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Application of matrix solid-phase dispersion in the determination of acrylamide in potato chips.
J Chromatogr A. 2007 Dec 14; 1175(1):1-6.JC

Abstract

A sample preparation technique based on matrix solid-phase dispersion (MSPD) was applied to the determination of acrylamide in potato chips. Samples (0.5 g) were ground and dispersed in C18 (2g), transferred to an empty column, and after a previous clean-up with n-hexane to eliminate fat, acrylamide was eluted with water (4 ml+4 ml). After bromination of the extract the samples were analysed by GC-MS in selected ion monitoring mode. The method presents good recoveries and the limits of detection and of quantification were 12.8 and 38.8 microg kg(-1), respectively. In order to evaluate the performance of the MSPD-GC/MS developed method, 17 potato chips samples were simultaneously analysed by an alternative method based on the extraction of acrylamide with hot water. The results obtained by using both methods were very similar, with a correlation factor (r) of 0.9985. The reported MSPD extraction method revealed to be simpler and faster then previous GC-MS methods used to quantify acrylamide in potato chips.

Authors+Show Affiliations

Fernandes JO
REQUIMTE, Serviço de Bromatologia, Faculdade de Farmácia, Universidade do Porto, Rua Aníbal Cunha, 164, 4099-030 Porto, Portugal. josefer@ff.up.pt
Soares C
No affiliation info available

MeSH

AcrylamideFood AnalysisGas Chromatography-Mass SpectrometrySolanum tuberosumSolid Phase Extraction

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17991477

Citation

Fernandes, José O., and Cristina Soares. "Application of Matrix Solid-phase Dispersion in the Determination of Acrylamide in Potato Chips." Journal of Chromatography. A, vol. 1175, no. 1, 2007, pp. 1-6.
Fernandes JO, Soares C. Application of matrix solid-phase dispersion in the determination of acrylamide in potato chips. J Chromatogr A. 2007;1175(1):1-6.
Fernandes, J. O., & Soares, C. (2007). Application of matrix solid-phase dispersion in the determination of acrylamide in potato chips. Journal of Chromatography. A, 1175(1), 1-6.
Fernandes JO, Soares C. Application of Matrix Solid-phase Dispersion in the Determination of Acrylamide in Potato Chips. J Chromatogr A. 2007 Dec 14;1175(1):1-6. PubMed PMID: 17991477.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Application of matrix solid-phase dispersion in the determination of acrylamide in potato chips. AU - Fernandes,José O, AU - Soares,Cristina, Y1 - 2007/10/18/ PY - 2007/07/24/received PY - 2007/10/02/revised PY - 2007/10/03/accepted PY - 2007/11/10/pubmed PY - 2008/3/7/medline PY - 2007/11/10/entrez SP - 1 EP - 6 JF - Journal of chromatography. A JO - J Chromatogr A VL - 1175 IS - 1 N2 - A sample preparation technique based on matrix solid-phase dispersion (MSPD) was applied to the determination of acrylamide in potato chips. Samples (0.5 g) were ground and dispersed in C18 (2g), transferred to an empty column, and after a previous clean-up with n-hexane to eliminate fat, acrylamide was eluted with water (4 ml+4 ml). After bromination of the extract the samples were analysed by GC-MS in selected ion monitoring mode. The method presents good recoveries and the limits of detection and of quantification were 12.8 and 38.8 microg kg(-1), respectively. In order to evaluate the performance of the MSPD-GC/MS developed method, 17 potato chips samples were simultaneously analysed by an alternative method based on the extraction of acrylamide with hot water. The results obtained by using both methods were very similar, with a correlation factor (r) of 0.9985. The reported MSPD extraction method revealed to be simpler and faster then previous GC-MS methods used to quantify acrylamide in potato chips. SN - 0021-9673 UR - https://www.unboundmedicine.com/medline/citation/17991477/Application_of_matrix_solid_phase_dispersion_in_the_determination_of_acrylamide_in_potato_chips_ DB - PRIME DP - Unbound Medicine ER -