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Experimental validation of a time-domain-based wave propagation model of blood flow in viscoelastic vessels.
J Biomech 2008; 41(2):284-91JB

Abstract

Time-domain-based one-dimensional wave propagation models of the arterial system are preferable over one-dimensional wave propagation models in the frequency domain since the latter neglect the non-linear convection forces present in the physiological situation, especially when the vessel is tapered. Moreover, one-dimensional wave propagation models of the arterial system can be used to provide boundary conditions for fully three-dimensional fluid-structure interaction computations that are usually defined in the time domain. In this study, a time-domain-based one-dimensional wave propagation model in a cross-sectional area, flow and pressure (A,q,p)-formulation is developed. Using this formulation, a constitutive law that includes viscoelasticity based on the mechanical behaviour of a Kelvin body, is introduced. The resulting pressure and flow waves travelling through a straight and tapered vessel are compared to experimental data obtained from measurements in an in vitro setup. The model presented shows to be well suited to predict wave propagation through these straight and tapered vessels with viscoelastic wall properties and hereto can serve as a time-domain-based method to model wave propagation in the human arterial system.

Authors+Show Affiliations

Department of Biomedical Engineering, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Studies
Journal Article
Research Support, Non-U.S. Gov't
Validation Studies

Language

eng

PubMed ID

18031750

Citation

Bessems, David, et al. "Experimental Validation of a Time-domain-based Wave Propagation Model of Blood Flow in Viscoelastic Vessels." Journal of Biomechanics, vol. 41, no. 2, 2008, pp. 284-91.
Bessems D, Giannopapa CG, Rutten MC, et al. Experimental validation of a time-domain-based wave propagation model of blood flow in viscoelastic vessels. J Biomech. 2008;41(2):284-91.
Bessems, D., Giannopapa, C. G., Rutten, M. C., & van de Vosse, F. N. (2008). Experimental validation of a time-domain-based wave propagation model of blood flow in viscoelastic vessels. Journal of Biomechanics, 41(2), pp. 284-91.
Bessems D, et al. Experimental Validation of a Time-domain-based Wave Propagation Model of Blood Flow in Viscoelastic Vessels. J Biomech. 2008;41(2):284-91. PubMed PMID: 18031750.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Experimental validation of a time-domain-based wave propagation model of blood flow in viscoelastic vessels. AU - Bessems,David, AU - Giannopapa,Christina G, AU - Rutten,Marcel C M, AU - van de Vosse,Frans N, Y1 - 2007/11/26/ PY - 2007/04/17/received PY - 2007/09/17/revised PY - 2007/09/18/accepted PY - 2007/11/23/pubmed PY - 2008/5/1/medline PY - 2007/11/23/entrez SP - 284 EP - 91 JF - Journal of biomechanics JO - J Biomech VL - 41 IS - 2 N2 - Time-domain-based one-dimensional wave propagation models of the arterial system are preferable over one-dimensional wave propagation models in the frequency domain since the latter neglect the non-linear convection forces present in the physiological situation, especially when the vessel is tapered. Moreover, one-dimensional wave propagation models of the arterial system can be used to provide boundary conditions for fully three-dimensional fluid-structure interaction computations that are usually defined in the time domain. In this study, a time-domain-based one-dimensional wave propagation model in a cross-sectional area, flow and pressure (A,q,p)-formulation is developed. Using this formulation, a constitutive law that includes viscoelasticity based on the mechanical behaviour of a Kelvin body, is introduced. The resulting pressure and flow waves travelling through a straight and tapered vessel are compared to experimental data obtained from measurements in an in vitro setup. The model presented shows to be well suited to predict wave propagation through these straight and tapered vessels with viscoelastic wall properties and hereto can serve as a time-domain-based method to model wave propagation in the human arterial system. SN - 0021-9290 UR - https://www.unboundmedicine.com/medline/citation/18031750/Experimental_validation_of_a_time_domain_based_wave_propagation_model_of_blood_flow_in_viscoelastic_vessels_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0021-9290(07)00392-2 DB - PRIME DP - Unbound Medicine ER -