Tags

Type your tag names separated by a space and hit enter

[Relationship between essential tremor, Parkinson's disease and dementia with Lewy bodies].
Rev Neurol. 2007 Dec 1-15; 45(11):689-94.RN

Abstract

INTRODUCTION

Although essential tremor (ET), Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are considered to be distinct illnesses, there is a certain overlap between some of their clinical, pathological and genetic features.

AIM

To conduct a critical examination of the evidence for and against the association between these three pathological conditions.

DEVELOPMENT

The body of evidence supporting the notion of a relation between ET and PD is growing all the time; the same can be said of the fact that a postural tremor may appear years before the onset of other extrapyramidal symptoms, the involvement of common genes in the development of both conditions or the presence of common pathological findings. In addition, it has also been suggested that there are several aspects linking PD and DLB, and it has even been claimed that that they might be part of the clinical spectrum of the same disease. The concept of ET as a benign single-symptom disease has changed in recent years and, since it has been related to cognitive disorders and Lewy bodies in the central nervous system, it is now considered to be a neurodegenerative pathology. CONCLUSIONS. ET, PD and DLB could represent different points on the same clinical spectrum.

Authors+Show Affiliations

Servicio de Neurología, Clinica Nuestra Señora del Rosario. Hospital de la Zarzuela, Madrid, España. pedro_bermejo@hotmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

18050102

Citation

Bermejo, P E., et al. "[Relationship Between Essential Tremor, Parkinson's Disease and Dementia With Lewy Bodies]." Revista De Neurologia, vol. 45, no. 11, 2007, pp. 689-94.
Bermejo PE, Ruiz-Huete C, Terrón C. [Relationship between essential tremor, Parkinson's disease and dementia with Lewy bodies]. Rev Neurol. 2007;45(11):689-94.
Bermejo, P. E., Ruiz-Huete, C., & Terrón, C. (2007). [Relationship between essential tremor, Parkinson's disease and dementia with Lewy bodies]. Revista De Neurologia, 45(11), 689-94.
Bermejo PE, Ruiz-Huete C, Terrón C. [Relationship Between Essential Tremor, Parkinson's Disease and Dementia With Lewy Bodies]. Rev Neurol. 2007 Dec 1-15;45(11):689-94. PubMed PMID: 18050102.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Relationship between essential tremor, Parkinson's disease and dementia with Lewy bodies]. AU - Bermejo,P E, AU - Ruiz-Huete,C, AU - Terrón,C, PY - 2007/12/1/pubmed PY - 2008/2/7/medline PY - 2007/12/1/entrez SP - 689 EP - 94 JF - Revista de neurologia JO - Rev Neurol VL - 45 IS - 11 N2 - INTRODUCTION: Although essential tremor (ET), Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are considered to be distinct illnesses, there is a certain overlap between some of their clinical, pathological and genetic features. AIM: To conduct a critical examination of the evidence for and against the association between these three pathological conditions. DEVELOPMENT: The body of evidence supporting the notion of a relation between ET and PD is growing all the time; the same can be said of the fact that a postural tremor may appear years before the onset of other extrapyramidal symptoms, the involvement of common genes in the development of both conditions or the presence of common pathological findings. In addition, it has also been suggested that there are several aspects linking PD and DLB, and it has even been claimed that that they might be part of the clinical spectrum of the same disease. The concept of ET as a benign single-symptom disease has changed in recent years and, since it has been related to cognitive disorders and Lewy bodies in the central nervous system, it is now considered to be a neurodegenerative pathology. CONCLUSIONS. ET, PD and DLB could represent different points on the same clinical spectrum. SN - 0210-0010 UR - https://www.unboundmedicine.com/medline/citation/18050102/[Relationship_between_essential_tremor_Parkinson's_disease_and_dementia_with_Lewy_bodies]_ L2 - http://www.revneurol.com/LinkOut/formMedLine.asp?Refer=2007460&Revista=RevNeurol DB - PRIME DP - Unbound Medicine ER -