Tags

Type your tag names separated by a space and hit enter

Long-term trends of angiotensin-converting enzyme inhibitor and angiotensin-receptor blocker use after heart failure hospitalization in community-dwelling seniors.
Int J Cardiol. 2008 Apr 10; 125(2):172-7.IJ

Abstract

BACKGROUND

Despite multiple trials demonstrating the benefit of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin-receptor blockers (ARBs) for heart failure (HF) patients with systolic dysfunction, studies have reported underuse of these drugs. Little is known about recent trends in the use of ACEI/ARB in community-dwelling seniors.

METHODS

Using administrative data from pharmacy assistance programs and Medicare in two states, we identified all patients hospitalized for HF between 1995 and 2004 who survived >or=90 days after discharge. The study outcomes were filled prescriptions for an ACEI or ARB within 90 days after discharge. We assessed age, gender, race, and comorbidities. Multivariate modified Poisson regression was used to analyze temporal trends.

RESULTS

Of 54,453 patients identified, 26,166 (48%) filled prescriptions for ACEIs/ARBs within 90 days after discharge from HF, but utilization of these drugs did not increase during the decade studied. Among those who were on ACEI/ARB before the index hospitalization, 74% filled at least one ACEI/ARB prescription within 90 days after the hospitalization. These results were similar among the subgroup of HF patients with prior MI.

CONCLUSIONS

Use of ACEI/ARB after discharge from HF hospitalization in seniors did not increase over the decade of observation and may still be inadequate.

Authors+Show Affiliations

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02120, United States. ssetoguchi@partners.orgNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

17997175

Citation

Setoguchi, Soko, et al. "Long-term Trends of Angiotensin-converting Enzyme Inhibitor and Angiotensin-receptor Blocker Use After Heart Failure Hospitalization in Community-dwelling Seniors." International Journal of Cardiology, vol. 125, no. 2, 2008, pp. 172-7.
Setoguchi S, Levin R, Winkelmayer WC. Long-term trends of angiotensin-converting enzyme inhibitor and angiotensin-receptor blocker use after heart failure hospitalization in community-dwelling seniors. Int J Cardiol. 2008;125(2):172-7.
Setoguchi, S., Levin, R., & Winkelmayer, W. C. (2008). Long-term trends of angiotensin-converting enzyme inhibitor and angiotensin-receptor blocker use after heart failure hospitalization in community-dwelling seniors. International Journal of Cardiology, 125(2), 172-7.
Setoguchi S, Levin R, Winkelmayer WC. Long-term Trends of Angiotensin-converting Enzyme Inhibitor and Angiotensin-receptor Blocker Use After Heart Failure Hospitalization in Community-dwelling Seniors. Int J Cardiol. 2008 Apr 10;125(2):172-7. PubMed PMID: 17997175.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term trends of angiotensin-converting enzyme inhibitor and angiotensin-receptor blocker use after heart failure hospitalization in community-dwelling seniors. AU - Setoguchi,Soko, AU - Levin,Raisa, AU - Winkelmayer,Wolfgang C, Y1 - 2007/11/07/ PY - 2007/11/13/pubmed PY - 2008/6/11/medline PY - 2007/11/13/entrez SP - 172 EP - 7 JF - International journal of cardiology JO - Int J Cardiol VL - 125 IS - 2 N2 - BACKGROUND: Despite multiple trials demonstrating the benefit of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin-receptor blockers (ARBs) for heart failure (HF) patients with systolic dysfunction, studies have reported underuse of these drugs. Little is known about recent trends in the use of ACEI/ARB in community-dwelling seniors. METHODS: Using administrative data from pharmacy assistance programs and Medicare in two states, we identified all patients hospitalized for HF between 1995 and 2004 who survived >or=90 days after discharge. The study outcomes were filled prescriptions for an ACEI or ARB within 90 days after discharge. We assessed age, gender, race, and comorbidities. Multivariate modified Poisson regression was used to analyze temporal trends. RESULTS: Of 54,453 patients identified, 26,166 (48%) filled prescriptions for ACEIs/ARBs within 90 days after discharge from HF, but utilization of these drugs did not increase during the decade studied. Among those who were on ACEI/ARB before the index hospitalization, 74% filled at least one ACEI/ARB prescription within 90 days after the hospitalization. These results were similar among the subgroup of HF patients with prior MI. CONCLUSIONS: Use of ACEI/ARB after discharge from HF hospitalization in seniors did not increase over the decade of observation and may still be inadequate. SN - 1874-1754 UR - https://www.unboundmedicine.com/medline/citation/17997175/Long_term_trends_of_angiotensin_converting_enzyme_inhibitor_and_angiotensin_receptor_blocker_use_after_heart_failure_hospitalization_in_community_dwelling_seniors_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0167-5273(07)01624-5 DB - PRIME DP - Unbound Medicine ER -