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[Anti-gliadin antibodies in the diagnosis and follow-up of celiac disease].
Minerva Pediatr 1991; 43(12):783-8MP

Abstract

The study assessed the value of anti-gliadin antibodies (AGA) as a diagnostic test for celiac disease (CD) by examining 219 children: 57 were affected by malabsorption syndrome and underwent the first duodenojejunal biopsy; 83 underwent a secondary diagnostic phase for CD; 44 underwent a challenge test; 35 controls. Duodenojejunal biopsy was performed in all subjects in the three stages of diagnosis for CD. By comparing AGA levels and on the basis of histological tests of duodenojejunal mucosa it is possible to confirm the reliability of the method as a screening test for use in subjects whose clinical symptoms suggest CD. AGA are however less reliable in the second and third stages, that is to say in the follow-up of CD, since they do not always reflect the conditions of intestinal mucosa.

Authors+Show Affiliations

II Clinica Pediatrica G. Gaslin, Università degli Studi di Genova.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

ita

PubMed ID

1798403

Citation

Sbolgi, P, et al. "[Anti-gliadin Antibodies in the Diagnosis and Follow-up of Celiac Disease]." Minerva Pediatrica, vol. 43, no. 12, 1991, pp. 783-8.
Sbolgi P, Mangiante G, Ruffa G, et al. [Anti-gliadin antibodies in the diagnosis and follow-up of celiac disease]. Minerva Pediatr. 1991;43(12):783-8.
Sbolgi, P., Mangiante, G., Ruffa, G., Caprioli, F., Bartolozzi, G., Cingolani, M., & Gemme, G. (1991). [Anti-gliadin antibodies in the diagnosis and follow-up of celiac disease]. Minerva Pediatrica, 43(12), pp. 783-8.
Sbolgi P, et al. [Anti-gliadin Antibodies in the Diagnosis and Follow-up of Celiac Disease]. Minerva Pediatr. 1991;43(12):783-8. PubMed PMID: 1798403.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Anti-gliadin antibodies in the diagnosis and follow-up of celiac disease]. AU - Sbolgi,P, AU - Mangiante,G, AU - Ruffa,G, AU - Caprioli,F, AU - Bartolozzi,G, AU - Cingolani,M, AU - Gemme,G, PY - 1991/12/1/pubmed PY - 1991/12/1/medline PY - 1991/12/1/entrez SP - 783 EP - 8 JF - Minerva pediatrica JO - Minerva Pediatr. VL - 43 IS - 12 N2 - The study assessed the value of anti-gliadin antibodies (AGA) as a diagnostic test for celiac disease (CD) by examining 219 children: 57 were affected by malabsorption syndrome and underwent the first duodenojejunal biopsy; 83 underwent a secondary diagnostic phase for CD; 44 underwent a challenge test; 35 controls. Duodenojejunal biopsy was performed in all subjects in the three stages of diagnosis for CD. By comparing AGA levels and on the basis of histological tests of duodenojejunal mucosa it is possible to confirm the reliability of the method as a screening test for use in subjects whose clinical symptoms suggest CD. AGA are however less reliable in the second and third stages, that is to say in the follow-up of CD, since they do not always reflect the conditions of intestinal mucosa. SN - 0026-4946 UR - https://www.unboundmedicine.com/medline/citation/1798403/[Anti_gliadin_antibodies_in_the_diagnosis_and_follow_up_of_celiac_disease]_ L2 - http://www.diseaseinfosearch.org/result/1186 DB - PRIME DP - Unbound Medicine ER -