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Nutritional status and depression, sleep disorder, and quality of life in hemodialysis patients.

Abstract

OBJECTIVE

The malnutrition-inflammation score (MIS) is a scoring system that measures malnutrition and inflammation. We sought to explore its associations with depression, sleep disturbance, and quality of life.

DESIGN

This was a cross-sectional study.

SETTING

This study took place at the Baskent University Outpatient Hemodialysis Unit (Ankara, Turkey).

PATIENTS

We enrolled 67 hemodialysis patients (male/female, 34/33; age, 47.7 +/- 11.4 years [mean +/- SD]; hemodialysis duration, 103.7 +/- 59.1 months [mean +/- SD]).

INTERVENTION

We retrospectively recorded patients' monthly clinical and laboratory findings from the previous 6 months. The same physician calculated MIS scores. We interviewed all patients, and each completed a Beck Depression Inventory (BDI) assessment. We used the Pittsburgh Sleep Quality Index (PSQI) to assess quality of sleep, and the Medical Outcomes Study 36-item short form (SF-36) questionnaire to evaluate health-related quality of life.

MAIN OUTCOME MEASURES

The main outcome measures involved the univariate and multivariate relationships of the MIS with BDI, PSQI, and SF-36.

RESULTS

Patients with PSQI scores of < or = 5 ("good sleepers") had lower MIS scores than did poor sleepers (6.8 +/- 2.5 vs. 8.8 +/- 3.2, P < .05). Patients with moderate-to-severe depression (BDI score > or = 19) had higher MIS scores (9.0 +/- 3.2 vs. 6.5 +/- 2.5, P = .005) and higher PSQI scores (7.6 +/- 2.1 vs. 4.7 +/- 1.8, P = .001), compared with patients with BDI scores < 19. Increased MIS scores were correlated with increased comorbidity (P = .01) and poor SF-36 scores (P = .009).

CONCLUSION

Increased MIS is significantly associated with the presence of depression, sleep disorders, and poor quality of life. This close relationship may help establish the MIS as an important determinant of the increased morbidity and mortality of hemodialysis patients.

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  • Authors+Show Affiliations

    ,

    Department of Nephrology, Baskent University Faculty of Medicine, Ankara, Turkey. aysebati@gmail.com

    , , , ,

    Source

    MeSH

    Comorbidity
    Cross-Sectional Studies
    Depression
    Female
    Humans
    Inflammation
    Kidney Failure, Chronic
    Male
    Middle Aged
    Multivariate Analysis
    Nutritional Status
    Protein-Energy Malnutrition
    Quality of Life
    Renal Dialysis
    Retrospective Studies
    Sleep Wake Disorders
    Surveys and Questionnaires

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    17971310

    Citation

    Bilgic, Ayse, et al. "Nutritional Status and Depression, Sleep Disorder, and Quality of Life in Hemodialysis Patients." Journal of Renal Nutrition : the Official Journal of the Council On Renal Nutrition of the National Kidney Foundation, vol. 17, no. 6, 2007, pp. 381-8.
    Bilgic A, Akgul A, Sezer S, et al. Nutritional status and depression, sleep disorder, and quality of life in hemodialysis patients. J Ren Nutr. 2007;17(6):381-8.
    Bilgic, A., Akgul, A., Sezer, S., Arat, Z., Ozdemir, F. N., & Haberal, M. (2007). Nutritional status and depression, sleep disorder, and quality of life in hemodialysis patients. Journal of Renal Nutrition : the Official Journal of the Council On Renal Nutrition of the National Kidney Foundation, 17(6), pp. 381-8.
    Bilgic A, et al. Nutritional Status and Depression, Sleep Disorder, and Quality of Life in Hemodialysis Patients. J Ren Nutr. 2007;17(6):381-8. PubMed PMID: 17971310.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Nutritional status and depression, sleep disorder, and quality of life in hemodialysis patients. AU - Bilgic,Ayse, AU - Akgul,Arzu, AU - Sezer,Siren, AU - Arat,Zubeyde, AU - Ozdemir,F Nurhan, AU - Haberal,Mehmet, PY - 2007/05/13/received PY - 2007/11/1/pubmed PY - 2007/12/6/medline PY - 2007/11/1/entrez SP - 381 EP - 8 JF - Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation JO - J Ren Nutr VL - 17 IS - 6 N2 - OBJECTIVE: The malnutrition-inflammation score (MIS) is a scoring system that measures malnutrition and inflammation. We sought to explore its associations with depression, sleep disturbance, and quality of life. DESIGN: This was a cross-sectional study. SETTING: This study took place at the Baskent University Outpatient Hemodialysis Unit (Ankara, Turkey). PATIENTS: We enrolled 67 hemodialysis patients (male/female, 34/33; age, 47.7 +/- 11.4 years [mean +/- SD]; hemodialysis duration, 103.7 +/- 59.1 months [mean +/- SD]). INTERVENTION: We retrospectively recorded patients' monthly clinical and laboratory findings from the previous 6 months. The same physician calculated MIS scores. We interviewed all patients, and each completed a Beck Depression Inventory (BDI) assessment. We used the Pittsburgh Sleep Quality Index (PSQI) to assess quality of sleep, and the Medical Outcomes Study 36-item short form (SF-36) questionnaire to evaluate health-related quality of life. MAIN OUTCOME MEASURES: The main outcome measures involved the univariate and multivariate relationships of the MIS with BDI, PSQI, and SF-36. RESULTS: Patients with PSQI scores of < or = 5 ("good sleepers") had lower MIS scores than did poor sleepers (6.8 +/- 2.5 vs. 8.8 +/- 3.2, P < .05). Patients with moderate-to-severe depression (BDI score > or = 19) had higher MIS scores (9.0 +/- 3.2 vs. 6.5 +/- 2.5, P = .005) and higher PSQI scores (7.6 +/- 2.1 vs. 4.7 +/- 1.8, P = .001), compared with patients with BDI scores < 19. Increased MIS scores were correlated with increased comorbidity (P = .01) and poor SF-36 scores (P = .009). CONCLUSION: Increased MIS is significantly associated with the presence of depression, sleep disorders, and poor quality of life. This close relationship may help establish the MIS as an important determinant of the increased morbidity and mortality of hemodialysis patients. SN - 1532-8503 UR - https://www.unboundmedicine.com/medline/citation/17971310/Nutritional_status_and_depression_sleep_disorder_and_quality_of_life_in_hemodialysis_patients_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1051-2276(07)00178-1 DB - PRIME DP - Unbound Medicine ER -