[Acute fatty liver in pregnancy].Srp Arh Celok Lek. 1994 Jul-Aug; 122(7-8):239-41.SA
Acute fatty liver in pregnancy (AFLP) is a rare disease with sudden onset in the third trimester of pregnancy characterized by jaundice, bleeding, liver failure and encephalopathy. The cause of AFLP is unknown. It is of short duration and high risk of mortality. The aim of this paper is to describe a patient who was hospitalised in the 36th week of pregnancy due to jaundice and bleeding. Upon arrival the patient delivered a dead infant, and thereafter jaundice, severe bleeding and encephalopathy deteriorated. The patient's laboratory results revealed AFLP which was confirmed with increased echogenicity of the liver. Spontaneous delivery and maximal supportive therapy contributed to successful recovery of the patient in spite of severe haemorrhage, encephalopathy, acute ranal failure, polyserositis and adult respiratory distress syndrome.