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An intrasellar rhabdomyosarcoma misdiagnosed as pituitary adenoma.
Surg Neurol. 2007; 68 Suppl 2:S29-33; discussion S33.SN

Abstract

BACKGROUND

Rhabdomyosarcoma is a malignant tumor of the skeletal muscle cells. Those tumors mainly affect children and arise in primitive fetal mesenchyme even at sites that do not contain skeletal muscle. However, very few intracranial rhabdomyosarcomas have been reported. No previous case of primary intrasellar rhabdomyosarcoma except for 1 case has been reported in the literature.

CASE DESCRIPTION

A 44-year-old woman presented with fatigue and diplopia associated with amenorrhea and galactorrhea. Visual field evaluation revealed a superior temporal deficit in both eyes. A right afferent pupillary defect was present. Magnetic resonance imaging revealed an intrasellar tumor with suprasellar extension. The tumor involved the sella turcica and right cavernous sinus. The patient was preoperatively diagnosed as pituitary adenoma, which was confirmed pathologically as rhabdomyosarcoma after the operation.

CONCLUSIONS

Our findings suggest that rhabdomyosarcoma should be considered in the differential diagnosis of a primary intrasellar neoplasm.

Authors+Show Affiliations

Department of Neurosurgery, XinHua Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200092, People's Republic of China. zhongmdphd@126.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

18037040

Citation

Zhong, Jun, et al. "An Intrasellar Rhabdomyosarcoma Misdiagnosed as Pituitary Adenoma." Surgical Neurology, vol. 68 Suppl 2, 2007, pp. S29-33; discussion S33.
Zhong J, Li ST, Yao XH, et al. An intrasellar rhabdomyosarcoma misdiagnosed as pituitary adenoma. Surg Neurol. 2007;68 Suppl 2:S29-33; discussion S33.
Zhong, J., Li, S. T., Yao, X. H., Jin, B., & Wan, L. (2007). An intrasellar rhabdomyosarcoma misdiagnosed as pituitary adenoma. Surgical Neurology, 68 Suppl 2, S29-33; discussion S33.
Zhong J, et al. An Intrasellar Rhabdomyosarcoma Misdiagnosed as Pituitary Adenoma. Surg Neurol. 2007;68 Suppl 2:S29-33; discussion S33. PubMed PMID: 18037040.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An intrasellar rhabdomyosarcoma misdiagnosed as pituitary adenoma. AU - Zhong,Jun, AU - Li,Shi-Ting, AU - Yao,Xiao-Hong, AU - Jin,Biao, AU - Wan,Liang, PY - 2006/06/22/received PY - 2007/01/30/accepted PY - 2007/12/6/pubmed PY - 2008/2/6/medline PY - 2007/12/6/entrez SP - S29-33; discussion S33 JF - Surgical neurology JO - Surg Neurol VL - 68 Suppl 2 N2 - BACKGROUND: Rhabdomyosarcoma is a malignant tumor of the skeletal muscle cells. Those tumors mainly affect children and arise in primitive fetal mesenchyme even at sites that do not contain skeletal muscle. However, very few intracranial rhabdomyosarcomas have been reported. No previous case of primary intrasellar rhabdomyosarcoma except for 1 case has been reported in the literature. CASE DESCRIPTION: A 44-year-old woman presented with fatigue and diplopia associated with amenorrhea and galactorrhea. Visual field evaluation revealed a superior temporal deficit in both eyes. A right afferent pupillary defect was present. Magnetic resonance imaging revealed an intrasellar tumor with suprasellar extension. The tumor involved the sella turcica and right cavernous sinus. The patient was preoperatively diagnosed as pituitary adenoma, which was confirmed pathologically as rhabdomyosarcoma after the operation. CONCLUSIONS: Our findings suggest that rhabdomyosarcoma should be considered in the differential diagnosis of a primary intrasellar neoplasm. SN - 0090-3019 UR - https://www.unboundmedicine.com/medline/citation/18037040/An_intrasellar_rhabdomyosarcoma_misdiagnosed_as_pituitary_adenoma_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0090-3019(07)00320-5 DB - PRIME DP - Unbound Medicine ER -