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Treatment of heart failure with normal left ventricular ejection fraction.
Compr Ther 2007; 33(4):223-30CT

Abstract

Underlying causes and precipitating causes of heart failure (HF) should be treated when possible. Persons with HF and normal left ventricular ejection fraction (LVEF) should have maintenance of sinus rhythm, treatment of hypertension, myocardial ischemia, dyslipidemia, and anemia, slowing of the ventricular rate below 90 bpm, and reduction of salt overload. First-line drug treatment in the management of these persons is the use of loop diuretics combined with beta blockers and angiotensin-converting enzyme (ACE) inhibitors. If persons are unable to tolerate ACE inhibitors because of cough, angioneurotic edema, rash, or altered taste sensation, angiotensin II type I receptor antagonists (ARBs) should be given. If HF persists despite diuretics, beta blockers, and ACE inhibitors or ARBs, isosorbide dinitrate plus hydralazine should be administered. Beta blockers, verapamil, diltiazem, and digoxin may be used to slow a rapid ventricular rate in persons with supraventricular tachyarrhythmias. Digoxin should not be used in persons with HF in sinus rhythm with normal LVEF. Exercise training should be encouraged in persons with mild to moderate HF to improve functional status and to decrease symptoms.

Authors+Show Affiliations

Department of Medicine, Division of Cardiology, Westchester Medical Center/New York Medical College, Macy Pavillion, Room 138, Valhalla, NY 10595, USA. WSAronow@aol.com

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

18025614

Citation

Aronow, Wilbert S.. "Treatment of Heart Failure With Normal Left Ventricular Ejection Fraction." Comprehensive Therapy, vol. 33, no. 4, 2007, pp. 223-30.
Aronow WS. Treatment of heart failure with normal left ventricular ejection fraction. Compr Ther. 2007;33(4):223-30.
Aronow, W. S. (2007). Treatment of heart failure with normal left ventricular ejection fraction. Comprehensive Therapy, 33(4), pp. 223-30.
Aronow WS. Treatment of Heart Failure With Normal Left Ventricular Ejection Fraction. Compr Ther. 2007;33(4):223-30. PubMed PMID: 18025614.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment of heart failure with normal left ventricular ejection fraction. A1 - Aronow,Wilbert S, PY - 2007/07/19/received PY - 1999/11/30/revised PY - 2007/07/24/accepted PY - 2007/11/21/pubmed PY - 2008/3/6/medline PY - 2007/11/21/entrez SP - 223 EP - 30 JF - Comprehensive therapy JO - Compr Ther VL - 33 IS - 4 N2 - Underlying causes and precipitating causes of heart failure (HF) should be treated when possible. Persons with HF and normal left ventricular ejection fraction (LVEF) should have maintenance of sinus rhythm, treatment of hypertension, myocardial ischemia, dyslipidemia, and anemia, slowing of the ventricular rate below 90 bpm, and reduction of salt overload. First-line drug treatment in the management of these persons is the use of loop diuretics combined with beta blockers and angiotensin-converting enzyme (ACE) inhibitors. If persons are unable to tolerate ACE inhibitors because of cough, angioneurotic edema, rash, or altered taste sensation, angiotensin II type I receptor antagonists (ARBs) should be given. If HF persists despite diuretics, beta blockers, and ACE inhibitors or ARBs, isosorbide dinitrate plus hydralazine should be administered. Beta blockers, verapamil, diltiazem, and digoxin may be used to slow a rapid ventricular rate in persons with supraventricular tachyarrhythmias. Digoxin should not be used in persons with HF in sinus rhythm with normal LVEF. Exercise training should be encouraged in persons with mild to moderate HF to improve functional status and to decrease symptoms. SN - 0098-8243 UR - https://www.unboundmedicine.com/medline/citation/18025614/Treatment_of_heart_failure_with_normal_left_ventricular_ejection_fraction_ L2 - https://medlineplus.gov/heartfailure.html DB - PRIME DP - Unbound Medicine ER -