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All-cause mortality and risk factors in a cohort of retired military male veterans, Xi'an, China: an 18-year follow up study.
BMC Public Health 2007; 7:290BP

Abstract

BACKGROUND

Risk factors of all-cause mortality have not been reported in Chinese retired military veterans. The objective of the study was to examine the risk factors and proportional mortality in a Chinese retired military male cohort.

METHODS

A total of 1268 retired military men aged 55 or older were examined physically and interviewed using a standard questionnaire in 1987. The cohort was followed up every two years and the study censored date was June30, 2005 with a follow-up of up to 18 years. Death certificates were obtained from hospitals and verified by two senior doctors. Data were entered (double entry) by Foxbase, and analysis was carried out by SAS for Windows 8.2. Multivariate Cox proportional hazard regression model was used to compute hazard ratio (HR) and 95% confidence interval (CI).

RESULTS

The total person-years of follow-up was 18766.28. Of the initial cohort of 1268 men, 491 had died, 748 were alive and 29 were lost to follow up. Adjusted mortality (adjusted for age, blood pressure, body mass index, cholesterol, triglycerides, alcohol, exercise, and existing disease) was 2,616 per 100,000 person years. The proportional mortality of cancer, vascular disease and Chronic Obstructive Pulmonary Disease (COPD) were 39.71%, 28.10% and 16.90% respectively. Multivariate analysis showed that age, cigarettes per day, systolic blood pressure, triglyceride, family history of diseases (hypertension, stroke and cancer), existing diseases (stroke, diabetes and cancer), body mass index, and age of starting smoking were associated with all-cause mortality, HR (95%CI) was1.083(1.062-1.104), 1.026(1.013-1.039), 1.009(1.003-1.015), 1.002(1.001-1.003), 1.330(1.005-1.759), 1.330(1.005-1.759), 1.444(1.103-1.890), 2.237(1.244-4.022), 1.462(1.042-2.051), 2.079(1.051-4.115), 0.963(0.931-0.996)and 0.988(0.978-0.999)respectively. Compared with never-smokers, current smokers had increased risks of total mortality [HR 1.369(1.083-1.731)], CHD [HR 1.805 (1.022-3.188)], and lung cancer [HR 2.939 (1.311-6.585)].

CONCLUSION

The three leading causes of diseases were cancer, CHD and stroke, and COPD. Aging, cigarette smoking, high systolic blood pressure, high triglyceride, family history of cancer, hypertension and stroke, existing cases recovering from stroke, diabetes and cancer, underweight, younger age of smoking were risk factors for all-cause mortality. Quitting cigarette smoking, maintaining normal blood pressure, triglyceride and weight are effect control strategies to prevent premature mortality in this military cohort.

Authors+Show Affiliations

Department of Epidemiology, College of Military Services and Statistics, Fourth Military Medical University, Xi'an, China. saixiaoyong@163.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17935623

Citation

Sai, Xiao Y., et al. "All-cause Mortality and Risk Factors in a Cohort of Retired Military Male Veterans, Xi'an, China: an 18-year Follow Up Study." BMC Public Health, vol. 7, 2007, p. 290.
Sai XY, He Y, Men K, et al. All-cause mortality and risk factors in a cohort of retired military male veterans, Xi'an, China: an 18-year follow up study. BMC Public Health. 2007;7:290.
Sai, X. Y., He, Y., Men, K., Wang, B., Huang, J. Y., Shi, Q. L., ... Yan, Y. P. (2007). All-cause mortality and risk factors in a cohort of retired military male veterans, Xi'an, China: an 18-year follow up study. BMC Public Health, 7, p. 290.
Sai XY, et al. All-cause Mortality and Risk Factors in a Cohort of Retired Military Male Veterans, Xi'an, China: an 18-year Follow Up Study. BMC Public Health. 2007 Oct 12;7:290. PubMed PMID: 17935623.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - All-cause mortality and risk factors in a cohort of retired military male veterans, Xi'an, China: an 18-year follow up study. AU - Sai,Xiao Y, AU - He,Yao, AU - Men,Ke, AU - Wang,Bo, AU - Huang,Jiu Y, AU - Shi,Qiu L, AU - Zhang,Lei, AU - Li,Liang S, AU - Choi,Bernard Ck, AU - Yan,Yong P, Y1 - 2007/10/12/ PY - 2007/02/10/received PY - 2007/10/12/accepted PY - 2007/10/16/pubmed PY - 2008/3/6/medline PY - 2007/10/16/entrez SP - 290 EP - 290 JF - BMC public health JO - BMC Public Health VL - 7 N2 - BACKGROUND: Risk factors of all-cause mortality have not been reported in Chinese retired military veterans. The objective of the study was to examine the risk factors and proportional mortality in a Chinese retired military male cohort. METHODS: A total of 1268 retired military men aged 55 or older were examined physically and interviewed using a standard questionnaire in 1987. The cohort was followed up every two years and the study censored date was June30, 2005 with a follow-up of up to 18 years. Death certificates were obtained from hospitals and verified by two senior doctors. Data were entered (double entry) by Foxbase, and analysis was carried out by SAS for Windows 8.2. Multivariate Cox proportional hazard regression model was used to compute hazard ratio (HR) and 95% confidence interval (CI). RESULTS: The total person-years of follow-up was 18766.28. Of the initial cohort of 1268 men, 491 had died, 748 were alive and 29 were lost to follow up. Adjusted mortality (adjusted for age, blood pressure, body mass index, cholesterol, triglycerides, alcohol, exercise, and existing disease) was 2,616 per 100,000 person years. The proportional mortality of cancer, vascular disease and Chronic Obstructive Pulmonary Disease (COPD) were 39.71%, 28.10% and 16.90% respectively. Multivariate analysis showed that age, cigarettes per day, systolic blood pressure, triglyceride, family history of diseases (hypertension, stroke and cancer), existing diseases (stroke, diabetes and cancer), body mass index, and age of starting smoking were associated with all-cause mortality, HR (95%CI) was1.083(1.062-1.104), 1.026(1.013-1.039), 1.009(1.003-1.015), 1.002(1.001-1.003), 1.330(1.005-1.759), 1.330(1.005-1.759), 1.444(1.103-1.890), 2.237(1.244-4.022), 1.462(1.042-2.051), 2.079(1.051-4.115), 0.963(0.931-0.996)and 0.988(0.978-0.999)respectively. Compared with never-smokers, current smokers had increased risks of total mortality [HR 1.369(1.083-1.731)], CHD [HR 1.805 (1.022-3.188)], and lung cancer [HR 2.939 (1.311-6.585)]. CONCLUSION: The three leading causes of diseases were cancer, CHD and stroke, and COPD. Aging, cigarette smoking, high systolic blood pressure, high triglyceride, family history of cancer, hypertension and stroke, existing cases recovering from stroke, diabetes and cancer, underweight, younger age of smoking were risk factors for all-cause mortality. Quitting cigarette smoking, maintaining normal blood pressure, triglyceride and weight are effect control strategies to prevent premature mortality in this military cohort. SN - 1471-2458 UR - https://www.unboundmedicine.com/medline/citation/17935623/All_cause_mortality_and_risk_factors_in_a_cohort_of_retired_military_male_veterans_Xi'an_China:_an_18_year_follow_up_study_ L2 - https://bmcpublichealth.biomedcentral.com/articles/10.1186/1471-2458-7-290 DB - PRIME DP - Unbound Medicine ER -