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Surgical aspects of gastrinoma in multiple endocrine neoplasia type 1.
Wien Klin Wochenschr. 2007; 119(19-20):602-8.WK

Abstract

Gastrinoma is the most frequent functional pancreaticoduodenal endocrine tumor in patients with multiple endocrine neoplasia type 1 (MEN1) and one major determinant of mortality in this syndrome. Whether routine surgical exploration should be performed in a patient with MEN1 associated Zollinger-Ellison syndrome (ZES) to possibly reduce the malignant spread and eventually increase survival still remains controversial. There is not only disagreement about the indication for surgical exploration, but also what type of procedure should be performed, since sufficient evidence-based data are not available. The article discusses the available data on treatment strategies of MEN1 associated ZES.

Authors+Show Affiliations

Klinik für Allgemein- und Viszeralchirurgie der Städt. Kliniken Bielefeld-Mitte, Bielefeld, Germany. bartsch.detlef@sk-bielefeld.deNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

17985096

Citation

Bartsch, Detlef K., et al. "Surgical Aspects of Gastrinoma in Multiple Endocrine Neoplasia Type 1." Wiener Klinische Wochenschrift, vol. 119, no. 19-20, 2007, pp. 602-8.
Bartsch DK, Langer P, Rothmund M. Surgical aspects of gastrinoma in multiple endocrine neoplasia type 1. Wien Klin Wochenschr. 2007;119(19-20):602-8.
Bartsch, D. K., Langer, P., & Rothmund, M. (2007). Surgical aspects of gastrinoma in multiple endocrine neoplasia type 1. Wiener Klinische Wochenschrift, 119(19-20), 602-8.
Bartsch DK, Langer P, Rothmund M. Surgical Aspects of Gastrinoma in Multiple Endocrine Neoplasia Type 1. Wien Klin Wochenschr. 2007;119(19-20):602-8. PubMed PMID: 17985096.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Surgical aspects of gastrinoma in multiple endocrine neoplasia type 1. AU - Bartsch,Detlef K, AU - Langer,Peter, AU - Rothmund,Matthias, PY - 2007/11/7/pubmed PY - 2008/3/5/medline PY - 2007/11/7/entrez SP - 602 EP - 8 JF - Wiener klinische Wochenschrift JO - Wien. Klin. Wochenschr. VL - 119 IS - 19-20 N2 - Gastrinoma is the most frequent functional pancreaticoduodenal endocrine tumor in patients with multiple endocrine neoplasia type 1 (MEN1) and one major determinant of mortality in this syndrome. Whether routine surgical exploration should be performed in a patient with MEN1 associated Zollinger-Ellison syndrome (ZES) to possibly reduce the malignant spread and eventually increase survival still remains controversial. There is not only disagreement about the indication for surgical exploration, but also what type of procedure should be performed, since sufficient evidence-based data are not available. The article discusses the available data on treatment strategies of MEN1 associated ZES. SN - 0043-5325 UR - https://www.unboundmedicine.com/medline/citation/17985096/Surgical_aspects_of_gastrinoma_in_multiple_endocrine_neoplasia_type_1_ L2 - https://dx.doi.org/10.1007/s00508-007-0883-3 DB - PRIME DP - Unbound Medicine ER -