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Egg labeling methods for gastric emptying scintigraphy are not equivalent in producing a stable solid meal.
J Nucl Med. 2007 Nov; 48(11):1897-900.JN

Abstract

A wide range of radiolabeled test meals have been used for gastric emptying scintigraphy. The purpose of this study was to test whether (99m)Tc-sulfur colloid-labeled liquid egg white is as stable as 2 fresh whole eggs labeled with (99m)Tc-sulfur colloid and whether the cooking method is important.

METHODS

Whole eggs and liquid egg white were mixed with (99m)Tc-sulfur colloid and cooked by either microwaving or frying on a griddle. The cooked eggs were tested for breakdown after 2 and 4 h of incubation in gastric fluid or HCl.

RESULTS

Labeled liquid egg white, prepared by either method of cooking, exhibited less breakdown in gastric fluid than whole eggs. Whole eggs cooked in the microwave exhibited significantly more breakdown than liquid egg white.

CONCLUSION

(99m)Tc-Sulfur colloid binds better to egg whites compared with whole eggs. These results emphasize the need to evaluate the stability of new radiolabeled test meal preparations, including the method of cooking.

Authors+Show Affiliations

Division of Nuclear Medicine, Department of Radiology, Temple University School of Medicine and Hospital, Philadelphia, PA 19140, USA. Lknight@temple.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17942806

Citation

Knight, Linda C., et al. "Egg Labeling Methods for Gastric Emptying Scintigraphy Are Not Equivalent in Producing a Stable Solid Meal." Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, vol. 48, no. 11, 2007, pp. 1897-900.
Knight LC, Kantor S, Doma S, et al. Egg labeling methods for gastric emptying scintigraphy are not equivalent in producing a stable solid meal. J Nucl Med. 2007;48(11):1897-900.
Knight, L. C., Kantor, S., Doma, S., Parkman, H. P., & Maurer, A. H. (2007). Egg labeling methods for gastric emptying scintigraphy are not equivalent in producing a stable solid meal. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 48(11), 1897-900.
Knight LC, et al. Egg Labeling Methods for Gastric Emptying Scintigraphy Are Not Equivalent in Producing a Stable Solid Meal. J Nucl Med. 2007;48(11):1897-900. PubMed PMID: 17942806.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Egg labeling methods for gastric emptying scintigraphy are not equivalent in producing a stable solid meal. AU - Knight,Linda C, AU - Kantor,Steven, AU - Doma,Siva, AU - Parkman,Henry P, AU - Maurer,Alan H, Y1 - 2007/10/17/ PY - 2007/10/19/pubmed PY - 2008/1/31/medline PY - 2007/10/19/entrez SP - 1897 EP - 900 JF - Journal of nuclear medicine : official publication, Society of Nuclear Medicine JO - J Nucl Med VL - 48 IS - 11 N2 - UNLABELLED: A wide range of radiolabeled test meals have been used for gastric emptying scintigraphy. The purpose of this study was to test whether (99m)Tc-sulfur colloid-labeled liquid egg white is as stable as 2 fresh whole eggs labeled with (99m)Tc-sulfur colloid and whether the cooking method is important. METHODS: Whole eggs and liquid egg white were mixed with (99m)Tc-sulfur colloid and cooked by either microwaving or frying on a griddle. The cooked eggs were tested for breakdown after 2 and 4 h of incubation in gastric fluid or HCl. RESULTS: Labeled liquid egg white, prepared by either method of cooking, exhibited less breakdown in gastric fluid than whole eggs. Whole eggs cooked in the microwave exhibited significantly more breakdown than liquid egg white. CONCLUSION: (99m)Tc-Sulfur colloid binds better to egg whites compared with whole eggs. These results emphasize the need to evaluate the stability of new radiolabeled test meal preparations, including the method of cooking. SN - 0161-5505 UR - https://www.unboundmedicine.com/medline/citation/17942806/Egg_labeling_methods_for_gastric_emptying_scintigraphy_are_not_equivalent_in_producing_a_stable_solid_meal_ L2 - http://jnm.snmjournals.org/cgi/pmidlookup?view=long&pmid=17942806 DB - PRIME DP - Unbound Medicine ER -