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Home-based management of fever and malaria treatment practices in Uganda.
Trans R Soc Trop Med Hyg. 2007 Dec; 101(12):1199-207.TR

Abstract

The Home-Based Management of Fever/Malaria (HBMF) strategy in rural Uganda was evaluated in a quasi-experimental study. The intervention consisted of volunteers educating mothers and providing a 3-day course of pre-packaged chloroquine plus sulfadoxine/pyrimethamine tablets (HOMAPAK), free of charge, for the treatment of under-five fevers. Using a structured questionnaire, information was obtained on care-seeking and treatment practices before (n=498) and 18 months after the introduction of HBMF (n=587). Assessment of the intervention effect indicated 13.5% improvement in the accumulated proportion of patients (1) treated, (2) treated within 24h of illness onset, (3) treated with the recommended antimalarials, (4) treated at an adequate dosage and (5) treated for the correct duration. Combining this with the antimalarial drug efficacy resulted in a 10.4% improvement in the community effectiveness of malaria treatment. HOMAPAK use was reported in 25% of 156 febrile children; 23% in the most poor compared with 50% in the least poor. Using HOMAPAK instead of other allopathic antimalarials increased the likelihood of completing all steps (odds ratio 37, 95% CI 4.8-286). Similar to other large-scale public health interventions, this study demonstrates modest practice changes at the population level. However, practices improved markedly among HOMAPAK users, suggesting that intensifying implementation efforts to increase HOMAPAK use, especially among the poorest, would be beneficial.

Authors+Show Affiliations

Department of Pharmacology and Therapeutics, Makerere University, Kampala, Uganda. jsabiiti@infocom.co.ugNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17945320

Citation

Nsungwa-Sabiiti, Jesca, et al. "Home-based Management of Fever and Malaria Treatment Practices in Uganda." Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 101, no. 12, 2007, pp. 1199-207.
Nsungwa-Sabiiti J, Peterson S, Pariyo G, et al. Home-based management of fever and malaria treatment practices in Uganda. Trans R Soc Trop Med Hyg. 2007;101(12):1199-207.
Nsungwa-Sabiiti, J., Peterson, S., Pariyo, G., Ogwal-Okeng, J., Petzold, M. G., & Tomson, G. (2007). Home-based management of fever and malaria treatment practices in Uganda. Transactions of the Royal Society of Tropical Medicine and Hygiene, 101(12), 1199-207.
Nsungwa-Sabiiti J, et al. Home-based Management of Fever and Malaria Treatment Practices in Uganda. Trans R Soc Trop Med Hyg. 2007;101(12):1199-207. PubMed PMID: 17945320.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Home-based management of fever and malaria treatment practices in Uganda. AU - Nsungwa-Sabiiti,Jesca, AU - Peterson,Stefan, AU - Pariyo,George, AU - Ogwal-Okeng,Jasper, AU - Petzold,Max G, AU - Tomson,Goran, Y1 - 2007/10/22/ PY - 2007/02/05/received PY - 2007/08/13/revised PY - 2007/08/14/accepted PY - 2007/10/20/pubmed PY - 2008/5/3/medline PY - 2007/10/20/entrez SP - 1199 EP - 207 JF - Transactions of the Royal Society of Tropical Medicine and Hygiene JO - Trans R Soc Trop Med Hyg VL - 101 IS - 12 N2 - The Home-Based Management of Fever/Malaria (HBMF) strategy in rural Uganda was evaluated in a quasi-experimental study. The intervention consisted of volunteers educating mothers and providing a 3-day course of pre-packaged chloroquine plus sulfadoxine/pyrimethamine tablets (HOMAPAK), free of charge, for the treatment of under-five fevers. Using a structured questionnaire, information was obtained on care-seeking and treatment practices before (n=498) and 18 months after the introduction of HBMF (n=587). Assessment of the intervention effect indicated 13.5% improvement in the accumulated proportion of patients (1) treated, (2) treated within 24h of illness onset, (3) treated with the recommended antimalarials, (4) treated at an adequate dosage and (5) treated for the correct duration. Combining this with the antimalarial drug efficacy resulted in a 10.4% improvement in the community effectiveness of malaria treatment. HOMAPAK use was reported in 25% of 156 febrile children; 23% in the most poor compared with 50% in the least poor. Using HOMAPAK instead of other allopathic antimalarials increased the likelihood of completing all steps (odds ratio 37, 95% CI 4.8-286). Similar to other large-scale public health interventions, this study demonstrates modest practice changes at the population level. However, practices improved markedly among HOMAPAK users, suggesting that intensifying implementation efforts to increase HOMAPAK use, especially among the poorest, would be beneficial. SN - 0035-9203 UR - https://www.unboundmedicine.com/medline/citation/17945320/Home_based_management_of_fever_and_malaria_treatment_practices_in_Uganda_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0035-9203(07)00246-5 DB - PRIME DP - Unbound Medicine ER -