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Molecular epidemiology of rabies virus isolated from different sources during a bat-transmitted human outbreak occurring in Augusto Correa municipality, Brazilian Amazon.
Virology. 2008 Jan 20; 370(2):228-36.V

Abstract

We genetically characterize rabies virus (RABV) strains isolated from human cases, domestic and wild animals during a human outbreak of bat-transmitted rabies in Augusto Correa municipality, Pará state, Brazilian Amazon in 2005. Partial nucleotide sequences of the N gene (491 bp) were obtained for all strains, and phylogenetic analysis grouped these into two major clades (Pará and Central-Southeast) and identified them as bat-related viruses genotype I, Desmodus rotundus antigenic variant 3 (AgV3). A molecular clock was used to estimate the time of emergence for each RABV isolate. The molecular data from this study suggest the association of vampire bats with human and domestic animal cases reported in the outbreak, the circulation of at least two predominant lineages in the Pará state, and also a geographic association to lineages dispersion.

Authors+Show Affiliations

Departamento de Arbovirologia e Febres Hemorrágicas, Instituto Evandro Chagas, Belém, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17996263

Citation

Barbosa, Taciana Fernandes Souza, et al. "Molecular Epidemiology of Rabies Virus Isolated From Different Sources During a Bat-transmitted Human Outbreak Occurring in Augusto Correa Municipality, Brazilian Amazon." Virology, vol. 370, no. 2, 2008, pp. 228-36.
Barbosa TF, Medeiros DB, Travassos da Rosa ES, et al. Molecular epidemiology of rabies virus isolated from different sources during a bat-transmitted human outbreak occurring in Augusto Correa municipality, Brazilian Amazon. Virology. 2008;370(2):228-36.
Barbosa, T. F., Medeiros, D. B., Travassos da Rosa, E. S., Casseb, L. M., Medeiros, R., Pereira, A. d. e. . S., Vallinoto, A. C., Vallinoto, M., Begot, A. L., Lima, R. J., Vasconcelos, P. F., & Nunes, M. R. (2008). Molecular epidemiology of rabies virus isolated from different sources during a bat-transmitted human outbreak occurring in Augusto Correa municipality, Brazilian Amazon. Virology, 370(2), 228-36.
Barbosa TF, et al. Molecular Epidemiology of Rabies Virus Isolated From Different Sources During a Bat-transmitted Human Outbreak Occurring in Augusto Correa Municipality, Brazilian Amazon. Virology. 2008 Jan 20;370(2):228-36. PubMed PMID: 17996263.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Molecular epidemiology of rabies virus isolated from different sources during a bat-transmitted human outbreak occurring in Augusto Correa municipality, Brazilian Amazon. AU - Barbosa,Taciana Fernandes Souza, AU - Medeiros,Daniele Barbosa de Almeida, AU - Travassos da Rosa,Elizabeth Salbe, AU - Casseb,Lívia Medeiros Neves, AU - Medeiros,Rita, AU - Pereira,Armando de Souza, AU - Vallinoto,Antonio Carlos Rosário, AU - Vallinoto,Marcelo, AU - Begot,Alberto Lopes, AU - Lima,Reynaldo José da Silva, AU - Vasconcelos,Pedro Fernando da Costa, AU - Nunes,Márcio RobertoTeixeira, Y1 - 2007/11/08/ PY - 2007/06/18/received PY - 2007/08/14/revised PY - 2007/10/05/accepted PY - 2007/11/13/pubmed PY - 2008/2/21/medline PY - 2007/11/13/entrez SP - 228 EP - 36 JF - Virology JO - Virology VL - 370 IS - 2 N2 - We genetically characterize rabies virus (RABV) strains isolated from human cases, domestic and wild animals during a human outbreak of bat-transmitted rabies in Augusto Correa municipality, Pará state, Brazilian Amazon in 2005. Partial nucleotide sequences of the N gene (491 bp) were obtained for all strains, and phylogenetic analysis grouped these into two major clades (Pará and Central-Southeast) and identified them as bat-related viruses genotype I, Desmodus rotundus antigenic variant 3 (AgV3). A molecular clock was used to estimate the time of emergence for each RABV isolate. The molecular data from this study suggest the association of vampire bats with human and domestic animal cases reported in the outbreak, the circulation of at least two predominant lineages in the Pará state, and also a geographic association to lineages dispersion. SN - 0042-6822 UR - https://www.unboundmedicine.com/medline/citation/17996263/Molecular_epidemiology_of_rabies_virus_isolated_from_different_sources_during_a_bat_transmitted_human_outbreak_occurring_in_Augusto_Correa_municipality_Brazilian_Amazon_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0042-6822(07)00661-7 DB - PRIME DP - Unbound Medicine ER -