Tags

Type your tag names separated by a space and hit enter

Hepatic venous pressure gradient does not correlate with the presence and the severity of portal hypertensive gastropathy in patients with liver cirrhosis.
J Gastrointestin Liver Dis. 2007 Sep; 16(3):273-7.JG

Abstract

BACKGROUND AND AIMS

To evaluate whether the hepatic venous pressure gradient (HVPG) differs between cirrhotic patients with severe portal hypertensive gastropathy (PHG) and those with mild or absent PHG.

METHODS

59 cirrhotic patients with portal hypertension underwent hepatic vein catheterisation. 44 patients (76%) had PHG (16 mild and 28 severe).

SETTING

tertiary care setting (Liver Unit, Internal Medicine).

RESULTS

HVPG values did not differ between the patients without PHG (21.6 +/- 10.1 mmHg) and those with PHG (18.6 +/- 9.1 mmHg), nor between those with mild (19.3 +/- 4.3 mmHg) or severe PHG (17.7 +/- 4.6 mmHg; p = 0.26). The overall prevalence of PHG and the proportion of patients with severe PHG did not differ regarding the Child Pugh classification. The etiology of the cirrhosis did not influence the HVPG. No correlations were found between HVPG values and Child Pugh score, age, platelet count, prothrombin time, bilirubin levels and ALT values. The HVPG did not differ between patients with small, medium or large esophageal varices, nor between subjects with or without gastric varices.

CONCLUSIONS

Our data show that PHG does not correlate with the degree of portal pressure, and that the prevalence and the severity of this condition are not influenced by the severity of underlying liver disease or by the size of varices.

Authors+Show Affiliations

Haemodynamic Unit, Marino General Hospital, Via XXIV Maggio, 00047 Marino, Rome, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article

Language

eng

PubMed ID

17925921

Citation

Bellis, Lia, et al. "Hepatic Venous Pressure Gradient Does Not Correlate With the Presence and the Severity of Portal Hypertensive Gastropathy in Patients With Liver Cirrhosis." Journal of Gastrointestinal and Liver Diseases : JGLD, vol. 16, no. 3, 2007, pp. 273-7.
Bellis L, Nicodemo S, Galossi A, et al. Hepatic venous pressure gradient does not correlate with the presence and the severity of portal hypertensive gastropathy in patients with liver cirrhosis. J Gastrointestin Liver Dis. 2007;16(3):273-7.
Bellis, L., Nicodemo, S., Galossi, A., Guarisco, R., Spilabotti, L., Durola, L., Dell'Unto, O., & Puoti, C. (2007). Hepatic venous pressure gradient does not correlate with the presence and the severity of portal hypertensive gastropathy in patients with liver cirrhosis. Journal of Gastrointestinal and Liver Diseases : JGLD, 16(3), 273-7.
Bellis L, et al. Hepatic Venous Pressure Gradient Does Not Correlate With the Presence and the Severity of Portal Hypertensive Gastropathy in Patients With Liver Cirrhosis. J Gastrointestin Liver Dis. 2007;16(3):273-7. PubMed PMID: 17925921.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hepatic venous pressure gradient does not correlate with the presence and the severity of portal hypertensive gastropathy in patients with liver cirrhosis. AU - Bellis,Lia, AU - Nicodemo,Sabino, AU - Galossi,Alessandra, AU - Guarisco,Riccardo, AU - Spilabotti,Lucia, AU - Durola,Laura, AU - Dell'Unto,Orlando, AU - Puoti,Claudio, PY - 2007/10/11/pubmed PY - 2007/12/7/medline PY - 2007/10/11/entrez SP - 273 EP - 7 JF - Journal of gastrointestinal and liver diseases : JGLD JO - J Gastrointestin Liver Dis VL - 16 IS - 3 N2 - BACKGROUND AND AIMS: To evaluate whether the hepatic venous pressure gradient (HVPG) differs between cirrhotic patients with severe portal hypertensive gastropathy (PHG) and those with mild or absent PHG. METHODS: 59 cirrhotic patients with portal hypertension underwent hepatic vein catheterisation. 44 patients (76%) had PHG (16 mild and 28 severe). SETTING: tertiary care setting (Liver Unit, Internal Medicine). RESULTS: HVPG values did not differ between the patients without PHG (21.6 +/- 10.1 mmHg) and those with PHG (18.6 +/- 9.1 mmHg), nor between those with mild (19.3 +/- 4.3 mmHg) or severe PHG (17.7 +/- 4.6 mmHg; p = 0.26). The overall prevalence of PHG and the proportion of patients with severe PHG did not differ regarding the Child Pugh classification. The etiology of the cirrhosis did not influence the HVPG. No correlations were found between HVPG values and Child Pugh score, age, platelet count, prothrombin time, bilirubin levels and ALT values. The HVPG did not differ between patients with small, medium or large esophageal varices, nor between subjects with or without gastric varices. CONCLUSIONS: Our data show that PHG does not correlate with the degree of portal pressure, and that the prevalence and the severity of this condition are not influenced by the severity of underlying liver disease or by the size of varices. SN - 1841-8724 UR - https://www.unboundmedicine.com/medline/citation/17925921/Hepatic_venous_pressure_gradient_does_not_correlate_with_the_presence_and_the_severity_of_portal_hypertensive_gastropathy_in_patients_with_liver_cirrhosis_ L2 - https://www.jgld.ro/jgld/index.php/jgld/article/view/2007.3.7 DB - PRIME DP - Unbound Medicine ER -