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Dietary fat and breast cancer risk in the Swedish women's lifestyle and health cohort.
Br J Cancer 2007; 97(11):1570-6BJ

Abstract

We investigated whether dietary intakes of total fat, monounsaturated fat (MUFA), polyunsaturated fat (PUFA) and saturated fat (SFA) were associated with breast cancer risk in a prospective cohort of 49 261 Swedish women (30-49 years at enrolment), which yielded 974 breast cancer cases by December 2005. Further, we evaluated if associations differed by oestrogen and/or progesterone receptor tumour status. Total fat, MUFA, PUFA or SFA were not associated with risk overall. However, women in the highest MUFA and PUFA quintile intake had a reduced breast cancer risk after age 50 years (hazard ratios: 95% confidence interval=0.45: 0.25-0.99 and 0.54: 0.35-0.85, respectively) compared to women in the lowest quintile. The associations did not differ by oestrogen or progesterone receptor status. Despite the negative findings, type of fat during premenopausal years may have later differential effects on risk.

Authors+Show Affiliations

Department of Medical Epidemiology and Biostatistics, Karolinska Institute, PO 281, Stockholm SE-171 77, Sweden. marie.lof@ki.seNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17940510

Citation

Löf, M, et al. "Dietary Fat and Breast Cancer Risk in the Swedish Women's Lifestyle and Health Cohort." British Journal of Cancer, vol. 97, no. 11, 2007, pp. 1570-6.
Löf M, Sandin S, Lagiou P, et al. Dietary fat and breast cancer risk in the Swedish women's lifestyle and health cohort. Br J Cancer. 2007;97(11):1570-6.
Löf, M., Sandin, S., Lagiou, P., Hilakivi-Clarke, L., Trichopoulos, D., Adami, H. O., & Weiderpass, E. (2007). Dietary fat and breast cancer risk in the Swedish women's lifestyle and health cohort. British Journal of Cancer, 97(11), pp. 1570-6.
Löf M, et al. Dietary Fat and Breast Cancer Risk in the Swedish Women's Lifestyle and Health Cohort. Br J Cancer. 2007 Dec 3;97(11):1570-6. PubMed PMID: 17940510.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary fat and breast cancer risk in the Swedish women's lifestyle and health cohort. AU - Löf,M, AU - Sandin,S, AU - Lagiou,P, AU - Hilakivi-Clarke,L, AU - Trichopoulos,D, AU - Adami,H-O, AU - Weiderpass,E, Y1 - 2007/10/16/ PY - 2007/10/18/pubmed PY - 2008/1/25/medline PY - 2007/10/18/entrez SP - 1570 EP - 6 JF - British journal of cancer JO - Br. J. Cancer VL - 97 IS - 11 N2 - We investigated whether dietary intakes of total fat, monounsaturated fat (MUFA), polyunsaturated fat (PUFA) and saturated fat (SFA) were associated with breast cancer risk in a prospective cohort of 49 261 Swedish women (30-49 years at enrolment), which yielded 974 breast cancer cases by December 2005. Further, we evaluated if associations differed by oestrogen and/or progesterone receptor tumour status. Total fat, MUFA, PUFA or SFA were not associated with risk overall. However, women in the highest MUFA and PUFA quintile intake had a reduced breast cancer risk after age 50 years (hazard ratios: 95% confidence interval=0.45: 0.25-0.99 and 0.54: 0.35-0.85, respectively) compared to women in the lowest quintile. The associations did not differ by oestrogen or progesterone receptor status. Despite the negative findings, type of fat during premenopausal years may have later differential effects on risk. SN - 0007-0920 UR - https://www.unboundmedicine.com/medline/citation/17940510/Dietary_fat_and_breast_cancer_risk_in_the_Swedish_women's_lifestyle_and_health_cohort_ L2 - http://dx.doi.org/10.1038/sj.bjc.6604033 DB - PRIME DP - Unbound Medicine ER -