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Pregnancy outcomes in patients with sickle cell disease in Enugu, Nigeria.
Niger J Med. 2007 Jul-Sep; 16(3):227-30.NJ

Abstract

BACKGROUND

Pregnancy in patients with sickle cell disease (SCD) is associated with increased maternal and foetal morbidity and mortality. The objective of this study was to review the pregnancy outcomes in patients with SCD as seen at the University of Nigeria Teaching Hospital (UNTH), Enugu, South-eastern Nigeria.

METHODS

This is a retrospective study. The data extracted from the patients' case files include the age, parity, gestational age at booking and complications of disease and pregnancy during the antenatal period, labour and puerperium. Fetal outcomes were also reviewed.

RESULTS

During the 30-year period under study (1975-2004), only 10 pregnant women with sickle cell disease were documented to have been attended to. Pregnancies were characterized by high maternal and fetal morbidity and mortality. Maternal complications identified were maternal mortality, lobar pneumonia, HIV and recurrent malaria infections, candidiasis, bone pain crises, haemolytic crises, pseudotoxaemia and pre-eclampsia. Fetal complications included intra-uterine fetal deaths, still births, low birth weights, and breech presentation.

CONCLUSION

From this study, it seems that female SCD patients present more rarely with pregnancy in South-eastern compared to South-western Nigeria. However, the spectrum of complications seen is similar to that recorded in other studies.

Authors+Show Affiliations

Department of Haematology, University of Nigeria Teaching Hospital, Enugu, Nigeria. kcjsocheni@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17937158

Citation

Ocheni, S, et al. "Pregnancy Outcomes in Patients With Sickle Cell Disease in Enugu, Nigeria." Nigerian Journal of Medicine : Journal of the National Association of Resident Doctors of Nigeria, vol. 16, no. 3, 2007, pp. 227-30.
Ocheni S, Onah HE, Ibegbulam OG, et al. Pregnancy outcomes in patients with sickle cell disease in Enugu, Nigeria. Niger J Med. 2007;16(3):227-30.
Ocheni, S., Onah, H. E., Ibegbulam, O. G., & Eze, M. I. (2007). Pregnancy outcomes in patients with sickle cell disease in Enugu, Nigeria. Nigerian Journal of Medicine : Journal of the National Association of Resident Doctors of Nigeria, 16(3), 227-30.
Ocheni S, et al. Pregnancy Outcomes in Patients With Sickle Cell Disease in Enugu, Nigeria. Niger J Med. 2007 Jul-Sep;16(3):227-30. PubMed PMID: 17937158.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pregnancy outcomes in patients with sickle cell disease in Enugu, Nigeria. AU - Ocheni,S, AU - Onah,H E, AU - Ibegbulam,O G, AU - Eze,M I, PY - 2007/10/17/pubmed PY - 2007/11/14/medline PY - 2007/10/17/entrez SP - 227 EP - 30 JF - Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria JO - Niger J Med VL - 16 IS - 3 N2 - BACKGROUND: Pregnancy in patients with sickle cell disease (SCD) is associated with increased maternal and foetal morbidity and mortality. The objective of this study was to review the pregnancy outcomes in patients with SCD as seen at the University of Nigeria Teaching Hospital (UNTH), Enugu, South-eastern Nigeria. METHODS: This is a retrospective study. The data extracted from the patients' case files include the age, parity, gestational age at booking and complications of disease and pregnancy during the antenatal period, labour and puerperium. Fetal outcomes were also reviewed. RESULTS: During the 30-year period under study (1975-2004), only 10 pregnant women with sickle cell disease were documented to have been attended to. Pregnancies were characterized by high maternal and fetal morbidity and mortality. Maternal complications identified were maternal mortality, lobar pneumonia, HIV and recurrent malaria infections, candidiasis, bone pain crises, haemolytic crises, pseudotoxaemia and pre-eclampsia. Fetal complications included intra-uterine fetal deaths, still births, low birth weights, and breech presentation. CONCLUSION: From this study, it seems that female SCD patients present more rarely with pregnancy in South-eastern compared to South-western Nigeria. However, the spectrum of complications seen is similar to that recorded in other studies. SN - 1115-2613 UR - https://www.unboundmedicine.com/medline/citation/17937158/Pregnancy_outcomes_in_patients_with_sickle_cell_disease_in_Enugu_Nigeria_ L2 - http://www.diseaseinfosearch.org/result/5922 DB - PRIME DP - Unbound Medicine ER -