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Health-related quality of life in methylphenidate-treated children with attention-deficit-hyperactivity disorder: results from a Taiwanese sample.
Aust N Z J Psychiatry. 2007 Dec; 41(12):998-1004.AN

Abstract

OBJECTIVE

Attention-deficit-hyperactivity disorder (ADHD) is the most common neuropsychiatric disorder of childhood. The purpose of the present study was to assess the health-related quality of life (HRQL) in methylphenidate-treated school-age children with ADHD as compared with healthy children in a Taiwanese population.

METHODS

Subjects were 6-15 years of age with ADHD who were currently receiving methylphenidate treatment (total n=119). Subjects were compared to 129 healthy children recruited from the community. Child Health Questionnaire Parent Form-50 (CHQ-PF-50), a functional health status measure of HRQL was arranged for parents to complete. Disease-related variables were analysed to determine their relationship and predictive power with HRQL of children.

RESULTS

The HRQL of methylphenidate-treated children with ADHD was rated worse than that of community children in all the psychosocial subscales and the Psychosocial Summary Score of CHQ-PF-50. In addition, the problems of ADHD children interfered with family activities and family cohesion significantly. Moreover, improvement of ADHD core symptoms after medication treatment predicted higher psychosocial functioning. This effect was independent of children's current age, age receiving diagnosis, age starting and duration of medication treatment but was not independent of ADHD comorbidity.

CONCLUSION

This study may serve as one of the cross-cultural validations of ADHD as a common concern for children and families worldwide. After methylphenidate treatment, parents of Taiwanese children with ADHD still reported them to have poorer health outcomes than control children across almost all domains of HRQL. Improvement of HRQL should be integrated in the overall treatment plan for children with ADHD.

Authors+Show Affiliations

Department of Psychiatry, Kaohsiung Medical University and Chung-Ho Memorial Hospital, Taiwan. pichya@kmu.edu.twNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17999272

Citation

Yang, Pinchen, et al. "Health-related Quality of Life in Methylphenidate-treated Children With Attention-deficit-hyperactivity Disorder: Results From a Taiwanese Sample." The Australian and New Zealand Journal of Psychiatry, vol. 41, no. 12, 2007, pp. 998-1004.
Yang P, Hsu HY, Chiou SS, et al. Health-related quality of life in methylphenidate-treated children with attention-deficit-hyperactivity disorder: results from a Taiwanese sample. Aust N Z J Psychiatry. 2007;41(12):998-1004.
Yang, P., Hsu, H. Y., Chiou, S. S., & Chao, M. C. (2007). Health-related quality of life in methylphenidate-treated children with attention-deficit-hyperactivity disorder: results from a Taiwanese sample. The Australian and New Zealand Journal of Psychiatry, 41(12), 998-1004.
Yang P, et al. Health-related Quality of Life in Methylphenidate-treated Children With Attention-deficit-hyperactivity Disorder: Results From a Taiwanese Sample. Aust N Z J Psychiatry. 2007;41(12):998-1004. PubMed PMID: 17999272.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Health-related quality of life in methylphenidate-treated children with attention-deficit-hyperactivity disorder: results from a Taiwanese sample. AU - Yang,Pinchen, AU - Hsu,Hsiu-Yi, AU - Chiou,Shyh-Shin, AU - Chao,Mei-Chyn, PY - 2007/11/14/pubmed PY - 2008/3/1/medline PY - 2007/11/14/entrez SP - 998 EP - 1004 JF - The Australian and New Zealand journal of psychiatry JO - Aust N Z J Psychiatry VL - 41 IS - 12 N2 - OBJECTIVE: Attention-deficit-hyperactivity disorder (ADHD) is the most common neuropsychiatric disorder of childhood. The purpose of the present study was to assess the health-related quality of life (HRQL) in methylphenidate-treated school-age children with ADHD as compared with healthy children in a Taiwanese population. METHODS: Subjects were 6-15 years of age with ADHD who were currently receiving methylphenidate treatment (total n=119). Subjects were compared to 129 healthy children recruited from the community. Child Health Questionnaire Parent Form-50 (CHQ-PF-50), a functional health status measure of HRQL was arranged for parents to complete. Disease-related variables were analysed to determine their relationship and predictive power with HRQL of children. RESULTS: The HRQL of methylphenidate-treated children with ADHD was rated worse than that of community children in all the psychosocial subscales and the Psychosocial Summary Score of CHQ-PF-50. In addition, the problems of ADHD children interfered with family activities and family cohesion significantly. Moreover, improvement of ADHD core symptoms after medication treatment predicted higher psychosocial functioning. This effect was independent of children's current age, age receiving diagnosis, age starting and duration of medication treatment but was not independent of ADHD comorbidity. CONCLUSION: This study may serve as one of the cross-cultural validations of ADHD as a common concern for children and families worldwide. After methylphenidate treatment, parents of Taiwanese children with ADHD still reported them to have poorer health outcomes than control children across almost all domains of HRQL. Improvement of HRQL should be integrated in the overall treatment plan for children with ADHD. SN - 0004-8674 UR - https://www.unboundmedicine.com/medline/citation/17999272/Health_related_quality_of_life_in_methylphenidate_treated_children_with_attention_deficit_hyperactivity_disorder:_results_from_a_Taiwanese_sample_ L2 - https://journals.sagepub.com/doi/10.1080/00048670701689451?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -