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Relationship between visual hallucinations and REM sleep behavior disorder in patients with Parkinson's disease.
Clin Neurol Neurosurg. 2007 Dec; 109(10):862-7.CN

Abstract

OBJECTIVES

REM sleep behavior disorder (RBD) has been documented to precede or to co-occur with Parkinson's disease (PD). Parkinson's disease is one of the most common neurological conditions associated with visual hallucinations. Cognitive dysfunction is present in PD, even at the early stages of these diseases. In this study we aimed to investigate the relationship between visual hallucinations and RBD in patients with idiopathic Parkinson's disease (IPD). Additionally, we evaluated the association of the cognition and the pattern of cognitive impairment with VHs and RBD, effects of factors like duration and severity of the disease and duration of levodopa usage.

PATIENTS AND METHODS

Seventy-nine patients, diagnosed as PD, were included the study and then, patients were divided into four groups; with RBD and VHs (group 1), with RBD but no VHs (group 2), with VHs but no RBD (group 3), without RBD and VHs (group 4). We compared each group with the others according to demographic characteristics and neuropsychological test scores.

RESULTS

Of all patients, in 46% (n=36) RBD and in 48% (n=38) VHs were observed. Our study established VHs in 58% of patients with RBD, and RBD in 55% of patients with VHs. However, due to a 40% incidence of VHs in patients without RBD, RBD and VHs were not found to be correlated. All of the neuropsychometric test scores did not reveal significant difference between groups.

CONCLUSION

Although it seems like there is a small association between RBD and VHs in our patients, it was not significant. Group 1 presented with significantly worse scores in UPDRS total scores and I, II subscores.

Authors+Show Affiliations

Department of Neurology, Haseki Educational and Research Hospital, Turkey.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17913346

Citation

Meral, Hasan, et al. "Relationship Between Visual Hallucinations and REM Sleep Behavior Disorder in Patients With Parkinson's Disease." Clinical Neurology and Neurosurgery, vol. 109, no. 10, 2007, pp. 862-7.
Meral H, Aydemir T, Ozer F, et al. Relationship between visual hallucinations and REM sleep behavior disorder in patients with Parkinson's disease. Clin Neurol Neurosurg. 2007;109(10):862-7.
Meral, H., Aydemir, T., Ozer, F., Ozturk, O., Ozben, S., Erol, C., Cetin, S., Hanoglu, L., Ozkayran, T., & Yilsen, M. (2007). Relationship between visual hallucinations and REM sleep behavior disorder in patients with Parkinson's disease. Clinical Neurology and Neurosurgery, 109(10), 862-7.
Meral H, et al. Relationship Between Visual Hallucinations and REM Sleep Behavior Disorder in Patients With Parkinson's Disease. Clin Neurol Neurosurg. 2007;109(10):862-7. PubMed PMID: 17913346.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relationship between visual hallucinations and REM sleep behavior disorder in patients with Parkinson's disease. AU - Meral,Hasan, AU - Aydemir,Tuba, AU - Ozer,Feriha, AU - Ozturk,Oya, AU - Ozben,Serkan, AU - Erol,Canan, AU - Cetin,Sibel, AU - Hanoglu,Lutfu, AU - Ozkayran,Tufan, AU - Yilsen,Meral, PY - 2007/03/26/received PY - 2007/08/15/revised PY - 2007/08/21/accepted PY - 2007/10/5/pubmed PY - 2008/1/10/medline PY - 2007/10/5/entrez SP - 862 EP - 7 JF - Clinical neurology and neurosurgery JO - Clin Neurol Neurosurg VL - 109 IS - 10 N2 - OBJECTIVES: REM sleep behavior disorder (RBD) has been documented to precede or to co-occur with Parkinson's disease (PD). Parkinson's disease is one of the most common neurological conditions associated with visual hallucinations. Cognitive dysfunction is present in PD, even at the early stages of these diseases. In this study we aimed to investigate the relationship between visual hallucinations and RBD in patients with idiopathic Parkinson's disease (IPD). Additionally, we evaluated the association of the cognition and the pattern of cognitive impairment with VHs and RBD, effects of factors like duration and severity of the disease and duration of levodopa usage. PATIENTS AND METHODS: Seventy-nine patients, diagnosed as PD, were included the study and then, patients were divided into four groups; with RBD and VHs (group 1), with RBD but no VHs (group 2), with VHs but no RBD (group 3), without RBD and VHs (group 4). We compared each group with the others according to demographic characteristics and neuropsychological test scores. RESULTS: Of all patients, in 46% (n=36) RBD and in 48% (n=38) VHs were observed. Our study established VHs in 58% of patients with RBD, and RBD in 55% of patients with VHs. However, due to a 40% incidence of VHs in patients without RBD, RBD and VHs were not found to be correlated. All of the neuropsychometric test scores did not reveal significant difference between groups. CONCLUSION: Although it seems like there is a small association between RBD and VHs in our patients, it was not significant. Group 1 presented with significantly worse scores in UPDRS total scores and I, II subscores. SN - 0303-8467 UR - https://www.unboundmedicine.com/medline/citation/17913346/Relationship_between_visual_hallucinations_and_REM_sleep_behavior_disorder_in_patients_with_Parkinson's_disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0303-8467(07)00236-3 DB - PRIME DP - Unbound Medicine ER -