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Clinical outcomes in children with hyoscyamus niger intoxication not receiving physostigmine therapy.
Eur J Emerg Med 2007; 14(6):348-50EJ

Abstract

OBJECTIVE

Diagnosis of hyoscyamus niger intoxication is based on clinical symptomatology and history. Therapy includes stomach lavage, supportive therapy, and physostigmine as a specific antidote. Physostigmine is not available in Turkey. This retrospective study investigated the clinical outcomes in children with hyoscyamus niger intoxication who did not receive physostigmine therapy.

METHODS

Twenty-three children whose history and medical records indicated hyoscyamus niger intoxication were included the study.

RESULTS

None of the cases had any abnormal laboratory findings. All the patients were performed gastric lavage and provided with supportive therapy. None of the children had any complications, and none required mechanical ventilation or died. All the patients were discharged in good health within 48 h.

CONCLUSION

Our findings suggest that hyoscyamus niger intoxication in children is self-terminating and responds to supportive therapy and that routine use of physostigmine is unnecessary in every case with hyoscyamus niger intoxication.

Authors+Show Affiliations

Department of Pediatrics, Ataturk University, Faculty of Medicine, Erzurum, Turkey. hdoneray@hotmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17968201

Citation

Doneray, Hakan, et al. "Clinical Outcomes in Children With Hyoscyamus Niger Intoxication Not Receiving Physostigmine Therapy." European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine, vol. 14, no. 6, 2007, pp. 348-50.
Doneray H, Orbak Z, Karakelleoglu C. Clinical outcomes in children with hyoscyamus niger intoxication not receiving physostigmine therapy. Eur J Emerg Med. 2007;14(6):348-50.
Doneray, H., Orbak, Z., & Karakelleoglu, C. (2007). Clinical outcomes in children with hyoscyamus niger intoxication not receiving physostigmine therapy. European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine, 14(6), pp. 348-50.
Doneray H, Orbak Z, Karakelleoglu C. Clinical Outcomes in Children With Hyoscyamus Niger Intoxication Not Receiving Physostigmine Therapy. Eur J Emerg Med. 2007;14(6):348-50. PubMed PMID: 17968201.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical outcomes in children with hyoscyamus niger intoxication not receiving physostigmine therapy. AU - Doneray,Hakan, AU - Orbak,Zerrin, AU - Karakelleoglu,Cahit, PY - 2007/10/31/pubmed PY - 2008/2/21/medline PY - 2007/10/31/entrez SP - 348 EP - 50 JF - European journal of emergency medicine : official journal of the European Society for Emergency Medicine JO - Eur J Emerg Med VL - 14 IS - 6 N2 - OBJECTIVE: Diagnosis of hyoscyamus niger intoxication is based on clinical symptomatology and history. Therapy includes stomach lavage, supportive therapy, and physostigmine as a specific antidote. Physostigmine is not available in Turkey. This retrospective study investigated the clinical outcomes in children with hyoscyamus niger intoxication who did not receive physostigmine therapy. METHODS: Twenty-three children whose history and medical records indicated hyoscyamus niger intoxication were included the study. RESULTS: None of the cases had any abnormal laboratory findings. All the patients were performed gastric lavage and provided with supportive therapy. None of the children had any complications, and none required mechanical ventilation or died. All the patients were discharged in good health within 48 h. CONCLUSION: Our findings suggest that hyoscyamus niger intoxication in children is self-terminating and responds to supportive therapy and that routine use of physostigmine is unnecessary in every case with hyoscyamus niger intoxication. SN - 0969-9546 UR - https://www.unboundmedicine.com/medline/citation/17968201/Clinical_outcomes_in_children_with_hyoscyamus_niger_intoxication_not_receiving_physostigmine_therapy L2 - http://dx.doi.org/10.1097/MEJ.0b013e328122de2f DB - PRIME DP - Unbound Medicine ER -