Tags

Type your tag names separated by a space and hit enter

Anti-inflammatory effects of low-level laser therapy (LLLT) with two different red wavelengths (660 nm and 684 nm) in carrageenan-induced rat paw edema.
J Photochem Photobiol B. 2007 Nov 12; 89(1):50-5.JP

Abstract

It has been suggested that low-level laser therapy (LLLT) can modulate inflammatory processes. The aim of this experiment was to investigate what effects red laser irradiation with two different wavelengths (660 nm and 684 nm) on carrageenan-induced rat paw edema and histology. Thirty two male Wistar rats were randomly divided into four groups. One group received a sterile saline injection, while inflammation was induced by a sub-plantar injection of carrageenan (1 mg/paw) in the three other groups. After 1 h, LLLT was administered to the paw in two of the carrageenan-injected groups. Continuous wave 660 nm and 684 nm red lasers respectively with mean optical outputs of 30 mW and doses of 7.5 J/cm(2) were used. The 660 nm and 684 nm laser groups developed significantly (p<0.01) less edema (0.58 ml [SE+/-0.17] ml and 0.76 ml [SE+/-0.10] respectively) than the control group (1.67 ml [SE+/-0.19]) at 4h after injections. Similarly, both laser groups showed a significantly lower number of inflammatory cells in the muscular and conjunctive sub-plantar tissues than the control group. We conclude that both 660 nm and 684 nm red wavelengths of LLLT are effective in reducing edema formation and inflammatory cell migration when a dose of 7.5 J/cm(2) is used.

Authors+Show Affiliations

Instituto de Pesquisa & Desenvolvimento, IP&D, Universidade do Vale do Paraíba, UNIVAP, Av. Shishima Hifumi, 2911, CEP: 12244-000 São José dos Campos, SP, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17920925

Citation

Albertini, R, et al. "Anti-inflammatory Effects of Low-level Laser Therapy (LLLT) With Two Different Red Wavelengths (660 Nm and 684 Nm) in Carrageenan-induced Rat Paw Edema." Journal of Photochemistry and Photobiology. B, Biology, vol. 89, no. 1, 2007, pp. 50-5.
Albertini R, Villaverde AB, Aimbire F, et al. Anti-inflammatory effects of low-level laser therapy (LLLT) with two different red wavelengths (660 nm and 684 nm) in carrageenan-induced rat paw edema. J Photochem Photobiol B. 2007;89(1):50-5.
Albertini, R., Villaverde, A. B., Aimbire, F., Salgado, M. A., Bjordal, J. M., Alves, L. P., Munin, E., & Costa, M. S. (2007). Anti-inflammatory effects of low-level laser therapy (LLLT) with two different red wavelengths (660 nm and 684 nm) in carrageenan-induced rat paw edema. Journal of Photochemistry and Photobiology. B, Biology, 89(1), 50-5.
Albertini R, et al. Anti-inflammatory Effects of Low-level Laser Therapy (LLLT) With Two Different Red Wavelengths (660 Nm and 684 Nm) in Carrageenan-induced Rat Paw Edema. J Photochem Photobiol B. 2007 Nov 12;89(1):50-5. PubMed PMID: 17920925.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anti-inflammatory effects of low-level laser therapy (LLLT) with two different red wavelengths (660 nm and 684 nm) in carrageenan-induced rat paw edema. AU - Albertini,R, AU - Villaverde,A B, AU - Aimbire,F, AU - Salgado,M A C, AU - Bjordal,J M, AU - Alves,L P, AU - Munin,E, AU - Costa,M S, Y1 - 2007/09/06/ PY - 2007/01/18/received PY - 2007/08/21/revised PY - 2007/08/28/accepted PY - 2007/10/9/pubmed PY - 2008/1/10/medline PY - 2007/10/9/entrez SP - 50 EP - 5 JF - Journal of photochemistry and photobiology. B, Biology JO - J Photochem Photobiol B VL - 89 IS - 1 N2 - It has been suggested that low-level laser therapy (LLLT) can modulate inflammatory processes. The aim of this experiment was to investigate what effects red laser irradiation with two different wavelengths (660 nm and 684 nm) on carrageenan-induced rat paw edema and histology. Thirty two male Wistar rats were randomly divided into four groups. One group received a sterile saline injection, while inflammation was induced by a sub-plantar injection of carrageenan (1 mg/paw) in the three other groups. After 1 h, LLLT was administered to the paw in two of the carrageenan-injected groups. Continuous wave 660 nm and 684 nm red lasers respectively with mean optical outputs of 30 mW and doses of 7.5 J/cm(2) were used. The 660 nm and 684 nm laser groups developed significantly (p<0.01) less edema (0.58 ml [SE+/-0.17] ml and 0.76 ml [SE+/-0.10] respectively) than the control group (1.67 ml [SE+/-0.19]) at 4h after injections. Similarly, both laser groups showed a significantly lower number of inflammatory cells in the muscular and conjunctive sub-plantar tissues than the control group. We conclude that both 660 nm and 684 nm red wavelengths of LLLT are effective in reducing edema formation and inflammatory cell migration when a dose of 7.5 J/cm(2) is used. SN - 1011-1344 UR - https://www.unboundmedicine.com/medline/citation/17920925/Anti_inflammatory_effects_of_low_level_laser_therapy__LLLT__with_two_different_red_wavelengths__660_nm_and_684_nm__in_carrageenan_induced_rat_paw_edema_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1011-1344(07)00127-3 DB - PRIME DP - Unbound Medicine ER -