TY - JOUR T1 - Migraineurs with patent foramen ovale have larger right-to-left shunt despite similar atrial septal characteristics. AU - Jesurum,Jill T, AU - Fuller,Cindy J, AU - Velez,Carles A, AU - Spencer,Merrill P, AU - Krabill,Kimberly A, AU - Likosky,William H, AU - Gray,William A, AU - Olsen,John V, AU - Reisman,Mark, Y1 - 2007/09/24/ PY - 2007/03/19/received PY - 2007/07/25/accepted PY - 2007/9/29/pubmed PY - 2008/1/5/medline PY - 2007/9/29/entrez SP - 209 EP - 16 JF - The journal of headache and pain JO - J Headache Pain VL - 8 IS - 4 N2 - The objective of the study was to assess differences in proportion of large right-to-left shunt (RLS) and atrial septal characteristics between migraineurs and non-migraineurs referred for transcatheter closure of patent foramen ovale (PF0). This retrospective study took place in a large metropolitan medical centre. The patients were migraineurs with aura (n=52), migraineurs without aura (n=19) and non-migraineurs (n=149). RLS was evaluated before closure using bilateral power m-mode transcranial Doppler at rest and after calibrated, sustained Valsalva manoeuvre, and graded with a validated 0-5 scale. Intracardiac echocardiography was used to assess atrial septal characteristics. Migraineurs had a higher proportion of large RLS (Grade IV or V) than nonmigraineurs at rest and after calibrated Valsalva (rest, p=0.04; Valsalva, p=0.01). Atrial septal characteristics were similar between groups. Migraine is associated with larger RLS at rest and strain; however migraine status does not predict PFO characteristics. SN - 1129-2369 UR - https://www.unboundmedicine.com/medline/citation/17901924/Migraineurs_with_patent_foramen_ovale_have_larger_right_to_left_shunt_despite_similar_atrial_septal_characteristics_ L2 - https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1007/s10194-007-0396-5 DB - PRIME DP - Unbound Medicine ER -