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Cholinesterase inhibitors: tremor and exacerbation of Parkinson's disease.
Prescrire Int. 2007 Oct; 16(91):197-8.PI

Abstract

(1) Three cholinesterase inhibitors are marketed in France for the treatment of Alzheimer's disease: donepezil, galantamine and rivastigmine. Tremor and dystonia are known adverse effects of cholinesterase inhibitors. (2) In patients with Parkinson's disease who have cognitive disorders, or in patients with Lewy body dementia, exacerbations of parkinsonism and tremor have been observed during treatment with cholinesterase inhibitors at normal doses. The disorders were reversible on withdrawal of the cholinesterase inhibitor. (3) Withdrawal of cholinesterase inhibitors should be considered if gait disorders, falls or parkinsonism occur or worsen during treatment.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17926835

Citation

"Cholinesterase Inhibitors: Tremor and Exacerbation of Parkinson's Disease." Prescrire International, vol. 16, no. 91, 2007, pp. 197-8.
Cholinesterase inhibitors: tremor and exacerbation of Parkinson's disease. Prescrire Int. 2007;16(91):197-8.
(2007). Cholinesterase inhibitors: tremor and exacerbation of Parkinson's disease. Prescrire International, 16(91), 197-8.
Cholinesterase Inhibitors: Tremor and Exacerbation of Parkinson's Disease. Prescrire Int. 2007;16(91):197-8. PubMed PMID: 17926835.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cholinesterase inhibitors: tremor and exacerbation of Parkinson's disease. PY - 2007/10/12/pubmed PY - 2007/10/30/medline PY - 2007/10/12/entrez SP - 197 EP - 8 JF - Prescrire international JO - Prescrire Int VL - 16 IS - 91 N2 - (1) Three cholinesterase inhibitors are marketed in France for the treatment of Alzheimer's disease: donepezil, galantamine and rivastigmine. Tremor and dystonia are known adverse effects of cholinesterase inhibitors. (2) In patients with Parkinson's disease who have cognitive disorders, or in patients with Lewy body dementia, exacerbations of parkinsonism and tremor have been observed during treatment with cholinesterase inhibitors at normal doses. The disorders were reversible on withdrawal of the cholinesterase inhibitor. (3) Withdrawal of cholinesterase inhibitors should be considered if gait disorders, falls or parkinsonism occur or worsen during treatment. SN - 1167-7422 UR - https://www.unboundmedicine.com/medline/citation/17926835/Cholinesterase_inhibitors:_tremor_and_exacerbation_of_Parkinson's_disease_ L2 - http://www.diseaseinfosearch.org/result/7178 DB - PRIME DP - Unbound Medicine ER -