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Which evolutionary processes influence natural genetic variation for phenotypic traits?
Nat Rev Genet. 2007 Nov; 8(11):845-56.NR

Abstract

Although many studies provide examples of evolutionary processes such as adaptive evolution, balancing selection, deleterious variation and genetic drift, the relative importance of these selective and stochastic processes for phenotypic variation within and among populations is unclear. Theoretical and empirical studies from humans as well as natural animal and plant populations have made progress in examining the role of these evolutionary forces within species. Tentative generalizations about evolutionary processes across species are beginning to emerge, as well as contrasting patterns that characterize different groups of organisms. Furthermore, recent technical advances now allow the combination of ecological measurements of selection in natural environments with population genetic analysis of cloned QTLs, promising advances in identifying the evolutionary processes that influence natural genetic variation.

Authors+Show Affiliations

Mitchell-Olds T
Department of Biology, BOX 90338, Duke University, Durham, North Carolina 27708, USA. tmo1@duke.edu
Willis JH
No affiliation info available
Goldstein DB
No affiliation info available

MeSH

AnimalsEvolution, MolecularGenetic VariationHumansPhenotypeQuantitative Trait Loci

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review

Language

eng

PubMed ID

17943192

Citation

Mitchell-Olds, Thomas, et al. "Which Evolutionary Processes Influence Natural Genetic Variation for Phenotypic Traits?" Nature Reviews. Genetics, vol. 8, no. 11, 2007, pp. 845-56.
Mitchell-Olds T, Willis JH, Goldstein DB. Which evolutionary processes influence natural genetic variation for phenotypic traits? Nat Rev Genet. 2007;8(11):845-56.
Mitchell-Olds, T., Willis, J. H., & Goldstein, D. B. (2007). Which evolutionary processes influence natural genetic variation for phenotypic traits? Nature Reviews. Genetics, 8(11), 845-56.
Mitchell-Olds T, Willis JH, Goldstein DB. Which Evolutionary Processes Influence Natural Genetic Variation for Phenotypic Traits. Nat Rev Genet. 2007;8(11):845-56. PubMed PMID: 17943192.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Which evolutionary processes influence natural genetic variation for phenotypic traits? AU - Mitchell-Olds,Thomas, AU - Willis,John H, AU - Goldstein,David B, PY - 2007/10/19/pubmed PY - 2007/11/7/medline PY - 2007/10/19/entrez SP - 845 EP - 56 JF - Nature reviews. Genetics JO - Nat Rev Genet VL - 8 IS - 11 N2 - Although many studies provide examples of evolutionary processes such as adaptive evolution, balancing selection, deleterious variation and genetic drift, the relative importance of these selective and stochastic processes for phenotypic variation within and among populations is unclear. Theoretical and empirical studies from humans as well as natural animal and plant populations have made progress in examining the role of these evolutionary forces within species. Tentative generalizations about evolutionary processes across species are beginning to emerge, as well as contrasting patterns that characterize different groups of organisms. Furthermore, recent technical advances now allow the combination of ecological measurements of selection in natural environments with population genetic analysis of cloned QTLs, promising advances in identifying the evolutionary processes that influence natural genetic variation. SN - 1471-0064 UR - https://www.unboundmedicine.com/medline/citation/17943192/Which_evolutionary_processes_influence_natural_genetic_variation_for_phenotypic_traits L2 - https://doi.org/10.1038/nrg2207 DB - PRIME DP - Unbound Medicine ER -