Protective role of nordihydroguaiaretic acid (NDGA) against the genotoxic damage induced by ethynodiol diacetate in human lymphocytes in vitro.J Environ Biol. 2007 Apr; 28(2):279-82.JE
Abstract
Antioxidants and plant products are reported to reduce the genotoxic damage of steroids. In our present study we have tested different dosages of nordihydroguaiaretic acid (NDGA) against the genotoxic damage induced by ethynodiol diacetate in the presence of S9 mix. Treatments with nordihydroguaiaretic acid (NDGA) results in the reduction of the genotoxic damage. A significant decrease was observed at all the tested doses of NDGA in sister chromatic exchanges of number of abnormal cells. The results suggest a protective role of NDGA against the genotoxic damage.
MeSH
Pub Type(s)
Journal Article
Research Support, Non-U.S. Gov't
Language
eng
PubMed ID
17915765
Citation
Siddique, Yasir Hasan, et al. "Protective Role of Nordihydroguaiaretic Acid (NDGA) Against the Genotoxic Damage Induced By Ethynodiol Diacetate in Human Lymphocytes in Vitro." Journal of Environmental Biology, vol. 28, no. 2, 2007, pp. 279-82.
Siddique YH, Ara G, Beg T, et al. Protective role of nordihydroguaiaretic acid (NDGA) against the genotoxic damage induced by ethynodiol diacetate in human lymphocytes in vitro. J Environ Biol. 2007;28(2):279-82.
Siddique, Y. H., Ara, G., Beg, T., & Afzal, M. (2007). Protective role of nordihydroguaiaretic acid (NDGA) against the genotoxic damage induced by ethynodiol diacetate in human lymphocytes in vitro. Journal of Environmental Biology, 28(2), 279-82.
Siddique YH, et al. Protective Role of Nordihydroguaiaretic Acid (NDGA) Against the Genotoxic Damage Induced By Ethynodiol Diacetate in Human Lymphocytes in Vitro. J Environ Biol. 2007;28(2):279-82. PubMed PMID: 17915765.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Protective role of nordihydroguaiaretic acid (NDGA) against the genotoxic damage induced by ethynodiol diacetate in human lymphocytes in vitro.
AU - Siddique,Yasir Hasan,
AU - Ara,Gulshan,
AU - Beg,Tanveer,
AU - Afzal,Mohammad,
PY - 2007/10/6/pubmed
PY - 2008/1/16/medline
PY - 2007/10/6/entrez
SP - 279
EP - 82
JF - Journal of environmental biology
JO - J Environ Biol
VL - 28
IS - 2
N2 - Antioxidants and plant products are reported to reduce the genotoxic damage of steroids. In our present study we have tested different dosages of nordihydroguaiaretic acid (NDGA) against the genotoxic damage induced by ethynodiol diacetate in the presence of S9 mix. Treatments with nordihydroguaiaretic acid (NDGA) results in the reduction of the genotoxic damage. A significant decrease was observed at all the tested doses of NDGA in sister chromatic exchanges of number of abnormal cells. The results suggest a protective role of NDGA against the genotoxic damage.
SN - 0254-8704
UR - https://www.unboundmedicine.com/medline/citation/17915765/Protective_role_of_nordihydroguaiaretic_acid__NDGA__against_the_genotoxic_damage_induced_by_ethynodiol_diacetate_in_human_lymphocytes_in_vitro_
DB - PRIME
DP - Unbound Medicine
ER -