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The vitamin D receptor.
Dermatol Clin. 2007 Oct; 25(4):515-23, viii.DC

Abstract

The vitamin D endocrine system is known for its essential role in calcium homeostasis and bone metabolism, and induces cell differentiation, inhibits cell growth, controls other hormonal systems, and modulates the immune response. Vitamin D(3) is a prohormone that is taken up by diet or synthesized in ultraviolet radiation-exposed skin and metabolically converted to the active metabolite, 1alpha,25-dihydroxyvitamin D(3). This nuclear hormone binds with high affinity the nuclear receptor vitamin D receptor. More than 3000 synthetic analogs of 1alpha,25(OH)(2)D(3) are known. This review aims to provide an overview on vitamin D signaling from the skin perspective.

Authors+Show Affiliations

Life Sciences Research Unit, Universitè of Luxembourg, 162A, Avenue de la Faïencerie, L-1511 Luxembourg, Luxembourg. carsten.carlberg@uni.luNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

17903610

Citation

Carlberg, Carsten, and Sabine Seuter. "The Vitamin D Receptor." Dermatologic Clinics, vol. 25, no. 4, 2007, pp. 515-23, viii.
Carlberg C, Seuter S. The vitamin D receptor. Dermatol Clin. 2007;25(4):515-23, viii.
Carlberg, C., & Seuter, S. (2007). The vitamin D receptor. Dermatologic Clinics, 25(4), 515-23, viii.
Carlberg C, Seuter S. The Vitamin D Receptor. Dermatol Clin. 2007;25(4):515-23, viii. PubMed PMID: 17903610.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The vitamin D receptor. AU - Carlberg,Carsten, AU - Seuter,Sabine, PY - 2007/10/2/pubmed PY - 2007/12/15/medline PY - 2007/10/2/entrez SP - 515-23, viii JF - Dermatologic clinics JO - Dermatol Clin VL - 25 IS - 4 N2 - The vitamin D endocrine system is known for its essential role in calcium homeostasis and bone metabolism, and induces cell differentiation, inhibits cell growth, controls other hormonal systems, and modulates the immune response. Vitamin D(3) is a prohormone that is taken up by diet or synthesized in ultraviolet radiation-exposed skin and metabolically converted to the active metabolite, 1alpha,25-dihydroxyvitamin D(3). This nuclear hormone binds with high affinity the nuclear receptor vitamin D receptor. More than 3000 synthetic analogs of 1alpha,25(OH)(2)D(3) are known. This review aims to provide an overview on vitamin D signaling from the skin perspective. SN - 0733-8635 UR - https://www.unboundmedicine.com/medline/citation/17903610/The_vitamin_D_receptor_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0733-8635(07)00062-9 DB - PRIME DP - Unbound Medicine ER -