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Targeted UV therapy in the treatment of psoriasis.
J Dermatolog Treat. 2008; 19(3):141-5.JD

Abstract

Ultraviolet (UV) light is an effective treatment for extensive psoriasis and some other inflammatory skin conditions. Because the predominant effect of UV is a local one (as opposed to a systemic effect on immunity), localized delivery of ultraviolet B radiation (UVB) may be a useful treatment for localized variants of psoriasis and other conditions. The article reviews the literature regarding use of localized UV therapy. A theoretical benefit of localized UV therapy is reduced toxicity compared with whole-body therapy. Practical benefits in psoriasis treatment include higher efficacy and more appealing cosmesis compared with topicals. The 308-nm excimer laser is effective for psoriasis with fewer UVB treatments and lower total UVB exposure than needed for total body UV treatment. Other methods of localized UV delivery include quartz lamps, hand-held home UV devices, and non-laser intense photo sources. Other conditions treated with localized UV include vitiligo and lichen planus. Localized UV therapy is a useful modality for the treatment of localized variants of psoriasis with growing use for other dermatologic diseases.

Authors+Show Affiliations

Center for Dermatology Research, Department of Dermatology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1071, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

17934935

Citation

Stein, Kevin R., et al. "Targeted UV Therapy in the Treatment of Psoriasis." The Journal of Dermatological Treatment, vol. 19, no. 3, 2008, pp. 141-5.
Stein KR, Pearce DJ, Feldman SR. Targeted UV therapy in the treatment of psoriasis. J Dermatolog Treat. 2008;19(3):141-5.
Stein, K. R., Pearce, D. J., & Feldman, S. R. (2008). Targeted UV therapy in the treatment of psoriasis. The Journal of Dermatological Treatment, 19(3), 141-5.
Stein KR, Pearce DJ, Feldman SR. Targeted UV Therapy in the Treatment of Psoriasis. J Dermatolog Treat. 2008;19(3):141-5. PubMed PMID: 17934935.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Targeted UV therapy in the treatment of psoriasis. AU - Stein,Kevin R, AU - Pearce,Daniel J, AU - Feldman,Steven R, PY - 2007/10/16/pubmed PY - 2008/10/10/medline PY - 2007/10/16/entrez SP - 141 EP - 5 JF - The Journal of dermatological treatment JO - J Dermatolog Treat VL - 19 IS - 3 N2 - Ultraviolet (UV) light is an effective treatment for extensive psoriasis and some other inflammatory skin conditions. Because the predominant effect of UV is a local one (as opposed to a systemic effect on immunity), localized delivery of ultraviolet B radiation (UVB) may be a useful treatment for localized variants of psoriasis and other conditions. The article reviews the literature regarding use of localized UV therapy. A theoretical benefit of localized UV therapy is reduced toxicity compared with whole-body therapy. Practical benefits in psoriasis treatment include higher efficacy and more appealing cosmesis compared with topicals. The 308-nm excimer laser is effective for psoriasis with fewer UVB treatments and lower total UVB exposure than needed for total body UV treatment. Other methods of localized UV delivery include quartz lamps, hand-held home UV devices, and non-laser intense photo sources. Other conditions treated with localized UV include vitiligo and lichen planus. Localized UV therapy is a useful modality for the treatment of localized variants of psoriasis with growing use for other dermatologic diseases. SN - 1471-1753 UR - https://www.unboundmedicine.com/medline/citation/17934935/Targeted_UV_therapy_in_the_treatment_of_psoriasis_ L2 - http://www.tandfonline.com/doi/full/10.1080/09546630701593465 DB - PRIME DP - Unbound Medicine ER -