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Diffusion-weighted imaging of the appendicular skeleton with a non-Carr-Purcell-Meiboom-Gill single-shot fast spin-echo sequence.
AJR Am J Roentgenol. 2007 Dec; 189(6):1494-501.AA

Abstract

OBJECTIVE

The objective of our study was to prospectively evaluate the signal-to-noise ratio (SNR) improvement in diffusion-weighted imaging (DWI) of the appendicular skeleton with the use of a newly developed non-Carr-Purcell-Meiboom-Gill (non-CPMG) single-shot fast spin-echo (SSFSE) sequence and to evaluate its effect on apparent diffusion coefficient (ADC) measurements.

SUBJECTS AND METHODS

DWI of the bone was performed in 32 patients with an echo-planar imaging (EPI)-based sequence followed by a non-CPMG SSFSE technique. SNR and ADC values were measured over a lesion-free right femoral head. A score was assigned for each set of images to assess image quality. When a bone lesion was present, contrast-to-noise ratio (CNR) and ADC were also measured. Paired Student's t tests were used for statistical analysis.

RESULTS

The mean (+/- SD) SNR values were 9.89 +/- 2.20 and 81.68 +/- 4.87 for EPI and non-CPMG SSFSE DWI, respectively. SNR values associated with the non-CPMG SSFSE technique were found to be significantly higher than those measured with the EPI-based DWI technique (p < 0.01). Mean ADCs of the bone were 0.57 +/- 0.20 and 0.29 +/- 0.15 x 10(-3) mm2/s, respectively, for EPI and non-CPMG SSFSE DWI. Image quality scores were higher for the non-CPMG SSFSE DWI technique (p < 0.05) than for the EPI-based DWI technique. Overall lesion CNR was found to be higher in DWI performed with the non-CPMG SSFSE technique.

CONCLUSION

The non-CPMG SSFSE technique provides a significant improvement over the currently used EPI-based DWI technique and has the potential to be a powerful tool in imaging the appendicular skeleton.

Authors+Show Affiliations

Department of Radiology, Gazi University School of Medicine, Besevler, Ankara 06510, Turkey. yusuf@tr.netNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18029891

Citation

Oner, Ali Yusuf, et al. "Diffusion-weighted Imaging of the Appendicular Skeleton With a non-Carr-Purcell-Meiboom-Gill Single-shot Fast Spin-echo Sequence." AJR. American Journal of Roentgenology, vol. 189, no. 6, 2007, pp. 1494-501.
Oner AY, Aggunlu L, Akpek S, et al. Diffusion-weighted imaging of the appendicular skeleton with a non-Carr-Purcell-Meiboom-Gill single-shot fast spin-echo sequence. AJR Am J Roentgenol. 2007;189(6):1494-501.
Oner, A. Y., Aggunlu, L., Akpek, S., Tali, T., & Celik, A. (2007). Diffusion-weighted imaging of the appendicular skeleton with a non-Carr-Purcell-Meiboom-Gill single-shot fast spin-echo sequence. AJR. American Journal of Roentgenology, 189(6), 1494-501.
Oner AY, et al. Diffusion-weighted Imaging of the Appendicular Skeleton With a non-Carr-Purcell-Meiboom-Gill Single-shot Fast Spin-echo Sequence. AJR Am J Roentgenol. 2007;189(6):1494-501. PubMed PMID: 18029891.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diffusion-weighted imaging of the appendicular skeleton with a non-Carr-Purcell-Meiboom-Gill single-shot fast spin-echo sequence. AU - Oner,Ali Yusuf, AU - Aggunlu,Levent, AU - Akpek,Sergin, AU - Tali,Turgut, AU - Celik,Azim, PY - 2007/11/22/pubmed PY - 2007/12/18/medline PY - 2007/11/22/entrez SP - 1494 EP - 501 JF - AJR. American journal of roentgenology JO - AJR Am J Roentgenol VL - 189 IS - 6 N2 - OBJECTIVE: The objective of our study was to prospectively evaluate the signal-to-noise ratio (SNR) improvement in diffusion-weighted imaging (DWI) of the appendicular skeleton with the use of a newly developed non-Carr-Purcell-Meiboom-Gill (non-CPMG) single-shot fast spin-echo (SSFSE) sequence and to evaluate its effect on apparent diffusion coefficient (ADC) measurements. SUBJECTS AND METHODS: DWI of the bone was performed in 32 patients with an echo-planar imaging (EPI)-based sequence followed by a non-CPMG SSFSE technique. SNR and ADC values were measured over a lesion-free right femoral head. A score was assigned for each set of images to assess image quality. When a bone lesion was present, contrast-to-noise ratio (CNR) and ADC were also measured. Paired Student's t tests were used for statistical analysis. RESULTS: The mean (+/- SD) SNR values were 9.89 +/- 2.20 and 81.68 +/- 4.87 for EPI and non-CPMG SSFSE DWI, respectively. SNR values associated with the non-CPMG SSFSE technique were found to be significantly higher than those measured with the EPI-based DWI technique (p < 0.01). Mean ADCs of the bone were 0.57 +/- 0.20 and 0.29 +/- 0.15 x 10(-3) mm2/s, respectively, for EPI and non-CPMG SSFSE DWI. Image quality scores were higher for the non-CPMG SSFSE DWI technique (p < 0.05) than for the EPI-based DWI technique. Overall lesion CNR was found to be higher in DWI performed with the non-CPMG SSFSE technique. CONCLUSION: The non-CPMG SSFSE technique provides a significant improvement over the currently used EPI-based DWI technique and has the potential to be a powerful tool in imaging the appendicular skeleton. SN - 1546-3141 UR - https://www.unboundmedicine.com/medline/citation/18029891/Diffusion_weighted_imaging_of_the_appendicular_skeleton_with_a_non_Carr_Purcell_Meiboom_Gill_single_shot_fast_spin_echo_sequence_ L2 - https://www.ajronline.org/doi/10.2214/AJR.07.2512 DB - PRIME DP - Unbound Medicine ER -