Tags

Type your tag names separated by a space and hit enter

Calcium, vitamin D, and dairy product intake and prostate cancer risk: the Multiethnic Cohort Study.
Am J Epidemiol 2007; 166(11):1259-69AJ

Abstract

High intakes of calcium and dairy products have been suggested to be related to prostate cancer risk. Such associations were examined in the Multiethnic Cohort Study (1993-2002) among 82,483 men who completed a detailed quantitative food frequency questionnaire. During a mean follow-up of 8 years, 4,404 total cases of prostate cancer were identified. In Cox proportional hazards models, no association was found between calcium and vitamin D intake and total, advanced, or high-grade prostate cancer risk, whether for total intake, intake from foods, or intake from supplements, among all male participants or among nonusers of supplemental calcium. No association of calcium or vitamin D intake was seen across racial/ethnic groups. In analyses of food groups, dairy product and total milk consumption were not associated with prostate cancer risk. However, low-/nonfat milk was related to an increased risk and whole milk to a decreased risk of total prostate cancer; after stratification, these effects were limited to localized or low-grade tumors. Although the findings from this study do not support an association between the intakes of calcium and vitamin D and prostate cancer risk, they do suggest that an association with milk consumption may vary by fat content, particularly for early forms of this cancer.

Authors+Show Affiliations

Cancer Epidemiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA. spark@crch.hawaii.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

17925283

Citation

Park, Song-Yi, et al. "Calcium, Vitamin D, and Dairy Product Intake and Prostate Cancer Risk: the Multiethnic Cohort Study." American Journal of Epidemiology, vol. 166, no. 11, 2007, pp. 1259-69.
Park SY, Murphy SP, Wilkens LR, et al. Calcium, vitamin D, and dairy product intake and prostate cancer risk: the Multiethnic Cohort Study. Am J Epidemiol. 2007;166(11):1259-69.
Park, S. Y., Murphy, S. P., Wilkens, L. R., Stram, D. O., Henderson, B. E., & Kolonel, L. N. (2007). Calcium, vitamin D, and dairy product intake and prostate cancer risk: the Multiethnic Cohort Study. American Journal of Epidemiology, 166(11), pp. 1259-69.
Park SY, et al. Calcium, Vitamin D, and Dairy Product Intake and Prostate Cancer Risk: the Multiethnic Cohort Study. Am J Epidemiol. 2007 Dec 1;166(11):1259-69. PubMed PMID: 17925283.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Calcium, vitamin D, and dairy product intake and prostate cancer risk: the Multiethnic Cohort Study. AU - Park,Song-Yi, AU - Murphy,Suzanne P, AU - Wilkens,Lynne R, AU - Stram,Daniel O, AU - Henderson,Brian E, AU - Kolonel,Laurence N, Y1 - 2007/10/08/ PY - 2007/10/11/pubmed PY - 2007/12/14/medline PY - 2007/10/11/entrez SP - 1259 EP - 69 JF - American journal of epidemiology JO - Am. J. Epidemiol. VL - 166 IS - 11 N2 - High intakes of calcium and dairy products have been suggested to be related to prostate cancer risk. Such associations were examined in the Multiethnic Cohort Study (1993-2002) among 82,483 men who completed a detailed quantitative food frequency questionnaire. During a mean follow-up of 8 years, 4,404 total cases of prostate cancer were identified. In Cox proportional hazards models, no association was found between calcium and vitamin D intake and total, advanced, or high-grade prostate cancer risk, whether for total intake, intake from foods, or intake from supplements, among all male participants or among nonusers of supplemental calcium. No association of calcium or vitamin D intake was seen across racial/ethnic groups. In analyses of food groups, dairy product and total milk consumption were not associated with prostate cancer risk. However, low-/nonfat milk was related to an increased risk and whole milk to a decreased risk of total prostate cancer; after stratification, these effects were limited to localized or low-grade tumors. Although the findings from this study do not support an association between the intakes of calcium and vitamin D and prostate cancer risk, they do suggest that an association with milk consumption may vary by fat content, particularly for early forms of this cancer. SN - 1476-6256 UR - https://www.unboundmedicine.com/medline/citation/17925283/Calcium_vitamin_D_and_dairy_product_intake_and_prostate_cancer_risk:_the_Multiethnic_Cohort_Study_ L2 - https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/kwm269 DB - PRIME DP - Unbound Medicine ER -