Abstract
OBJECTIVE
To establish chromatographic fingerprint of Sichuan native medicinal plant Alisma plantago-aquatica by RP-HPLC for the quality control.
METHOD
The gradient elution mode was applied in chromatographic separation, and data were analyzed by "Computer Aided Similarity Evaluation" software to compare the quality of A. plantago-aquatica samples from different habitats.
RESULT
The HPLC chromatographic fingerprinting of A. plantago-aquatica with 26 characteristic peaks was established from 17 lots of A. plantago-aquatica samples, peak 16 and 22 were identified as 24-acetyl alisol A and 23-acetyl alisol B, respectively.
CONCLUSION
The chromatographic fingerprinting of A. plantago-aquatica with high specificity can be used to control its quality and assure lot to lot consistency. The RP-HPLC fingerprint method is repeatable, feasible in analysis of A. plantago-aquatica.
TY - JOUR
T1 - [Establishment of chromatographic fingerprint and quality assessment on Sichuan native medicinal plant Alisma plantago-aquatica].
AU - Liu,Hong-Chang,
AU - Yang,Wen-Yu,
AU - Chen,Xing-Fu,
PY - 2007/12/7/pubmed
PY - 2008/11/19/medline
PY - 2007/12/7/entrez
SP - 1844
EP - 7
JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
JO - Zhongguo Zhong Yao Za Zhi
VL - 32
IS - 18
N2 - OBJECTIVE: To establish chromatographic fingerprint of Sichuan native medicinal plant Alisma plantago-aquatica by RP-HPLC for the quality control. METHOD: The gradient elution mode was applied in chromatographic separation, and data were analyzed by "Computer Aided Similarity Evaluation" software to compare the quality of A. plantago-aquatica samples from different habitats. RESULT: The HPLC chromatographic fingerprinting of A. plantago-aquatica with 26 characteristic peaks was established from 17 lots of A. plantago-aquatica samples, peak 16 and 22 were identified as 24-acetyl alisol A and 23-acetyl alisol B, respectively. CONCLUSION: The chromatographic fingerprinting of A. plantago-aquatica with high specificity can be used to control its quality and assure lot to lot consistency. The RP-HPLC fingerprint method is repeatable, feasible in analysis of A. plantago-aquatica.
SN - 1001-5302
UR - https://www.unboundmedicine.com/medline/citation/18051885/[Establishment_of_chromatographic_fingerprint_and_quality_assessment_on_Sichuan_native_medicinal_plant_Alisma_plantago_aquatica]_
DB - PRIME
DP - Unbound Medicine
ER -