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Diagnosis and differential diagnosis of hypergastrinemia.
Wien Klin Wochenschr. 2007; 119(19-20):564-9.WK

Abstract

The most frequent conditions of hypergastrinemia in man are the Zollinger-Ellison syndrome with autonomous gastrin hypersecretion by the tumour cell and reactive hypergastrinemia in type A autoimmune chronic atrophic gastritis with achlorhydria causing unrestrained gastrin release from the gastrin-producing antral G-cells. Both entities differ with respect to the pH in the gastric fluid, which is < 2 in patients with Zollinger-Ellison syndrome and neutral in type A gastritis. Other conditions with moderate hypergastrinemia as treatment with proton pump inhibitors, gastric outlet obstruction, previous vagotomy, chronic renal failure or short bowel syndrome are of minor clinical importance.

Authors+Show Affiliations

Klinik für Innere Medizin, Schwerpunkt Gastroenterologie und Endokrinologie, Klinikum Giessen-Marburg, Standort Marburg, Philipps Universität, Marburg, Germany. arnoldr@mailer.uni-marburg.de

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

17985088

Citation

Arnold, Rudolf. "Diagnosis and Differential Diagnosis of Hypergastrinemia." Wiener Klinische Wochenschrift, vol. 119, no. 19-20, 2007, pp. 564-9.
Arnold R. Diagnosis and differential diagnosis of hypergastrinemia. Wien Klin Wochenschr. 2007;119(19-20):564-9.
Arnold, R. (2007). Diagnosis and differential diagnosis of hypergastrinemia. Wiener Klinische Wochenschrift, 119(19-20), 564-9.
Arnold R. Diagnosis and Differential Diagnosis of Hypergastrinemia. Wien Klin Wochenschr. 2007;119(19-20):564-9. PubMed PMID: 17985088.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnosis and differential diagnosis of hypergastrinemia. A1 - Arnold,Rudolf, PY - 2007/11/7/pubmed PY - 2008/3/5/medline PY - 2007/11/7/entrez SP - 564 EP - 9 JF - Wiener klinische Wochenschrift JO - Wien Klin Wochenschr VL - 119 IS - 19-20 N2 - The most frequent conditions of hypergastrinemia in man are the Zollinger-Ellison syndrome with autonomous gastrin hypersecretion by the tumour cell and reactive hypergastrinemia in type A autoimmune chronic atrophic gastritis with achlorhydria causing unrestrained gastrin release from the gastrin-producing antral G-cells. Both entities differ with respect to the pH in the gastric fluid, which is < 2 in patients with Zollinger-Ellison syndrome and neutral in type A gastritis. Other conditions with moderate hypergastrinemia as treatment with proton pump inhibitors, gastric outlet obstruction, previous vagotomy, chronic renal failure or short bowel syndrome are of minor clinical importance. SN - 0043-5325 UR - https://www.unboundmedicine.com/medline/citation/17985088/Diagnosis_and_differential_diagnosis_of_hypergastrinemia_ L2 - https://dx.doi.org/10.1007/s00508-007-0878-0 DB - PRIME DP - Unbound Medicine ER -