Tags

Type your tag names separated by a space and hit enter

Isolation of Crithmum maritimum L. volatile oil by supercritical carbon dioxide extraction and biological assays.
Nat Prod Res. 2007 Nov; 21(13):1145-50.NP

Abstract

The chemical composition of the volatile concentrate obtained by supercritical CO2 extraction of aerial parts of Crithmum maritimum L. growing spontaneously in one area of Mediterranean coast (Buggerru, Sardinia Island, Italy) and in two areas of the Atlantic coast (Figueira da Foz and S. Pedro de Moel, Portugal) was investigated by GC and GC-MS. The major oil components identified were p-cymene, beta-phellandrene, gamma-terpinene, thymol methyl ether and dillapiole. The results showed the presence of two chemotypes of C. maritimum with different dillapiole contents, ranging from 0.2 to 64.2% in Portuguese and Italian plants, respectively. The minimal inhibitory concentration (MIC) and the minimal lethal concentration (MLC) were used to evaluate the antifungal activity of the oils against yeasts and dermatophyte strains. All the oils exhibited significant antifungal activity against dermatophyte strains. The oil with the higher amount of dillapiole (64.2%) was the most active with MIC values ranging from 0.08-0.32 microL mL(-1).

Authors+Show Affiliations

Marongiu B
Dipartimento di Scienze Chimiche, Università degli Studi di Cagliari, Cittadella Universitaria di Monserrato, 09042 Cagliari, Italy. maronb@unica.it
Maxia A
No affiliation info available
Piras A
No affiliation info available
Porcedda S
No affiliation info available
Tuveri E
No affiliation info available
Gonçalves MJ
No affiliation info available
Cavaleiro C
No affiliation info available
Salgueiro L
No affiliation info available

MeSH

Allyl CompoundsAntifungal AgentsApiaceaeCarbon DioxideChromatography, Supercritical FluidDioxolesMicrobial Sensitivity TestsMitosporic FungiOils, VolatilePlant Leaves

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17987493

Citation

Marongiu, B, et al. "Isolation of Crithmum Maritimum L. Volatile Oil By Supercritical Carbon Dioxide Extraction and Biological Assays." Natural Product Research, vol. 21, no. 13, 2007, pp. 1145-50.
Marongiu B, Maxia A, Piras A, et al. Isolation of Crithmum maritimum L. volatile oil by supercritical carbon dioxide extraction and biological assays. Nat Prod Res. 2007;21(13):1145-50.
Marongiu, B., Maxia, A., Piras, A., Porcedda, S., Tuveri, E., Gonçalves, M. J., Cavaleiro, C., & Salgueiro, L. (2007). Isolation of Crithmum maritimum L. volatile oil by supercritical carbon dioxide extraction and biological assays. Natural Product Research, 21(13), 1145-50.
Marongiu B, et al. Isolation of Crithmum Maritimum L. Volatile Oil By Supercritical Carbon Dioxide Extraction and Biological Assays. Nat Prod Res. 2007;21(13):1145-50. PubMed PMID: 17987493.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Isolation of Crithmum maritimum L. volatile oil by supercritical carbon dioxide extraction and biological assays. AU - Marongiu,B, AU - Maxia,A, AU - Piras,A, AU - Porcedda,S, AU - Tuveri,E, AU - Gonçalves,M J, AU - Cavaleiro,C, AU - Salgueiro,L, PY - 2007/11/8/pubmed PY - 2008/1/23/medline PY - 2007/11/8/entrez SP - 1145 EP - 50 JF - Natural product research JO - Nat Prod Res VL - 21 IS - 13 N2 - The chemical composition of the volatile concentrate obtained by supercritical CO2 extraction of aerial parts of Crithmum maritimum L. growing spontaneously in one area of Mediterranean coast (Buggerru, Sardinia Island, Italy) and in two areas of the Atlantic coast (Figueira da Foz and S. Pedro de Moel, Portugal) was investigated by GC and GC-MS. The major oil components identified were p-cymene, beta-phellandrene, gamma-terpinene, thymol methyl ether and dillapiole. The results showed the presence of two chemotypes of C. maritimum with different dillapiole contents, ranging from 0.2 to 64.2% in Portuguese and Italian plants, respectively. The minimal inhibitory concentration (MIC) and the minimal lethal concentration (MLC) were used to evaluate the antifungal activity of the oils against yeasts and dermatophyte strains. All the oils exhibited significant antifungal activity against dermatophyte strains. The oil with the higher amount of dillapiole (64.2%) was the most active with MIC values ranging from 0.08-0.32 microL mL(-1). SN - 1478-6419 UR - https://www.unboundmedicine.com/medline/citation/17987493/Isolation_of_Crithmum_maritimum_L__volatile_oil_by_supercritical_carbon_dioxide_extraction_and_biological_assays_ DB - PRIME DP - Unbound Medicine ER -