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The inhibitory effect of the components of Cornus officinalis on melanogenesis.
J Cosmet Sci. 2007 Sep-Oct; 58(5):505-17.JC

Abstract

Five known compounds were isolated from a Cornus officinalis 50% ethanol extract (C. officinalis extract) and a hot water extract. We investigated the photochemical and pharmacological active compounds of C. officinalis hot water extract and ethanol extract. We understood that C. officinalis is a medicinal plant with potent free-radical-scavenging activity not only against reactive oxygen species (H(2)O(2), superoxiside anion, hydroxyl radical, etc.) in a narrow sense, but also against many other free radicals (peroxynitrate, peroxyradical). It is estimated that the reduction effect with C. officinalis extract can block oxidative reaction on melanogenesis. Loganin and cornuside, the components in C. officinalis, showed a significant free-radical-scavenging activity and inhibitory effects on melanogenesis. We report to prove the inhibitory effect of UVB-induced pigmentation in C. officinalis extract through its radical scavenging activity.

Authors+Show Affiliations

Research & Development, Ichimaru Pharcos Co., Ltd., 318-1, Asagi, Motosu, Gifu 501-0475, Japan.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17938826

Citation

Nawa, Yasuhiko, et al. "The Inhibitory Effect of the Components of Cornus Officinalis On Melanogenesis." Journal of Cosmetic Science, vol. 58, no. 5, 2007, pp. 505-17.
Nawa Y, Endo J, Ohta T. The inhibitory effect of the components of Cornus officinalis on melanogenesis. J Cosmet Sci. 2007;58(5):505-17.
Nawa, Y., Endo, J., & Ohta, T. (2007). The inhibitory effect of the components of Cornus officinalis on melanogenesis. Journal of Cosmetic Science, 58(5), 505-17.
Nawa Y, Endo J, Ohta T. The Inhibitory Effect of the Components of Cornus Officinalis On Melanogenesis. J Cosmet Sci. 2007 Sep-Oct;58(5):505-17. PubMed PMID: 17938826.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The inhibitory effect of the components of Cornus officinalis on melanogenesis. AU - Nawa,Yasuhiko, AU - Endo,Junko, AU - Ohta,Tomihisa, PY - 2007/05/22/accepted PY - 2007/10/17/pubmed PY - 2008/2/19/medline PY - 2007/10/17/entrez SP - 505 EP - 17 JF - Journal of cosmetic science JO - J Cosmet Sci VL - 58 IS - 5 N2 - Five known compounds were isolated from a Cornus officinalis 50% ethanol extract (C. officinalis extract) and a hot water extract. We investigated the photochemical and pharmacological active compounds of C. officinalis hot water extract and ethanol extract. We understood that C. officinalis is a medicinal plant with potent free-radical-scavenging activity not only against reactive oxygen species (H(2)O(2), superoxiside anion, hydroxyl radical, etc.) in a narrow sense, but also against many other free radicals (peroxynitrate, peroxyradical). It is estimated that the reduction effect with C. officinalis extract can block oxidative reaction on melanogenesis. Loganin and cornuside, the components in C. officinalis, showed a significant free-radical-scavenging activity and inhibitory effects on melanogenesis. We report to prove the inhibitory effect of UVB-induced pigmentation in C. officinalis extract through its radical scavenging activity. SN - 1525-7886 UR - https://www.unboundmedicine.com/medline/citation/17938826/The_inhibitory_effect_of_the_components_of_Cornus_officinalis_on_melanogenesis_ DB - PRIME DP - Unbound Medicine ER -