007/9/27/entrez SP - 934 EP - 40 JF - Journal of magnetic resonance imaging : JMRI JO - J Magn Reson Imaging VL - 26 IS - 4 N2 - PURPOSE: To characterize the range of biventricular size and function evaluated by steady-state free precession (SSFP) cine magnetic resonance (MR) in a large cohort of patients with repaired tetralogy of Fallot (TOF), and to compare these measurements in those with a right ventricular outflow tract (RVOT) patch vs. a right ventricle-to-pulmonary artery (RV-PA) conduit. MATERIALS AND METHODS: Analysis of ventricular size and function in 300 consecutive examinations in patients with repaired TOF evaluated by SSFP cine MR. RESULTS: Of the 300 examinations performed in 256 patients, 69% had undergone repair with a RVOT patch and 31% with a RV-PA conduit. Compared to patients with RV-PA conduit, those with a RVOT patch had significantly more pulmonary regurgitation (PR) (38 +/- 17 vs. 23 +/- 16%, P < 0.0001), larger indexed RV end-diastolic volume (154 +/- 53 vs. 133 +/- 51 mL/m(2), P = 0.002), similar indexed end-systolic volume (80 +/- 39 vs. 74 +/- 46 mL/m(2), P = 0.31), higher ejection fraction (EF) (50 +/- 9 vs. 47 +/- 12%, P = 0.037), and lower mass-to-volume ratio (0.29 +/- 0.08 vs. 0.36 +/- 0.13, P < 0.0001). Pulmonary regurgitation fraction correlated positively with RV end-diastolic volume index in the RVOT patch group (r = 0.51, P < 0.0001) but not in the RV-PA conduit. CONCLUSION: This study provides the range and distribution of biventricular size and function, and PR measured by MRI in a large contemporary cohort of patients with repaired TOF, and demonstrates important variations in RV mechanics between patients repaired with a RVOT patch and those with an RV-PA conduit. SN - 1053-1807 UR - https://www.unboundmedicine.com/medline/citation/17896382/Range_of_ventricular_dimensions_and_function_by_steady_state_free_precession_cine_MRI_in_repaired_tetralogy_of_Fallot:_right_ventricular_outflow_tract_patch_vs__conduit_repair_ L2 - https://doi.org/10.1002/jmri.21094 DB - PRIME DP - Unbound Medicine ER -