Tags

Type your tag names separated by a space and hit enter

Contrast-enhanced multi-shot echo-planar FLAIR in the depiction of metastatic tumors of the brain: comparison with contrast-enhanced spin-echo T1-weighted imaging.
Acta Radiol. 2007 Nov; 48(9):1032-7.AR

Abstract

BACKGROUND

The usefulness of fast fluid-attenuated inversion-recovery (FLAIR) sequences after administration of contrast medium (f-FLAIR (+)) has been shown in depicting brain tumors including metastases and meningeal carcinomatosis. Contrast-enhanced multi-shot echo-planar FLAIR (Ms-EPI-FLAIR (+)), comprising combined sequences of f-FLAIR (+) and Ms-EPI, may provide the advantages of f-FLAIR (+) along with rapid acquisition.

PURPOSE

To compare Ms-EPI-FLAIR (+) with post-contrast spin-echo T1-weighted imaging (SE-T1WI (+)) in the depiction of brain metastases.

MATERIAL AND METHODS

In 14 patients with metastatic tumors of the brain, spin-echo precontrast T1-weighted imaging (SE-T1WI (-)), fast spin-echo T2-weighted imaging (FSE-T2WI), fast-FLAIR, SE-T1WI (+), and Ms-EPI-FLAIR (+) were acquired. For qualitative evaluation of SE-T1WI (+) and Ms-EPI-FLAIR (+), receiver operating characteristic (ROC) analysis was performed in two different readers. For quantitative analysis, the intensity ratios (intensity of tumor divided by intensity of peritumoral region) in SE-T1WI (+) and Ms-EPI-FLAIR (+) were compared.

RESULTS

Although pre-contrast f-FLAIR detected 84 of 106 tumors, Ms-EPI-FLAIR (+) detected 98 of 106 tumors. In the ROC analysis for observers A and B, Az values in SE-T1WI (+) did not differ from values in Ms-EPI-FLAIR (+). Quantitatively, the intensity ratio in Ms-EPI-FLAIR (+) also did not differ from that in SE-T1WI (+).

CONCLUSION

Detectability of brain metastases with Ms-EPI-FLAIR (+) is almost similar to that with SE-T1WI (+). Ms-EPI-FLAIR (+) could be an alternative to SE-T1WI (+) in the depiction of brain metastases.

Authors+Show Affiliations

Department of Radiology, Akita University School of Medicine, Akita, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

17957522

Citation

Tomura, N, et al. "Contrast-enhanced Multi-shot Echo-planar FLAIR in the Depiction of Metastatic Tumors of the Brain: Comparison With Contrast-enhanced Spin-echo T1-weighted Imaging." Acta Radiologica (Stockholm, Sweden : 1987), vol. 48, no. 9, 2007, pp. 1032-7.
Tomura N, Narita K, Takahashi S, et al. Contrast-enhanced multi-shot echo-planar FLAIR in the depiction of metastatic tumors of the brain: comparison with contrast-enhanced spin-echo T1-weighted imaging. Acta Radiol. 2007;48(9):1032-7.
Tomura, N., Narita, K., Takahashi, S., Otani, T., Sakuma, I., Yasuda, K., Nishii, T., & Watarai, J. (2007). Contrast-enhanced multi-shot echo-planar FLAIR in the depiction of metastatic tumors of the brain: comparison with contrast-enhanced spin-echo T1-weighted imaging. Acta Radiologica (Stockholm, Sweden : 1987), 48(9), 1032-7.
Tomura N, et al. Contrast-enhanced Multi-shot Echo-planar FLAIR in the Depiction of Metastatic Tumors of the Brain: Comparison With Contrast-enhanced Spin-echo T1-weighted Imaging. Acta Radiol. 2007;48(9):1032-7. PubMed PMID: 17957522.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Contrast-enhanced multi-shot echo-planar FLAIR in the depiction of metastatic tumors of the brain: comparison with contrast-enhanced spin-echo T1-weighted imaging. AU - Tomura,N, AU - Narita,K, AU - Takahashi,S, AU - Otani,T, AU - Sakuma,I, AU - Yasuda,K, AU - Nishii,T, AU - Watarai,J, PY - 2007/10/25/pubmed PY - 2007/12/14/medline PY - 2007/10/25/entrez SP - 1032 EP - 7 JF - Acta radiologica (Stockholm, Sweden : 1987) JO - Acta Radiol VL - 48 IS - 9 N2 - BACKGROUND: The usefulness of fast fluid-attenuated inversion-recovery (FLAIR) sequences after administration of contrast medium (f-FLAIR (+)) has been shown in depicting brain tumors including metastases and meningeal carcinomatosis. Contrast-enhanced multi-shot echo-planar FLAIR (Ms-EPI-FLAIR (+)), comprising combined sequences of f-FLAIR (+) and Ms-EPI, may provide the advantages of f-FLAIR (+) along with rapid acquisition. PURPOSE: To compare Ms-EPI-FLAIR (+) with post-contrast spin-echo T1-weighted imaging (SE-T1WI (+)) in the depiction of brain metastases. MATERIAL AND METHODS: In 14 patients with metastatic tumors of the brain, spin-echo precontrast T1-weighted imaging (SE-T1WI (-)), fast spin-echo T2-weighted imaging (FSE-T2WI), fast-FLAIR, SE-T1WI (+), and Ms-EPI-FLAIR (+) were acquired. For qualitative evaluation of SE-T1WI (+) and Ms-EPI-FLAIR (+), receiver operating characteristic (ROC) analysis was performed in two different readers. For quantitative analysis, the intensity ratios (intensity of tumor divided by intensity of peritumoral region) in SE-T1WI (+) and Ms-EPI-FLAIR (+) were compared. RESULTS: Although pre-contrast f-FLAIR detected 84 of 106 tumors, Ms-EPI-FLAIR (+) detected 98 of 106 tumors. In the ROC analysis for observers A and B, Az values in SE-T1WI (+) did not differ from values in Ms-EPI-FLAIR (+). Quantitatively, the intensity ratio in Ms-EPI-FLAIR (+) also did not differ from that in SE-T1WI (+). CONCLUSION: Detectability of brain metastases with Ms-EPI-FLAIR (+) is almost similar to that with SE-T1WI (+). Ms-EPI-FLAIR (+) could be an alternative to SE-T1WI (+) in the depiction of brain metastases. SN - 1600-0455 UR - https://www.unboundmedicine.com/medline/citation/17957522/Contrast_enhanced_multi_shot_echo_planar_FLAIR_in_the_depiction_of_metastatic_tumors_of_the_brain:_comparison_with_contrast_enhanced_spin_echo_T1_weighted_imaging_ L2 - https://journals.sagepub.com/doi/10.1080/02841850701499425?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -