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Development and evaluation of new blood pressure and heart rate signal analysis techniques to assess orthostatic hypotension and its subtypes.
Physiol Meas. 2007 Nov; 28(11):N87-102.PM

Abstract

Orthostatic hypotension (OH) is a clinical condition, which frequently results in symptoms such as syncope, dizziness during standing, weakness, blurred vision and fatigue. It is defined as a sustained drop in blood pressure exceeding 20 mmHg systolic or 10 mmHg diastolic occurring within 3 min of assuming upright posture, and is a common causal factor for falls in the elderly. Since 1986, tilt-table testing has become widely used in the diagnosis of OH. The Finometer provides non-invasive monitoring of haemodynamic changes during tilt-table testing. In this study, new algorithms for parameter extraction from Finometer data were developed, with specific reference to the diagnosis of OH. Algorithms were developed to assess the rates of change of haemodynamic variables in response to head-up tilt testing, a previously unexamined aspect of tilt-table testing. These algorithms were applied to the Finometer measurements of 20 patients, who underwent tilt-table testing in the Mid-Western Regional Hospital, Limerick. The data extraction algorithms were shown to accurately record changes in haemodynamic variables for further analysis. It was also demonstrated that the rate of change of blood pressure during the head-up tilt-table testing could have prognostic significance for OH.

Authors+Show Affiliations

Department of Electronic Engineering, National University of Ireland, Galway, Ireland. briandeegan@oceanfree.netNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17978417

Citation

Deegan, B M T., et al. "Development and Evaluation of New Blood Pressure and Heart Rate Signal Analysis Techniques to Assess Orthostatic Hypotension and Its Subtypes." Physiological Measurement, vol. 28, no. 11, 2007, pp. N87-102.
Deegan BM, O'Connor M, Lyons D, et al. Development and evaluation of new blood pressure and heart rate signal analysis techniques to assess orthostatic hypotension and its subtypes. Physiol Meas. 2007;28(11):N87-102.
Deegan, B. M., O'Connor, M., Lyons, D., & OLaighin, G. (2007). Development and evaluation of new blood pressure and heart rate signal analysis techniques to assess orthostatic hypotension and its subtypes. Physiological Measurement, 28(11), N87-102.
Deegan BM, et al. Development and Evaluation of New Blood Pressure and Heart Rate Signal Analysis Techniques to Assess Orthostatic Hypotension and Its Subtypes. Physiol Meas. 2007;28(11):N87-102. PubMed PMID: 17978417.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Development and evaluation of new blood pressure and heart rate signal analysis techniques to assess orthostatic hypotension and its subtypes. AU - Deegan,B M T, AU - O'Connor,M, AU - Lyons,D, AU - OLaighin,G, Y1 - 2007/10/05/ PY - 2007/11/6/pubmed PY - 2008/1/19/medline PY - 2007/11/6/entrez SP - N87 EP - 102 JF - Physiological measurement JO - Physiol Meas VL - 28 IS - 11 N2 - Orthostatic hypotension (OH) is a clinical condition, which frequently results in symptoms such as syncope, dizziness during standing, weakness, blurred vision and fatigue. It is defined as a sustained drop in blood pressure exceeding 20 mmHg systolic or 10 mmHg diastolic occurring within 3 min of assuming upright posture, and is a common causal factor for falls in the elderly. Since 1986, tilt-table testing has become widely used in the diagnosis of OH. The Finometer provides non-invasive monitoring of haemodynamic changes during tilt-table testing. In this study, new algorithms for parameter extraction from Finometer data were developed, with specific reference to the diagnosis of OH. Algorithms were developed to assess the rates of change of haemodynamic variables in response to head-up tilt testing, a previously unexamined aspect of tilt-table testing. These algorithms were applied to the Finometer measurements of 20 patients, who underwent tilt-table testing in the Mid-Western Regional Hospital, Limerick. The data extraction algorithms were shown to accurately record changes in haemodynamic variables for further analysis. It was also demonstrated that the rate of change of blood pressure during the head-up tilt-table testing could have prognostic significance for OH. SN - 0967-3334 UR - https://www.unboundmedicine.com/medline/citation/17978417/Development_and_evaluation_of_new_blood_pressure_and_heart_rate_signal_analysis_techniques_to_assess_orthostatic_hypotension_and_its_subtypes_ L2 - https://doi.org/10.1088/0967-3334/28/11/N01 DB - PRIME DP - Unbound Medicine ER -