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[Treatment of migraine].
Dtsch Med Wochenschr. 2007 Oct; 132(41):2153-8.DM

Abstract

Migraine attacks are characterized as unilateral and pulsating headache with autonomic features. In about 15 % of Migraine patients the attacks are accompanied by, mostly visual, transient focal neurologic disturbances, the migraine aura. Migraine attacks of mild or moderate intensity should initially be treated with non-steroidal anti-inflammatory drugs (NSAID). A combination with prokinetic and antiemetic drugs like metoclopramide or domperidone has proved to relieve nausea and increase efficacy of the analgesic drugs. In case of severe attacks or lack of treatment efficacy the migraine attacks should be treated with 5-HT (1B/1D) receptor agonists (triptans). Patients that suffer under very frequent and/or very severe migraine attacks should receive a prophylactic treatment. Prophylactic drugs of first choice are Betablockers (Propranolol and Metoprolol), Topiramate and Flunarizine. Prophylactic treatment should be administered over a period of at least 6 - 12 months.

Authors+Show Affiliations

Neurologische Klinik und Poliklinik, Charité Universitätsmedizin Berlin, Berlin, Germany.No affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

ger

PubMed ID

17924297

Citation

Hoffmann, J, and U Reuter. "[Treatment of Migraine]." Deutsche Medizinische Wochenschrift (1946), vol. 132, no. 41, 2007, pp. 2153-8.
Hoffmann J, Reuter U. [Treatment of migraine]. Dtsch Med Wochenschr. 2007;132(41):2153-8.
Hoffmann, J., & Reuter, U. (2007). [Treatment of migraine]. Deutsche Medizinische Wochenschrift (1946), 132(41), 2153-8.
Hoffmann J, Reuter U. [Treatment of Migraine]. Dtsch Med Wochenschr. 2007;132(41):2153-8. PubMed PMID: 17924297.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Treatment of migraine]. AU - Hoffmann,J, AU - Reuter,U, PY - 2007/10/10/pubmed PY - 2007/10/13/medline PY - 2007/10/10/entrez SP - 2153 EP - 8 JF - Deutsche medizinische Wochenschrift (1946) JO - Dtsch. Med. Wochenschr. VL - 132 IS - 41 N2 - Migraine attacks are characterized as unilateral and pulsating headache with autonomic features. In about 15 % of Migraine patients the attacks are accompanied by, mostly visual, transient focal neurologic disturbances, the migraine aura. Migraine attacks of mild or moderate intensity should initially be treated with non-steroidal anti-inflammatory drugs (NSAID). A combination with prokinetic and antiemetic drugs like metoclopramide or domperidone has proved to relieve nausea and increase efficacy of the analgesic drugs. In case of severe attacks or lack of treatment efficacy the migraine attacks should be treated with 5-HT (1B/1D) receptor agonists (triptans). Patients that suffer under very frequent and/or very severe migraine attacks should receive a prophylactic treatment. Prophylactic drugs of first choice are Betablockers (Propranolol and Metoprolol), Topiramate and Flunarizine. Prophylactic treatment should be administered over a period of at least 6 - 12 months. SN - 1439-4413 UR - https://www.unboundmedicine.com/medline/citation/17924297/[Treatment_of_migraine]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2007-985657 DB - PRIME DP - Unbound Medicine ER -
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