Tags

Type your tag names separated by a space and hit enter

Prevalence of glaucoma in a South brazilian population: Projeto Glaucoma.
Invest Ophthalmol Vis Sci 2007; 48(11):4974-9IO

Abstract

PURPOSE

To assess the prevalence of glaucoma in a South Brazilian population.

METHODS

Subjects older than 40 years underwent a screening examination that included a medical interview, slit lamp examination, tonometry, and fundoscopy. Those with suspected glaucoma (based on optic disc appearance and/or intraocular pressure) underwent a comprehensive ophthalmic evaluation during the definitive examination. Glaucoma was diagnosed based on the International Society of Geographical and Epidemiologic Ophthalmology classification.

RESULTS

A total of 1636 subjects were examined (76.5% participation rate); 71% of the study population self-reported their race as white and 24% as nonwhite (most black and mixed-black/white). Glaucoma was found in 56 subjects (crude prevalence of all glaucoma: 3.4%; 95% CI, 2.5-4.3), primary open-angle glaucoma (POAG) was found in 40 (2.4%; 95% CI, 1.7-3.2), and primary angle-closure glaucoma (PACG) in 12 (0.7%; 95% CI, 0.3-1.1). Six (12%) subjects with primary glaucoma had a previous diagnosis of the disease. Nonwhite persons had a higher prevalence rate of POAG than did white participants, although this difference was not significant (3.8% vs. 2.1%, respectively, P = 0.11). Unilateral blindness due to primary glaucoma was observed in seven subjects (five POAG/2 PACG), and nonwhites had a higher rate of unilateral blindness than did whites (five versus two cases, respectively, P = 0.014).

CONCLUSIONS

Compared to incidence in Hispanic and European populations, PACG was more common among South Brazilians, whereas the POAG rates were similar. The rate of undiagnosed glaucoma was almost 90%. The higher POAG prevalence in the population self-reported as nonwhite may affect the estimation of glaucoma in Brazil, as more than 40% of the population self-report their race as nonwhite.

Authors+Show Affiliations

Department of Ophthalmology, Universidade Federal do Paraná, Curitiba, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17962447

Citation

Sakata, Kenji, et al. "Prevalence of Glaucoma in a South Brazilian Population: Projeto Glaucoma." Investigative Ophthalmology & Visual Science, vol. 48, no. 11, 2007, pp. 4974-9.
Sakata K, Sakata LM, Sakata VM, et al. Prevalence of glaucoma in a South brazilian population: Projeto Glaucoma. Invest Ophthalmol Vis Sci. 2007;48(11):4974-9.
Sakata, K., Sakata, L. M., Sakata, V. M., Santini, C., Hopker, L. M., Bernardes, R., ... Moreira, A. T. (2007). Prevalence of glaucoma in a South brazilian population: Projeto Glaucoma. Investigative Ophthalmology & Visual Science, 48(11), pp. 4974-9.
Sakata K, et al. Prevalence of Glaucoma in a South Brazilian Population: Projeto Glaucoma. Invest Ophthalmol Vis Sci. 2007;48(11):4974-9. PubMed PMID: 17962447.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of glaucoma in a South brazilian population: Projeto Glaucoma. AU - Sakata,Kenji, AU - Sakata,Lisandro M, AU - Sakata,Viviane M, AU - Santini,Cintia, AU - Hopker,Luisa M, AU - Bernardes,Ricardo, AU - Yabumoto,Cristina, AU - Moreira,Ana T R, PY - 2007/10/27/pubmed PY - 2007/12/7/medline PY - 2007/10/27/entrez SP - 4974 EP - 9 JF - Investigative ophthalmology & visual science JO - Invest. Ophthalmol. Vis. Sci. VL - 48 IS - 11 N2 - PURPOSE: To assess the prevalence of glaucoma in a South Brazilian population. METHODS: Subjects older than 40 years underwent a screening examination that included a medical interview, slit lamp examination, tonometry, and fundoscopy. Those with suspected glaucoma (based on optic disc appearance and/or intraocular pressure) underwent a comprehensive ophthalmic evaluation during the definitive examination. Glaucoma was diagnosed based on the International Society of Geographical and Epidemiologic Ophthalmology classification. RESULTS: A total of 1636 subjects were examined (76.5% participation rate); 71% of the study population self-reported their race as white and 24% as nonwhite (most black and mixed-black/white). Glaucoma was found in 56 subjects (crude prevalence of all glaucoma: 3.4%; 95% CI, 2.5-4.3), primary open-angle glaucoma (POAG) was found in 40 (2.4%; 95% CI, 1.7-3.2), and primary angle-closure glaucoma (PACG) in 12 (0.7%; 95% CI, 0.3-1.1). Six (12%) subjects with primary glaucoma had a previous diagnosis of the disease. Nonwhite persons had a higher prevalence rate of POAG than did white participants, although this difference was not significant (3.8% vs. 2.1%, respectively, P = 0.11). Unilateral blindness due to primary glaucoma was observed in seven subjects (five POAG/2 PACG), and nonwhites had a higher rate of unilateral blindness than did whites (five versus two cases, respectively, P = 0.014). CONCLUSIONS: Compared to incidence in Hispanic and European populations, PACG was more common among South Brazilians, whereas the POAG rates were similar. The rate of undiagnosed glaucoma was almost 90%. The higher POAG prevalence in the population self-reported as nonwhite may affect the estimation of glaucoma in Brazil, as more than 40% of the population self-report their race as nonwhite. SN - 0146-0404 UR - https://www.unboundmedicine.com/medline/citation/17962447/Prevalence_of_glaucoma_in_a_South_brazilian_population:_Projeto_Glaucoma_ L2 - http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.07-0342 DB - PRIME DP - Unbound Medicine ER -