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Image quality and radiation exposure at pulmonary CT angiography with 100- or 120-kVp protocol: prospective randomized study.
Radiology. 2007 Nov; 245(2):577-83.R

Abstract

PURPOSE

To prospectively compare 16-section multidetector computed tomography (CT) at 100 and 120 kVp for image quality and radiation dose.

MATERIALS AND METHODS

The study had institutional review board approval; written informed consent was obtained. Sixty patients were referred for evaluation of suspected pulmonary embolism with CT angiography. Patients were randomly assigned to a 100-kVp (n = 30; 17 men, 13 women; mean age, 66 years +/- 17 [standard deviation]; range, 19-89 years) or 120-kVp (n = 30; 15 men, 15 women; mean age, 62 years +/- 15; range, 28-86 years) protocol. Other scanning parameters were kept constant. Contrast medium was injected automatically with bolus tracking. Pulmonary vessel enhancement and image noise were quantified; signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Subjective vessel contrast was assessed by two radiologists in consensus. Effective dose was calculated on the basis of dose length product and volume CT dose index. Results of both protocols were compared by using the chi(2) test and Student t test.

RESULTS

The 100-kVp protocol had a nonsignificantly higher mean vessel attenuation than the 120-kVp protocol (386.8 HU +/- 130.1 vs 317.9 HU +/- 112.5; P = .56) and a nonsignificantly higher image noise (16.9 HU +/- 5.8 vs 13.7 HU +/- 6.2; P = .84), which resulted in almost identical SNR (25.3 +/- 11.7 vs 27.0 +/- 14.5; P = .37) and CNR (22.0 +/- 11.2 vs 22.9 +/- 13.1; P = .51). There was no significant difference in subjective image quality between protocols. Mean effective dose for the 100-kVp protocol was significantly lower than that for the 120-kVp protocol (1.37 mSv +/- 0.39 vs 2.44 mSv +/- 0.97; -44%; P < .001).

CONCLUSION

Reduction of kilovoltage from 120 to 100 kVp resulted in significant reduction of effective dose at pulmonary CT angiography, without significant loss of objective or subjective image quality.

Authors+Show Affiliations

Institute of Diagnostic Radiology, Interventional Radiology and Nuclear Medicine, BG Clinics Bergmannsheil, Ruhr-University of Bochum, Buerkle-de-la-Camp Platz 1, D-44789, Bochum, Germany. christoph.heyer@rub.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

17940308

Citation

Heyer, Christoph M., et al. "Image Quality and Radiation Exposure at Pulmonary CT Angiography With 100- or 120-kVp Protocol: Prospective Randomized Study." Radiology, vol. 245, no. 2, 2007, pp. 577-83.
Heyer CM, Mohr PS, Lemburg SP, et al. Image quality and radiation exposure at pulmonary CT angiography with 100- or 120-kVp protocol: prospective randomized study. Radiology. 2007;245(2):577-83.
Heyer, C. M., Mohr, P. S., Lemburg, S. P., Peters, S. A., & Nicolas, V. (2007). Image quality and radiation exposure at pulmonary CT angiography with 100- or 120-kVp protocol: prospective randomized study. Radiology, 245(2), 577-83.
Heyer CM, et al. Image Quality and Radiation Exposure at Pulmonary CT Angiography With 100- or 120-kVp Protocol: Prospective Randomized Study. Radiology. 2007;245(2):577-83. PubMed PMID: 17940308.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Image quality and radiation exposure at pulmonary CT angiography with 100- or 120-kVp protocol: prospective randomized study. AU - Heyer,Christoph M, AU - Mohr,Patrick S, AU - Lemburg,Stefan P, AU - Peters,Soeren A, AU - Nicolas,Volkmar, PY - 2007/10/18/pubmed PY - 2007/12/6/medline PY - 2007/10/18/entrez SP - 577 EP - 83 JF - Radiology JO - Radiology VL - 245 IS - 2 N2 - PURPOSE: To prospectively compare 16-section multidetector computed tomography (CT) at 100 and 120 kVp for image quality and radiation dose. MATERIALS AND METHODS: The study had institutional review board approval; written informed consent was obtained. Sixty patients were referred for evaluation of suspected pulmonary embolism with CT angiography. Patients were randomly assigned to a 100-kVp (n = 30; 17 men, 13 women; mean age, 66 years +/- 17 [standard deviation]; range, 19-89 years) or 120-kVp (n = 30; 15 men, 15 women; mean age, 62 years +/- 15; range, 28-86 years) protocol. Other scanning parameters were kept constant. Contrast medium was injected automatically with bolus tracking. Pulmonary vessel enhancement and image noise were quantified; signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Subjective vessel contrast was assessed by two radiologists in consensus. Effective dose was calculated on the basis of dose length product and volume CT dose index. Results of both protocols were compared by using the chi(2) test and Student t test. RESULTS: The 100-kVp protocol had a nonsignificantly higher mean vessel attenuation than the 120-kVp protocol (386.8 HU +/- 130.1 vs 317.9 HU +/- 112.5; P = .56) and a nonsignificantly higher image noise (16.9 HU +/- 5.8 vs 13.7 HU +/- 6.2; P = .84), which resulted in almost identical SNR (25.3 +/- 11.7 vs 27.0 +/- 14.5; P = .37) and CNR (22.0 +/- 11.2 vs 22.9 +/- 13.1; P = .51). There was no significant difference in subjective image quality between protocols. Mean effective dose for the 100-kVp protocol was significantly lower than that for the 120-kVp protocol (1.37 mSv +/- 0.39 vs 2.44 mSv +/- 0.97; -44%; P < .001). CONCLUSION: Reduction of kilovoltage from 120 to 100 kVp resulted in significant reduction of effective dose at pulmonary CT angiography, without significant loss of objective or subjective image quality. SN - 0033-8419 UR - https://www.unboundmedicine.com/medline/citation/17940308/Image_quality_and_radiation_exposure_at_pulmonary_CT_angiography_with_100__or_120_kVp_protocol:_prospective_randomized_study_ L2 - https://pubs.rsna.org/doi/10.1148/radiol.2452061919?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -