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Functional genomics of wine yeast Saccharomyces cerevisiae.
Adv Food Nutr Res. 2007; 53:65-121.AF

Abstract

The application of genomic technologies to the analysis of wine strains of Saccharomyces cerevisiae has greatly enhanced our understanding of both native and laboratory strains of this important model eukaryote. Not only are differences in transcript, protein, and metabolite profiles being uncovered, but the heritable basis of these differences is also being elucidated. Although some challenges remain in the application of functional genomic technologies to commercial and native strains of S. cerevisiae, recent improvements, particularly in data analysis, have greatly extended the utility of these tools. Comparative analysis of laboratory and wine isolates is refining our understanding of the mechanisms of genome evolution. Genomic analysis of Saccharomyces in native environments is providing evidence of gene function to previously uncharacterized open reading frames and delineating the physiological parameters of ecological niche specialization and stress adaptation. The wealth of information being generated will soon be utilized to construct commercial stains with more desirable phenotypes, traits that will be designed to be genetically stable under commercial production conditions.

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Authors+Show Affiliations

Bisson LF
Department of Viticulture and Enology, University of California, Davis, California 95616, USA.
Karpel JE
No affiliation info available
Ramakrishnan V
No affiliation info available
Joseph L
No affiliation info available

MeSH

Adaptation, PhysiologicalBiodiversityDNA, FungalFood MicrobiologyGene Expression Regulation, FungalGenomeGenome, FungalGenomicsOpen Reading FramesProteomicsSaccharomyces cerevisiaeWine

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

17900497

Citation

Bisson, Linda F., et al. "Functional Genomics of Wine Yeast Saccharomyces Cerevisiae." Advances in Food and Nutrition Research, vol. 53, 2007, pp. 65-121.
Bisson LF, Karpel JE, Ramakrishnan V, et al. Functional genomics of wine yeast Saccharomyces cerevisiae. Adv Food Nutr Res. 2007;53:65-121.
Bisson, L. F., Karpel, J. E., Ramakrishnan, V., & Joseph, L. (2007). Functional genomics of wine yeast Saccharomyces cerevisiae. Advances in Food and Nutrition Research, 53, 65-121.
Bisson LF, et al. Functional Genomics of Wine Yeast Saccharomyces Cerevisiae. Adv Food Nutr Res. 2007;53:65-121. PubMed PMID: 17900497.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Functional genomics of wine yeast Saccharomyces cerevisiae. AU - Bisson,Linda F, AU - Karpel,Jonathan E, AU - Ramakrishnan,Vidhya, AU - Joseph,Lucy, PY - 2007/9/29/pubmed PY - 2008/1/23/medline PY - 2007/9/29/entrez SP - 65 EP - 121 JF - Advances in food and nutrition research JO - Adv Food Nutr Res VL - 53 N2 - The application of genomic technologies to the analysis of wine strains of Saccharomyces cerevisiae has greatly enhanced our understanding of both native and laboratory strains of this important model eukaryote. Not only are differences in transcript, protein, and metabolite profiles being uncovered, but the heritable basis of these differences is also being elucidated. Although some challenges remain in the application of functional genomic technologies to commercial and native strains of S. cerevisiae, recent improvements, particularly in data analysis, have greatly extended the utility of these tools. Comparative analysis of laboratory and wine isolates is refining our understanding of the mechanisms of genome evolution. Genomic analysis of Saccharomyces in native environments is providing evidence of gene function to previously uncharacterized open reading frames and delineating the physiological parameters of ecological niche specialization and stress adaptation. The wealth of information being generated will soon be utilized to construct commercial stains with more desirable phenotypes, traits that will be designed to be genetically stable under commercial production conditions. SN - 1043-4526 UR - https://www.unboundmedicine.com/medline/citation/17900497/Functional_genomics_of_wine_yeast_Saccharomyces_cerevisiae_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1043-4526(07)53003-2 DB - PRIME DP - Unbound Medicine ER -